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Clinical trials
218 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05985161 | A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors | recruiting | Phase 2 | 45 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 6, 2026 | clinicaltrials |
| NCT04483778 | B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults | active not recruiting | Phase 1 | 68 | Seattle Children's HospitalOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT03363217 |
| Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway. |
| active not recruiting |
| Phase 2 |
| 114 |
| St. Justine's HospitalOTHER |
| 1 |
| Apr 24, 2026 |
| clinicaltrials |
| NCT06300502 | Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs) | enrolling by invitation | Phase 1 | 15 | Massachusetts General HospitalOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT06638931 | Agnostic Therapy in Rare Solid Tumors(ANTARES) | recruiting | Phase 2 | 28 | Instituto do Cancer do Estado de São PauloOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT06159166 | Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).(Mirda) | recruiting | Phase 1 / Phase 2 | 24 | Johns Hopkins UniversityOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT06517888 | Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma | recruiting | Phase 1 / Phase 2 | 27 | Akouos, Inc.INDUSTRY | 1 | Apr 6, 2026 | clinicaltrials |
| NCT05702749 | Evaluating Pre-Treatment Vestibular Physical Therapy Rehab for Patients With Vestibular Schwannomas(VS PREHAB) | recruiting | N/A | 36 | Medical College of WisconsinOTHER | 1 | Mar 24, 2026 | clinicaltrials |
| NCT04924608 | Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas(KOMET) | active not recruiting | Phase 3 | 145 | AstraZenecaINDUSTRY | 13 | Mar 23, 2026 | clinicaltrials |
| NCT04283669 | Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas(NF110) | completed | Phase 2 | 12 | University of Alabama at BirminghamOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT04420975 | Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma | active not recruiting | Phase 1 | 14 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT03141021 | Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors | recruiting | — | 1,050 | Washington University School of MedicineOTHER | 5 | Mar 9, 2026 | clinicaltrials |
| NCT04091295 | BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast | available | — | — | Aveni FoundationOTHER | 1 | Mar 4, 2026 | clinicaltrials |
| NCT04278118 | Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study(HiPPI) | recruiting | N/A | 70 | Emory UniversityOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT05005845 | NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) | completed | Phase 2 | 199 | NFlection Therapeutics, Inc.INDUSTRY | 1 | Feb 17, 2026 | clinicaltrials |
| NCT05139277 | Evaluation of the CONVIVO System | recruiting | N/A | 30 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT04872543 | A Study of ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST) | recruiting | Phase 2 | 25 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT05786144 | Vestibular Schwannoma Organoids | completed | — | 100 | Maastricht Radiation OncologyOTHER | 1 | Jan 30, 2026 | clinicaltrials |
| NCT07364955 | Vestibular Rehabilitation Protocol in Unilateral Vestibular Schwannoma | recruiting | N/A | 75 | Albert Torrents TorreroOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT06163664 | Role of ChatGPT in Vestibular Schwannoma Management | withdrawn | N/A | 0 | University of Southern CaliforniaOTHER | 0 | Jan 13, 2026 | clinicaltrials |
| NCT05677594 | Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1 | active not recruiting | — | 80 | Johns Hopkins UniversityOTHER | 1 | Jan 12, 2026 | clinicaltrials |
| NCT06849986 | IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)(TAIS) | recruiting | Phase 2 | 45 | Fudan UniversityOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT06322342 | Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent | completed | Phase 2 | 18 | Reveal Pharmaceuticals Inc.INDUSTRY | 1 | Dec 26, 2025 | clinicaltrials |
| NCT07305285 | Roy Adaptation Model Improves Mood and QOL After Giant Acoustic Neuroma | completed | N/A | 160 | West China HospitalOTHER | 1 | Dec 26, 2025 | clinicaltrials |
| NCT03406208 | Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing | completed | N/A | 228 | Massachusetts General HospitalOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT03261726 | Maintaining Cochlear Patency After VIIIth Nerve Surgery | withdrawn | N/A | 0 | Henry Ford Health SystemOTHER | 1 | Dec 19, 2025 | clinicaltrials |
