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Clinical trials
218 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00314119 | Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1 | completed | — | 17 | National Cancer Institute (NCI)NIH | 1 | Sep 28, 2026 | clinicaltrials |
| NCT07801560 | CyberKnife Radiotherapy for the Treatment of Schwannomas(Schwannomas) | completed | — | 200 | Hartmann Oncology Radiotherapy Group, FranceOTHER | 1 | Sep 9, 2026 |
| clinicaltrials |
| NCT02211768 | Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1 | completed | Phase 1 | 10 | National Cancer Institute (NCI)NIH | 1 | Aug 4, 2026 | clinicaltrials |
| NCT04465643 | Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor | completed | Phase 1 | 13 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jul 10, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 | clinicaltrials |
| NCT03433183 | SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors | completed | Phase 2 | 21 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT04283669 | Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas(NF110) | completed | Phase 2 | 12 | University of Alabama at BirminghamOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT05005845 | NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) | completed | Phase 2 | 199 | NFlection Therapeutics, Inc.INDUSTRY | 1 | Feb 17, 2026 | clinicaltrials |
| NCT05786144 | Vestibular Schwannoma Organoids | completed | — | 100 | Maastricht Radiation OncologyOTHER | 1 | Jan 30, 2026 | clinicaltrials |
| NCT06322342 | Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent | completed | Phase 2 | 18 | Reveal Pharmaceuticals Inc.INDUSTRY | 1 | Dec 26, 2025 | clinicaltrials |
| NCT07305285 | Roy Adaptation Model Improves Mood and QOL After Giant Acoustic Neuroma | completed | N/A | 160 | West China HospitalOTHER | 1 | Dec 26, 2025 | clinicaltrials |
| NCT03406208 | Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing | completed | N/A | 228 | Massachusetts General HospitalOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT04057976 | Use of DTT to Define Facial Nerve Position in Vestibular Schwannomas | completed | N/A | 38 | King's College Hospital NHS TrustOTHER | 1 | Sep 12, 2025 | clinicaltrials |
| NCT04811196 | A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients | completed | Phase 1 | 56 | University Health Network, TorontoOTHER | 1 | May 29, 2025 | clinicaltrials |
| NCT03231306 | Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas(NF108-BINI) | completed | Phase 2 | 45 | University of Alabama at BirminghamOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT02249572 | Vestibular Schwannoma - Radiosurgery or Expectation: V-REX.(V-REX) | completed | N/A | 100 | Haukeland University HospitalOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT04730583 | Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas | completed | Phase 1 | 34 | Massachusetts General HospitalOTHER | 1 | Feb 21, 2025 | clinicaltrials |
| NCT02700230 | Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery | completed | Phase 1 | 9 | Mayo ClinicOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT03531814 | Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1(NF1) on Clinical Treatment Trials | completed | N/A | 12 | National Cancer Institute (NCI)NIH | 1 | Jun 11, 2024 | clinicaltrials |
| NCT05438290 | DPCP to Treat Cutaneous Neurofibromas Associated With NF1 | completed | Phase 1 | 17 | Nicholas GulatiOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT04241679 | Auditory Nerve Test System During Vestibular Schwannoma Resection(ANTS) | completed | N/A | 10 | Washington University School of MedicineOTHER | 1 | Apr 25, 2024 | clinicaltrials |
| NCT01938677 | Gamma Knife Radiosurgery vs Initial Conservative Treatment for Vestibular Schwannoma Patients With Preserved Hearing, a Prospective Randomized Study | completed | N/A | 67 | Karolinska InstitutetOTHER | 1 | Apr 18, 2024 | clinicaltrials |
| NCT03326388 | Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours(INSPECT) | completed | Phase 1 / Phase 2 | 14 | Great Ormond Street Hospital for Children NHS Foundation TrustOTHER | 1 | Apr 4, 2024 | clinicaltrials |
| NCT02839720 | Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma | completed | Phase 2 | 11 | National Cancer Institute (NCI)NIH | 1 | Dec 6, 2023 | clinicaltrials |
| NCT02584309 | Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma | completed | Phase 2 | 73 | Washington University School of MedicineOTHER | 1 | Nov 7, 2023 | clinicaltrials |
