Clinical trial · Interventional
Brain Areas of Time-To-Contact Perception: an Awake Surgery Study
Localizing in the Brain the Areas of Time to Contact Perception During an Awake Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
During a brain surgery targeted to remove a brain tumor, the neurosurgeon wakes up the patient to delimit the tumor area exactly, and identify the surrounding areas, to limit the surgery damages. The present project aims at testing the patient in this awake phase to determine the brain areas implied in time to contact (TTC) perception, a function that allows determining the arrival time of moving objects and used in many tasks of our daily life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumors | Brain Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Awake surgery | Procedure | — | UNRESOLVED |
| Behavioral task | Behavioral | — | UNRESOLVED |
| Neurological assessment | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Patient group
- description
- A total of 120 patients with brain tumors will be divided into our two groups, divided as follows: 1. In the group Pre-Per, 20 patients will be included by localization of electrical stimulation (60 patients in total). A patient who would be stimulable in two different areas could be included in two different groups. 2. In the group Pre-End, the subjects will be distributed by localization of the brain tumor, by lobe. A total of 20 participants will be included per lobe, corresponding to the frontal, temporal or parietal lobes (as a reminder, a tumor in the occipital lobe is an exclusion criterion), for a total of 60 participants
- interventionNames
- Behavioral: Behavioral task
- Procedure: Awake surgery
- Other: Neurological assessment
- type
- ACTIVE_COMPARATOR
- label
- Control group
- description
- A maximum of 120 healthy matched sex and age subjects with patients will also be included
- interventionNames
- Behavioral: Behavioral task
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: For the patients: * Brain tumor that does not affect the dominant hand motricity. The patient that have a tumor in an area targeted for a cortical stimulation will be automatically enrolled within the Pre-End group. * Who will agree with all terms and sign the experimental agreement * Correct or corrected vision, as allowed by the surgery constraints * With no known oculomotor abnormalities (list of exclusion in Annexe) * Affiliated to a social security system For the control group: * Who will agree with all terms and sign the experimental agreement * Correct or corrected vision * With no known oculomotor abnormalities. * Affiliated to a social security system Exclusion Criteria: For the patients: * Brain tumor located in the occipital area * Legally protected patient, or with unknown ability to sign the experimental agreement, as determined by the medical team. * Medical background of neurological diseases of the central nervous system, as Parkinson, Alzheimer, stroke * Pregnancy For the control group: * Legally protected patient, or with unknown ability to sign the experimental agreement, as determined by the medical team. * Medical background of neurological diseases of the central nervous system, as Parkinson, Alzheimer, stroke * Pregnancy
References
Publications (0)
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