Cancer Family
Nervous System Neoplasm
CI-CAN-00000038Explore in graph →
Non-malignant1,523 active trials9 approved drugs210 evidence items
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Cancer Family
CI-CAN-00000038Explore in graph →
Clinical trials
5,871 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06325683 | Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma | suspended | Phase 2 | 184 | National Cancer Institute (NCI)NIH | 1 | Sep 29, 2026 | clinicaltrials |
| NCT07708961 | Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma | suspended | Phase 2 | 60 | Mayo ClinicOTHER | 1 | Sep 23, 2026 | clinicaltrials |
| NCT06129760 | Glioblastoma Remote Monitoring and Care - Research Protocol | suspended | N/A | 25 | Case Comprehensive Cancer CenterOTHER | 1 | Sep 15, 2026 | clinicaltrials |
| NCT06639607 | PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma(PRiME II) | suspended | Phase 1 / Phase 2 | 68 | Washington University School of MedicineOTHER | 1 | Sep 11, 2026 | clinicaltrials |
| NCT06329570 | Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) | suspended | Phase 1 / Phase 2 | 10 | NaviFUS CorporationINDUSTRY | 1 | Sep 9, 2026 | clinicaltrials |
| NCT03952598 | Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy | suspended | Phase 2 | 42 | National Cancer Institute (NCI)NIH | 1 | Sep 8, 2026 | clinicaltrials |
| NCT05607407 | Methimazole in Patients With Progressive Glioblastoma | suspended | Phase 2 | 19 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 17, 2026 | clinicaltrials |
| NCT04539366 | Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, GD2-CAR PERSIST Trial | suspended | Phase 1 | 73 | National Cancer Institute (NCI)NIH | 1 | Aug 5, 2026 | clinicaltrials |
| NCT04810871 | Surgical Resection of Latent Brain Tumors Prior to Recurrence | suspended | N/A | 40 | Mayo ClinicOTHER | 1 | Aug 5, 2026 | clinicaltrials |
| NCT06922604 | Glofitamab With Obinutuzumab Pre-treatment for the Treatment of Central Nervous System Lymphoma | suspended | Phase 1 | 20 | City of Hope Medical CenterOTHER | 1 | Jul 6, 2026 | clinicaltrials |
| NCT06169280 | Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma | suspended | Phase 1 | 20 | Northwestern UniversityOTHER | 1 | Jun 30, 2026 | clinicaltrials |
| NCT05695976 | GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM | suspended | — | 100 | Duke UniversityOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT01083966 | Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Vestibular Schwannoma | suspended | Phase 1 | 30 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT01386710 | Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma | suspended | Phase 1 / Phase 2 | 54 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT04222309 | Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) | suspended | Phase 1 | 10 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT05513859 | Investigational Imaging Technique During Brain Surgery | suspended | N/A | 24 | Emory UniversityOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT05887882 | Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Pediatric Brain Tumors(PNOC028) | suspended | Phase 1 | 24 | Sabine Mueller, MD, PhDOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT05428852 | Keto-Brain:Investigating the Use of Ketogenic Diets in Brain Metastases | suspended | N/A | 24 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT04309552 | Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma | suspended | Phase 1 | 8 | Weill Medical College of Cornell UniversityOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT07353229 | 68Ga-Dotatate PET and MRI Guided Radiation Dose Escalation for High Risk Meningioma | suspended | Phase 1 | 24 | Thomas Jefferson UniversityOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT06355908 | IL13Rα2 CAR-T for Patients With r/r Glioma(ENHANCING) | suspended | Phase 1 | 30 | Yang ZhangOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT04657146 | Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma(LAMB-G) | suspended | — | 40 | Duke UniversityOTHER | 1 | Nov 12, 2025 | clinicaltrials |
