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CancerIndexthe global index of cancer

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

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CancerIndex

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Neoplasm by Special Category — Research · CancerIndex

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Neoplasm
Neoplasm by Special Category

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Neoplasm by Special Category

CI-CAN-00000004Explore in graph →

Non-malignant21,361 active trials259 approved drugs3,860 evidence items

NCIt: C7062

Overview
Statistics
Survival
Genomics536
Variants & evidence3860
Drugs429
Trials95753
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (4,615)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 4,201–4,225 of 4,615 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Class III β-tubulin counteracts the ability of paclitaxel to inhibit cell migration.
· Oncotarget · 2011 · PMID 21576762 · validated civic_curation pubmed
Phase II study of everolimus with biomarker exploration in patients with advanced gastric cancer refractory to chemotherapy including fluoropyrimidine and platinum.
· Br J Cancer · 2012 · PMID 22343617 · validated civic_curation pubmed
mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors.
· Cell Cycle · 2012 · PMID 22262166 · validated civic_curation pubmed
BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma.
· J Pathol · 2012 · PMID 22190288 · validated civic_curation pubmed
Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma.
· J Cell Mol Med · 2012 · PMID 22004109 · validated civic_curation pubmed
C609T polymorphism of NAD(P)H quinone oxidoreductase 1 as a predictive biomarker for response to amrubicin.
· J Thorac Oncol · 2011 · PMID 21964527 · validated civic_curation pubmed
Toll-like receptor 9 agonist IMO cooperates with cetuximab in K-ras mutant colorectal and pancreatic cancers.
· Clin Cancer Res · 2011 · PMID 21890455 · validated civic_curation pubmed

Showing 4,201–4,225 of 4,615 publications

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ATP-binding cassette B1 gene polymorphisms, mRNA expression and chemosensitivity to paclitaxel in non-small cell lung cancer cells.

· Respirology · 2011 · PMID 21883677 · validated civic_curation pubmed

Establishment of six new human biliary tract carcinoma cell lines and identification of MAGEH1 as a candidate biomarker for predicting the efficacy of gemcitabine treatment.

· Cancer Sci · 2010 · PMID 20088962 · validated civic_curation pubmed

Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.

· Mol Cancer Ther · 2006 · PMID 17088436 · validated civic_curation pubmed

OCT4B1 promotes cell growth, migration and invasion suppressing sensitivity to οxaliplatin in colon cancer.

· Oncol Rep · 2015 · PMID 26398480 · validated civic_curation pubmed

Afatinib, an Irreversible EGFR Family Inhibitor, Shows Activity Toward Pancreatic Cancer Cells, Alone and in Combination with Radiotherapy, Independent of KRAS Status.

· Target Oncol · 2016 · PMID 26668065 · validated civic_curation pubmed

In vitro modeling to determine mutation specificity of EGFR tyrosine kinase inhibitors against clinically relevant EGFR mutants in non-small-cell lung cancer.

· Oncotarget · 2015 · PMID 26515464 · validated civic_curation pubmed

NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer.

· Oncotarget · 2016 · PMID 26716414 · validated civic_curation pubmed

Primary cross-resistance to BRAFV600E-, MEK1/2- and PI3K/mTOR-specific inhibitors in BRAF-mutant melanoma cells counteracted by dual pathway blockade.

· Oncotarget · 2016 · PMID 26678033 · validated civic_curation pubmed

Downregulation of cytokeratin 18 is associated with paclitaxel‑resistance and tumor aggressiveness in prostate cancer.

· Int J Oncol · 2016 · PMID 26892177 · validated civic_curation pubmed

Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma.

· Mol Cancer Res · 2014 · PMID 24962318 · validated civic_curation pubmed

Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer.

· J Clin Invest · 2006 · PMID 16906227 · validated civic_curation pubmed

Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors.

· Cancer Res · 2008 · PMID 18451166 · validated civic_curation pubmed

EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer.

· Clin Cancer Res · 2008 · PMID 18594010 · validated civic_curation pubmed

Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants.

· Clin Cancer Res · 2012 · PMID 22912387 · validated civic_curation pubmed

BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells.

· Oncotarget · 2015 · PMID 26397223 · validated civic_curation pubmed

A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity.

· Cancer Discov · 2014 · PMID 24631838 · validated civic_curation pubmed

Overexpression of pRB in human pancreatic carcinoma cells: function in chemotherapy-induced apoptosis.

· J Natl Cancer Inst · 2002 · PMID 11792751 · validated civic_curation pubmed

Crizotinib-resistant mutants of EML4-ALK identified through an accelerated mutagenesis screen.

· Chem Biol Drug Des · 2011 · PMID 22034911 · validated civic_curation pubmed