| NCT03009201 | Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery | completed | Phase 1 | 16 | OHSU Knight Cancer InstituteOTHER | 1 | Aug 16, 2023 | clinicaltrials |
| NCT04351373 | Microscopic Fluorescence-guided Vestibular Schwannoma Resection Using Fluorescein Sodium and YELLOW 560 | completed | Phase 2 | 12 | Mayo ClinicOTHER | 1 | Aug 1, 2023 | clinicaltrials |
| NCT03581331 | Consequence of Unilateral Vestibular Loss on Visual Abilities(SVorthoptie) | completed | N/A | 20 | Assistance Publique Hopitaux De MarseilleOTHER | 1 | Jul 14, 2023 | clinicaltrials |
| NCT03958006 | Simultaneous Cochlear Implantation During Translabyrinthine Resection of Vestibular Schwannoma | completed | N/A | 6 | Henry Ford Health SystemOTHER | 1 | Apr 20, 2023 | clinicaltrials |
| NCT03542773 | Targeted Imaging of Glutamate Carboxypeptidase II With DCFPyL-PET | completed | Phase 1 | 38 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT03666507 | Vegetative Monitoring During Brainstem-associated Surgery | completed | — | 103 | University Hospital TuebingenOTHER | 1 | Nov 4, 2022 | clinicaltrials |
| NCT04658836 | Triamcinolone Levels in Cochlear Perilymph, Lateral Canal and CSF | completed | Phase 1 | 21 | Medical University of ViennaOTHER | 1 | Aug 24, 2022 | clinicaltrials |
| NCT04435665 | NFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) | completed | Phase 2 | 48 | NFlection Therapeutics, Inc.INDUSTRY | 1 | Aug 9, 2022 | clinicaltrials |
| NCT01129687 | Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy | completed | — | 157 | Stanford UniversityOTHER | 1 | May 10, 2022 | clinicaltrials |
| NCT00346164 | Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma | completed | Phase 3 | 588 | Children's Oncology GroupNETWORK | 5 | Apr 28, 2022 | clinicaltrials |
| NCT02452554 | Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma | completed | Phase 2 | 62 | Children's Oncology GroupNETWORK | 1 | Jan 13, 2022 | clinicaltrials |
| NCT02948790 | Auditory Nerve Monitoring Using Intra-cochlear Stimulation in Subjects With Acoustic Neuroma(NeuriStim) | completed | N/A | 17 | Oticon MedicalINDUSTRY | 1 | Oct 20, 2021 | clinicaltrials |
| NCT01532687 | Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma | completed | Phase 2 | 54 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT02934256 | Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors(Icotinib) | completed | Phase 2 | 10 | Li PengOTHER | 1 | Sep 9, 2021 | clinicaltrials |
| NCT01800032 | PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1) | completed | — | 30 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | May 12, 2021 | clinicaltrials |
| NCT01125046 | Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas | completed | Phase 2 | 50 | Northwestern UniversityOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT00863122 | Concentration and Activity of Lapatinib in Vestibular Schwannomas | completed | Early Phase 1 | 26 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jan 12, 2021 | clinicaltrials |
| NCT01347307 | Stereotactic Body Radiotherapy for Spine Tumors | completed | N/A | 38 | Mercy ResearchOTHER | 1 | Jun 18, 2020 | clinicaltrials |
| NCT00727233 | Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas | completed | Phase 1 | 9 | National Cancer Institute (NCI)NIH | 1 | Dec 12, 2019 | clinicaltrials |
| NCT00004853 | Comparison of Filgrastim and Filgrastim SD/01in Boosting White Cell Counts After Intensive Chemotherapy | completed | Phase 1 | 34 | National Cancer Institute (NCI)NIH | 1 | Nov 12, 2019 | clinicaltrials |
| NCT02008877 | SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors) | completed | Phase 1 / Phase 2 | 20 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | May 15, 2019 | clinicaltrials |
| NCT01661283 | SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors | completed | Phase 2 | 25 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Mar 6, 2019 | clinicaltrials |
| NCT02309099 | Cochlear Implantation After Labyrinthectomy or a Translabyrinthine Surgical Approach | completed | N/A | 10 | University of North Carolina, Chapel HillOTHER | 1 | Jan 7, 2019 | clinicaltrials |
| NCT01614795 | Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma | completed | Phase 2 | 46 | National Cancer Institute (NCI)NIH | 2 | Dec 11, 2018 | clinicaltrials |
| NCT00464620 | Trial of Dasatinib in Advanced Sarcomas | completed | Phase 2 | 366 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Nov 23, 2018 | clinicaltrials |
Data updated 2 days agoSource updated Sep 28, 2026source: clinicaltrials