| NCT03079999 | Study of Aspirin in Patients With Vestibular Schwannoma | active not recruiting | Phase 2 | 97 | Massachusetts Eye and Ear InfirmaryOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT02282917 | Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma | terminated | Early Phase 1 | 7 | Massachusetts Eye and Ear InfirmaryOTHER | 1 | Dec 5, 2025 | clinicaltrials |
| NCT06961565 | PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas | recruiting | Phase 1 | 56 | Pasithea Therapeutics Corp.INDUSTRY | 3 | Dec 4, 2025 | clinicaltrials |
| NCT03618381 | EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults | active not recruiting | Phase 1 | 44 | Seattle Children's HospitalOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT05581511 | Natural History Study of Cutaneous Neurofibromas in People With NF1(cNF Natural Hx) | active not recruiting | — | 500 | Johns Hopkins UniversityOTHER | 1 | Oct 14, 2025 | clinicaltrials |
| NCT04057976 | Use of DTT to Define Facial Nerve Position in Vestibular Schwannomas | completed | N/A | 38 | King's College Hospital NHS TrustOTHER | 1 | Sep 12, 2025 | clinicaltrials |
| NCT07130851 | Mapping of Vestibular Centers Activation Using fMRI in Patients With Vestibular Schwannoma | active not recruiting | N/A | 40 | Marketa BonaventurovaOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT07116811 | Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients(SAF-NRVS) | not yet recruiting | Phase 3 | 364 | Beijing Tiantan HospitalOTHER | 1 | Aug 12, 2025 | clinicaltrials |
| NCT03611868 | A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors | active not recruiting | Phase 1 / Phase 2 | 230 | Ascentage Pharma Group Inc.INDUSTRY | 2 | Aug 7, 2025 | clinicaltrials |
| NCT07078136 | Multicenter Observational Study of Multimodal AI for Upper GI Mesenchymal Tumor Diagnosis | recruiting | — | 130 | Huazhong University of Science and TechnologyOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT06553365 | Phase II Study of FCN-159 in NF2 Nerve Sheath Tumors | recruiting | Phase 2 | 30 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT06277154 | MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma | recruiting | Phase 2 | 148 | HRYZ Biotech Co.INDUSTRY | 1 | Jul 24, 2025 | clinicaltrials |
| NCT04530487 | Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults | terminated | Phase 2 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 29, 2025 | clinicaltrials |
| NCT07024394 | Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1 | not yet recruiting | Phase 1 / Phase 2 | 65 | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.INDUSTRY | 1 | Jun 17, 2025 | clinicaltrials |
| NCT04811196 | A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients | completed | Phase 1 | 56 | University Health Network, TorontoOTHER | 1 | May 29, 2025 | clinicaltrials |
| NCT06660082 | Early Rehabilitation Using Head Impulse Test for Acute Vestibular Deficit(KINE HIT) | recruiting | N/A | 26 | Hospices Civils de LyonOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT03231306 | Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas(NF108-BINI) | completed | Phase 2 | 45 | University of Alabama at BirminghamOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT03095248 | Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors(SEL-TH-1601) | terminated | Phase 2 | 10 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Apr 22, 2025 | clinicaltrials |
| NCT04196933 | Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma | withdrawn | N/A | 0 | Massachusetts Eye and Ear InfirmaryOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT02249572 | Vestibular Schwannoma - Radiosurgery or Expectation: V-REX.(V-REX) | completed | N/A | 100 | Haukeland University HospitalOTHER | 1 | Apr 2, 2025 | clinicaltrials |
| NCT02584647 | PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors(PLX3397) | terminated | Phase 1 / Phase 2 | 39 | Gulam ManjiOTHER | 1 | Mar 21, 2025 | clinicaltrials |
| NCT04594057 | Longitudinal Recovery of Laboratory, Clinical, and Community-Based Measures of Head and Trunk Control in People With Acquired Vestibulopathy | terminated | N/A | 10 | University of UtahOTHER | 1 | Mar 19, 2025 | clinicaltrials |
| NCT05913037 | FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas | active not recruiting | Phase 3 | 167 | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.INDUSTRY | 1 | Mar 6, 2025 | clinicaltrials |
| NCT06844461 | Quality of Life and Decisional Regret in Patients Affected by Acoustic Neuroma(QOL-DR-NEUROMA) | recruiting | — | 40 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Feb 25, 2025 | clinicaltrials |
Data updated 23 days agoSource updated May 6, 2026source: clinicaltrials