Publication
CTNNB1 S45F mutation predicts poor efficacy of meloxicam treatment for desmoid tumors: a pilot study.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (4)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 4
- cancerDesmoid Fibromatosiscivic_curation1.00
- drugMeloxicamcivic_curation1.00
- geneCTNNB1civic_curation1.00
- variantCTNNB1 S45Fcivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 24788118
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CTNNB1 S45F1 | ||||||||
| Meloxicam | Desmoid FibromatosisALIAS | Predictive | C | Does Not Support Sensitivity Response | 2 | accepted | EID6049Of the 33 patients with desmoid fibromatosis treated with meloxicam, a COX-2 selective inhibitor, one showed complete remission (CR), 7 partial remission (PR), 12 stable disease (SD), and 13 progressi… (full text at CIViC) PMID 24788118 · Hamada et al., 2014 · Open in CIViC | civic |
| CTNNB1 T41A1 | ||||||||
| Meloxicam | Desmoid FibromatosisALIAS | Predictive | B | Supports Sensitivity Response | 2 | submitted | EID6050Of the 33 patients with desmoid fibromatosis treated with meloxicam, a COX-2 selective inhibitor, one showed complete remission (CR), 7 partial remission (PR), 12 stable disease (SD), and 13 progressi… (full text at CIViC) PMID 24788118 · Hamada et al., 2014 · Open in CIViC | civic |