Cancer Family
Nervous System Neoplasm
CI-CAN-00000038Explore in graph →
Non-malignant1,523 active trials9 approved drugs210 evidence items
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Cancer Family
CI-CAN-00000038Explore in graph →
Clinical trials
5,871 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02970448 | Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas | completed | Early Phase 1 | 13 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 6, 2026 | clinicaltrials |
| NCT04730869 | Metabolic Therapy Program In Conjunction With Standard Treatment For Glioblastoma | completed | N/A | 18 | Waikato HospitalOTHER | 1 | Aug 6, 2026 | clinicaltrials |
| NCT00911560 |
| Bivalent Vaccine With Escalating Doses of the Immunological Adjuvant OPT-821, in Combination With Oral β-glucan for High-Risk Neuroblastoma |
| completed |
| Phase 1 / Phase 2 |
| 374 |
| Memorial Sloan Kettering Cancer CenterOTHER |
| 1 |
| Aug 5, 2026 |
| clinicaltrials |
| NCT05235074 | OH2 Oncolytic Viral Therapy in Central Nervous System Tumors | completed | Phase 1 / Phase 2 | 40 | Binhui Biopharmaceutical Co., Ltd.INDUSTRY | 1 | Aug 5, 2026 | clinicaltrials |
| NCT02211768 | Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1 | completed | Phase 1 | 10 | National Cancer Institute (NCI)NIH | 1 | Aug 4, 2026 | clinicaltrials |
| NCT06822842 | Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models | completed | — | 1,229 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Aug 4, 2026 | clinicaltrials |
| NCT03900689 | Social Determinants of Health in Glioblastoma Population | completed | — | 100 | Wake Forest University Health SciencesOTHER | 1 | Aug 3, 2026 | clinicaltrials |
| NCT03030066 | Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas | completed | Phase 1 | 47 | Daiichi SankyoINDUSTRY | 1 | Jul 28, 2026 | clinicaltrials |
| NCT01339052 | Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma | completed | Phase 2 | 65 | L. Nicolas Gonzalez Castro, MD, PhDOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT05005715 | Effect of Dexmedetomidine on Quality of Recovery in Non-functioning Pituitary Adenoma Patients Undergoing Endoscopic Transsphenoidal Surgery | completed | Phase 2 | 64 | Seoul National University HospitalOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07716124 | Use of AlignRT System During Stereotactic Radiosurgery | completed | N/A | 20 | Institute of Oncology LjubljanaOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT02902757 | FDG PET/CT in Monitoring Very Early Therapy Response in Patients With Glioblastoma | completed | N/A | 7 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Jul 17, 2026 | clinicaltrials |
| NCT04465643 | Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor | completed | Phase 1 | 13 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jul 10, 2026 | clinicaltrials |
| NCT04743310 | Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System | completed | Phase 2 | 50 | John YuOTHER | 1 | Jul 10, 2026 | clinicaltrials |
| NCT00904241 | Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma | completed | — | 10,000 | Children's Oncology GroupNETWORK | 8 | Jul 9, 2026 | clinicaltrials |
| NCT03477513 | Personalized Radiation Therapy for GBM | completed | N/A | 23 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Jul 8, 2026 | clinicaltrials |
| NCT04573816 | Development of a Tele-monitoring Program for Patients Undergoing Surgery for Pheochromocytoma and / or Paraganglioma(e-PPGL) | completed | — | 132 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jul 8, 2026 | clinicaltrials |
| NCT05698199 | Study to Evaluate the Safety, Tolerability, Immunogenicity and Preliminary Efficacy of ITI-1001 In Patients With Newly Diagnosed Glioblastoma (GBM) | completed | Phase 1 | 10 | Immunomic Therapeutics, Inc.INDUSTRY | 1 | Jul 1, 2026 | clinicaltrials |
| NCT06368310 | FIH Clinical Investigation of Graphene Electrodes for Brain Mapping | completed | N/A | 10 | University of ManchesterOTHER | 1 | Jun 30, 2026 | clinicaltrials |
| NCT05326464 | Tofacitinib in Recurrent GBM Patients | completed | Phase 3 | 18 | University of Texas Southwestern Medical CenterOTHER | 1 | Jun 29, 2026 | clinicaltrials |
| NCT07673666 | GliomaAI-Astro23: MRI-Based Detection of IDH Mutant Astrocytoma (Grade 2 and 3)(GliomaAI-A23) | completed | — | 1,372 | Deep Learning Institute of Radiological SciencesOTHER | 1 | Jun 29, 2026 | clinicaltrials |
| NCT07673679 | GliomaAI-Astro4: MRI-Based Detection of IDH Mutant Astrocytoma Grade 4(GliomaAI-A4) | completed | — | 1,372 | Deep Learning Institute of Radiological SciencesOTHER | 1 | Jun 29, 2026 | clinicaltrials |
| NCT07673692 | GliomaAI-GBM: MRI-Based Detection of IDH Wildtype Glioblastoma(GliomaAI-GBM) | completed | — | 1,372 | Deep Learning Institute of Radiological SciencesOTHER | 1 | Jun 29, 2026 | clinicaltrials |
| NCT07673705 | GliomaAI-Oligo: MRI-Based Detection of IDH Mutant Oligodendroglioma(GliomaAI-Oligo) | completed | — | 1,372 | Deep Learning Institute of Radiological SciencesOTHER | 1 | Jun 29, 2026 | clinicaltrials |
