Clinical trial · Observational
Vestibular Schwannoma Organoids
Vestibular Schwannoma Stem Cell Organoids
NCT05786144CI-TRIAL-00102064completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In standard of care regularly planned surgery, tissue will be obtained from patients who are suspicious for having vestibular Schwannoma (on MRI). The tissue that remains after the pathologist gathered sufficient for analysis, the remaining tissue is used for creating tumour stem cell organoids.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Vestibular Schwannoma | Vestibular Schwannoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Feasibility
- timeFrame
- 10 years
- description
- Feasibility to create organoids from schwannoma tumour tissue and make a "living" biobank of these tissues in the laboratory to study the resistance mechanisms towards treatments.
Secondary outcomes (5)
- measure
- Phenotype
- timeFrame
- 10 years
- description
- Comparing the phenotypical profile of the vestibular schwannoma organoid to the phenotypical profile of the original tumour.
- measure
- Genetic
- timeFrame
- 10 years
- description
- Comparing the genetic profile of the vestibular schwannoma organoid to the genetic profile of the original tumour.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * MRI with suspicion for vestibular schwannoma * Indication for surgery in the skull base committee * 18 years or older Exclusion Criteria: * Refusal to participate * Younger than 18 years * Incapacitated
References
Publications (0)
Data not yet available
No reference posted for this study.