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Mesenchymal Cell Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Mesenchymal Cell Neoplasm

Cancer Family

Mesenchymal Cell Neoplasm

CI-CAN-00000027Explore in graph →

Non-malignant413 active trials10 approved drugs208 evidence items

NCIt: C7059

Overview
Statistics
Survival
Genomics12
Variants & evidence208
Drugs20
Trials1848
Research
Rankings
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Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

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Trials tab
Methodology: publication counts

Literature

Linked publications (108)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 76–100 of 108 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Refractory and metastatic infantile fibrosarcoma harboring LMNA-NTRK1 fusion shows complete and durable response to crizotinib.
· Cold Spring Harb Mol Case Stud · 2019 · PMID 30709876 · validated civic_curation pubmed
Recurrent EML4-NTRK3 fusions in infantile fibrosarcoma and congenital mesoblastic nephroma suggest a revised testing strategy.
· Mod Pathol · 2018 · PMID 29099503 · validated civic_curation pubmed
Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteristic ETV6-NTRK3 gene fusion.
· Ann Oncol · 2019 · PMID 32223937 · validated civic_curation pubmed
Characterization of a novel fusion gene EML4-NTRK3 in a case of recurrent congenital fibrosarcoma.
· Cold Spring Harb Mol Case Stud · 2015 · PMID 27148571 · validated civic_curation pubmed
NTRK fusions in osteosarcoma are rare and non-functional events.
· J Pathol Clin Res · 2020 · PMID 32022484 · validated civic_curation pubmed
Recurrent EWSR1-CREB3L1 gene fusions in sclerosing epithelioid fibrosarcoma.
· Am J Surg Pathol · 2014 · PMID 24441665 · validated civic_curation pubmed
A genetic dichotomy between pure sclerosing epithelioid fibrosarcoma (SEF) and hybrid SEF/low-grade fibromyxoid sarcoma: a pathologic and molecular study of 18 cases.
· Genes Chromosomes Cancer · 2015 · PMID 25231134

Showing 76–100 of 108 publications

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· validated civic_curation

COL1A1-PDGFB fusion in a pediatric Bednar tumor with 2 copies of a der(22)t(17;22).

· Cancer Genet Cytogenet · 2006 · PMID 16843106 · validated civic_curation pubmed

Recurrent NCOA2 gene rearrangements in congenital/infantile spindle cell rhabdomyosarcoma.

· Genes Chromosomes Cancer · 2013 · PMID 23463663 · validated civic_curation pubmed

Head and neck rhabdomyosarcoma with TFCP2 fusions and ALK overexpression: a clinicopathological and molecular analysis of 11 cases.

· Histopathology · 2021 · PMID 33382123 · validated civic_curation pubmed

Infantile Rhabdomyosarcomas With VGLL2 Rearrangement Are Not Always an Indolent Disease: A Study of 4 Aggressive Cases With Clinical, Pathologic, Molecular, and Radiologic Findings.

· Am J Surg Pathol · 2021 · PMID 33949344 · validated civic_curation pubmed

Cytogenetic findings in liposarcoma correlate with histopathologic subtypes.

· Cancer · 1992 · PMID 1568170 · validated civic_curation pubmed

CTNNB1 S45F mutation predicts poor efficacy of meloxicam treatment for desmoid tumors: a pilot study.

· PLoS One · 2014 · PMID 24788118 · validated civic_curation pubmed

Infantile Fibrosarcoma With NTRK3-ETV6 Fusion Successfully Treated With the Tropomyosin-Related Kinase Inhibitor LOXO-101.

· Pediatr Blood Cancer · 2016 · PMID 27093299 · validated civic_curation pubmed

FOS-ANKH and FOS-RUNX2 Fusion Genes in Osteoblastoma.

· Cancer Genomics Proteomics · 2020 · PMID 32108038 · validated civic_curation pubmed

Results of sub-analysis of a phase 2 study on trabectedin treatment for extraskeletal myxoid chondrosarcoma and mesenchymal chondrosarcoma.

· BMC Cancer · 2016 · PMID 27418251 · validated civic_curation pubmed

Ponatinib inhibits polyclonal drug-resistant KIT oncoproteins and shows therapeutic potential in heavily pretreated gastrointestinal stromal tumor (GIST) patients.

· Clin Cancer Res · 2014 · PMID 25239608 · validated civic_curation pubmed

Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with imatinib-resistant gastrointestinal stromal tumors.

· Clin Cancer Res · 2012 · PMID 22745105 · validated civic_curation pubmed

The chimeric FUS/TLS-CHOP fusion protein specifically induces liposarcomas in transgenic mice.

· Oncogene · 2000 · PMID 10828883 · validated civic_curation pubmed

Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

· Gastroenterology · 2003 · PMID 12949711 · validated civic_curation pubmed

Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors.

· Cancer Res · 2009 · PMID 19366796 · validated civic_curation pubmed

PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.

· Cancer Discov · 2017 · PMID 28446439 · validated civic_curation pubmed

p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3.

· Mol Cancer Ther · 2007 · PMID 17363498 · validated civic_curation pubmed

A potent combination of the novel PI3K Inhibitor, GDC-0941, with imatinib in gastrointestinal stromal tumor xenografts: long-lasting responses after treatment withdrawal.

· Clin Cancer Res · 2013 · PMID 23231951 · validated civic_curation pubmed

CDKN2A/p16 Loss Implicates CDK4 as a Therapeutic Target in Imatinib-Resistant Dermatofibrosarcoma Protuberans.

· Mol Cancer Ther · 2015 · PMID 25852058 · validated civic_curation pubmed