| NCT00209989 | Phase II Trial to Assess the Radiosensitizing Effect of ZARNESTRA in Patients With Glioblastoma Multiforme | completed | Phase 2 | 27 | Institut Claudius RegaudOTHER | 1 | Jun 26, 2026 | clinicaltrials |
| NCT02303678 | D2C7 for Adult Patients With Recurrent Malignant Glioma | completed | Phase 1 | 81 | Darell BignerOTHER | 1 | Jun 26, 2026 | clinicaltrials |
| NCT07198087 | A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants | completed | Phase 1 | 40 | Ono Pharmaceutical Co., Ltd.INDUSTRY | 1 | Jun 26, 2026 | clinicaltrials |
| NCT00308165 | Topotecan by Intracerebral Clysis for Recurrent Primary Malignant Brain Tumors | completed | Phase 1 | 16 | Columbia UniversityOTHER | 1 | Jun 25, 2026 | clinicaltrials |
| NCT04469244 | Evaluation of the Use of Radiomics in 18F-FDOPA PET Examinations for the Characterization of Gliomas(RADDOPAG) | completed | — | 1,000 | Central Hospital, Nancy, FranceOTHER | 1 | Jun 25, 2026 | clinicaltrials |
| NCT07017790 | Amino Acid PET to Assess the Efficacy of IDH Inhibitor Treatments for IDH Mutated Gliomas(TEP-IDH) | completed | — | 22 | Central Hospital, Nancy, FranceOTHER | 1 | Jun 25, 2026 | clinicaltrials |
| NCT07664254 | GliomaAI-MG: MRI-Based Detection of Molecular Glioblastoma(GliomaAI-MG) | completed | — | 1,372 | Deep Learning Institute of Radiological SciencesOTHER | 1 | Jun 24, 2026 | clinicaltrials |
| NCT03194906 | Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors | completed | Phase 2 | 41 | St. Jude Children's Research HospitalOTHER | 1 | Jun 23, 2026 | clinicaltrials |
| NCT05644080 | 68Ga/177Lu-PSMA Theranostics in Recurrent Grade 3 and Grade 4 Glioma | completed | N/A | 10 | St. Olavs HospitalOTHER | 1 | Jun 18, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 | clinicaltrials |
| NCT07651020 | The Clinical Application Value of SPECT Imaging Targeting LRRC15 in Malignant Tumors | completed | — | 1 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jun 16, 2026 | clinicaltrials |
| NCT03115164 | Astrocytoma / Desmoplastic Gamliogliomes (DIA / DIG) - Study of the French Cohort of the Last 20 Years : Clinical, Anatomopathological, Molecular and Radiological Charactersics(DIA/DIG) | completed | — | 37 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Jun 15, 2026 | clinicaltrials |
| NCT04916015 | Histomolecular Profiles of Gliomas in Children and Adolescent/Young Adults(BioMol GLIOMA) | completed | — | 128 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Jun 15, 2026 | clinicaltrials |
| NCT04479514 | Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy | completed | Phase 2 | 14 | Dana-Farber Cancer InstituteOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT03557359 | Nivolumab for Recurrent or Progressive IDH Mutant Gliomas | completed | Phase 2 | 35 | Fabio Iwamoto, MDOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT04458935 | Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma | completed | — | 25 | National Eye Institute (NEI)NIH | 1 | Jun 10, 2026 | clinicaltrials |
| NCT00085735 | Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma | completed | Phase 3 | 549 | Children's Oncology GroupNETWORK | 7 | Jun 9, 2026 | clinicaltrials |
| NCT04128306 | Brain Areas of Time-To-Contact Perception: an Awake Surgery Study(BRAIN-TIME) | completed | N/A | 120 | University Hospital, ToulouseOTHER | 1 | Jun 9, 2026 | clinicaltrials |
| NCT07635173 | SM-1 Combined With Temozolomide in Subjects With Refractory or Recurrent High-Grade Gliomas | completed | Phase 1 | 35 | Shenzhen Zhenxing Medical Technology Co., LtdOTHER | 1 | Jun 9, 2026 | clinicaltrials |
| NCT00392327 | Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET | completed | Phase 3 | 379 | Children's Oncology GroupNETWORK | 5 | Jun 8, 2026 | clinicaltrials |
| NCT04911621 | Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma(ADDICT-pedGLIO) | completed | Phase 1 / Phase 2 | 10 | University Hospital, AntwerpOTHER | 1 | Jun 5, 2026 | clinicaltrials |
| NCT05937776 | Developing a New Metabolic Imaging Approach (aMRI) for Evaluating Neurological Disease in Patients With Gliomas | completed | — | 4 | OHSU Knight Cancer InstituteOTHER | 1 | Jun 5, 2026 | clinicaltrials |
| NCT03514069 | Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma | completed | Phase 1 | 60 | Case Comprehensive Cancer CenterOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT03975959 | Memory Perception Assessment in Central/Non-central Nervous System Cancers(PROMESSE) | completed | N/A | 426 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT05186064 | Glioblastoma Targeted Treatment Option Maximization by WGS(GLOW) | completed | N/A | 164 | UMC UtrechtOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT02883049 | Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations | completed | Phase 3 | 5,949 | National Cancer Institute (NCI)NIH | 7 | Jun 2, 2026 | clinicaltrials |
Data updated 22 days agoSource updated Aug 6, 2026source: clinicaltrials