| NCT06855628 | Assessment of Novel Metabolic Imaging Modalities as A Predictor Of Therapeutic EfficacyiIn Glioblastoma (GBM) | suspended | Phase 2 | 10 | Stanford UniversityOTHER | 1 | Oct 28, 2025 | clinicaltrials |
| NCT02742883 | A Study of Atengenal and Astugenal in Diffuse, Intrinsic Pontine Glioma (DIPG) | suspended | Phase 2 | 1 | Burzynski Research InstituteOTHER | 1 | Sep 16, 2025 | clinicaltrials |
| NCT05475522 | Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases(SONOFLUO) | suspended | N/A | 134 | Sklifosovsky Institute of Emergency CareOTHER_GOV | 1 | May 16, 2025 | clinicaltrials |
| NCT05484219 | Functional Navigation in Surgery of Cerebral Tumors and Vascular Malformations(FUN) | suspended | N/A | 50 | Sklifosovsky Institute of Emergency CareOTHER_GOV | 1 | May 16, 2025 | clinicaltrials |
| NCT05485038 | General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas(GAMMA) | suspended | N/A | 72 | Sklifosovsky Institute of Emergency CareOTHER_GOV | 1 | May 16, 2025 | clinicaltrials |
| NCT05123534 | A Phase 2 Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPG | suspended | Phase 2 | 15 | SonALAsense, Inc.INDUSTRY | 1 | Sep 19, 2024 | clinicaltrials |
| NCT02546102 | Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma | suspended | Phase 3 | 234 | Precision Life Sciences GroupINDUSTRY | 3 | Apr 3, 2024 | clinicaltrials |
| NCT03055208 | Early Stereotactic Gamma Knife Radiosurgery to Residual Tumor After Surgery of Newly Diagnosed Glioblastoma(Gamma-GBM) | suspended | N/A | 50 | Universitätsmedizin MannheimOTHER | 1 | May 11, 2023 | clinicaltrials |
| NCT01933815 | Dose-Escalation Study of TPI 287 + Avastin Followed by Randomized Study of the Same Versus Avastin for Glioblastoma | suspended | Phase 1 / Phase 2 | 92 | Cortice Biosciences, Inc.INDUSTRY | 1 | Feb 22, 2023 | clinicaltrials |
| NCT04209023 | The Use of Navigated Transcranial Magnetic Stimulation (nTMS) in the Inhibition of Neurofunctional Regions of Interest | suspended | N/A | 10 | Neurological Associates of West Los AngelesOTHER | 1 | Sep 28, 2022 | clinicaltrials |
| NCT04285697 | Infection Prevention Bundle in Brain Tumor Surgery | suspended | N/A | 300 | Istanbul University - CerrahpasaOTHER | 1 | Aug 4, 2022 | clinicaltrials |
| NCT03322813 | ExAblate Blood Brain Barrier Disruption (BBBD) for Planned Surgery in Suspected Infiltrating Glioma | suspended | N/A | 15 | InSightecINDUSTRY | 1 | Aug 3, 2022 | clinicaltrials |
| NCT04219475 | Predicting Response Patterns to Treatment in Glioblastoma (GBM) Patients(PROPHETIC) | suspended | — | 1,000 | OncoHost Ltd.INDUSTRY | 1 | Apr 19, 2022 | clinicaltrials |
| NCT03334162 | Playful Sensorimotor Training in Pediatric Brain Tumor Patients(RESET) | suspended | N/A | 20 | University of BaselOTHER | 1 | Apr 19, 2019 | clinicaltrials |
| NCT02773888 | An Evaluation of Non-Invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an Intraparenchymal Pressure Monitoring Device | suspended | N/A | 80 | HeadSense MedicalINDUSTRY | 1 | Feb 27, 2017 | clinicaltrials |
| NCT00909558 | Safety and Effectiveness Study of Autologous Natural Killer and Natural Killer T Cells on Cancer | suspended | Phase 1 | 24 | Envita Medical Center, Inc.INDUSTRY | 1 | Feb 24, 2010 | clinicaltrials |
Data updated 11 hours agoSource updated Sep 29, 2026source: clinicaltrials