Myelodysplastic Syndrome — Genomics

Myelodysplastic Syndrome — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

3 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Myelodysplastic (MSK, 2020) mds_mskcc_2020MSK

4,231 cases with simple somatic mutation data · 4,231 cases total · 2026-01-08 · mapped to Myelodysplastic Syndrome EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	DNMT3A	Ssm	853	4,231	20.2%	cbioportal
2	TET2	Ssm	683	4,231	16.1%	cbioportal
3	NPM1	Ssm	674	4,231	15.9%	cbioportal
4	NRAS	Ssm	492	4,231	11.6%	cbioportal
5	FLT3	Ssm	475	4,231	11.2%	cbioportal
6	ASXL1	Ssm	434	4,231	10.3%	cbioportal
7	SRSF2	Ssm	415	4,231	9.8%	cbioportal
8	RUNX1

Data updated 21 days agoSource updated 2026-01-08

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.