Skip to content

CancerIndexthe global index of cancer

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Pulse Data updates Year in cancer Taxonomy Countries Compare Trial intelligence Trial map Drug pipeline Sources Methodology About Trust & policies Data downloads Developers (API)

Loading cancer entity…

CancerIndex

CancerIndex is a research and information platform. It is not a physician, does not diagnose, and does not recommend treatment. Population statistics do not predict individual outcomes.

Every number links to its source and retrieval date. Derived metrics carry a formula version. AI-generated synthesis is not enabled in this phase; all content is database-grounded.

About Trust & policies Data explorer Data downloads Pulse Data update log Developers (API)Sources Methodology Taxonomy Countries Compare Contact · contact@spboucher.ai Status

© 2026 CancerIndex · built and maintained by Simon-Pierre Boucher · contact contact@spboucher.ai · hosted on MacLustr (www.maclustr.io). Source data remains under the license of each provider — see /sources.

Melanocytic Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Melanocytic Neoplasm

Cancer Family

Melanocytic Neoplasm

CI-CAN-00000026Explore in graph →

Non-malignant609 active trials13 approved drugs233 evidence items

NCIt: C7058

Overview
Statistics
Survival
Genomics26
Variants & evidence233
Drugs64
Trials3258
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (185)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 151–175 of 185 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

MERTK receptor tyrosine kinase is a therapeutic target in melanoma.
· J Clin Invest · 2013 · PMID 23585477 · validated civic_curation pubmed
Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma.
· Cancer Res · 2015 · PMID 25952648 · validated civic_curation pubmed
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.
· Proc Natl Acad Sci U S A · 2008 · PMID 18287029 · validated civic_curation pubmed
CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations.
· Oncogene · 2009 · PMID 18794803 · validated civic_curation pubmed
Effects of AKT inhibitor therapy in response and resistance to BRAF inhibition in melanoma.
· Mol Cancer · 2014 · PMID 24735930 · validated civic_curation pubmed
Primary cross-resistance to BRAFV600E-, MEK1/2- and PI3K/mTOR-specific inhibitors in BRAF-mutant melanoma cells counteracted by dual pathway blockade.
· Oncotarget · 2016 · PMID 26678033 · validated civic_curation pubmed
Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma.
· Mol Cancer Res · 2014 · PMID 24962318 · validated civic_curation pubmed

Showing 151–175 of 185 publications

← Previous
1
…
6
7
8
Next →

BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells.

· Oncotarget · 2015 · PMID 26397223 · validated civic_curation pubmed

The effect of flavopiridol on the growth of p16+ and p16- melanoma cell lines.

· Melanoma Res · 2003 · PMID 12777976 · validated civic_curation pubmed

Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.

· PLoS One · 2011 · PMID 22194965 · validated civic_curation pubmed

Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes.

· Oncotarget · 2015 · PMID 26304929 · validated civic_curation pubmed

Pathological activation of KIT in metastatic tumors of acral and mucosal melanomas.

· Int J Cancer · 2009 · PMID 19035443 · validated civic_curation pubmed

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.

· Cell · 2016 · PMID 27667683 · validated civic_curation pubmed

Amuvatinib has cytotoxic effects against NRAS-mutant melanoma but not BRAF-mutant melanoma.

· Melanoma Res · 2014 · PMID 24950457 · validated civic_curation pubmed

Crizotinib, a c-Met inhibitor, prevents metastasis in a metastatic uveal melanoma model.

· Mol Cancer Ther · 2013 · PMID 24140933 · validated civic_curation pubmed

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.

· Cell · 2010 · PMID 20141835 · validated civic_curation pubmed

Primary and Metastatic Melanoma With NTRK Fusions.

· Am J Surg Pathol · 2018 · PMID 29683819 · validated civic_curation pubmed

Shain et al. Nat Genet 2015

· 2015 · PMID 26343386 · validated cbioportal_study pubmed

Liu et al. Nature Medicine 2019

· 2019 · PMID 31792460 · validated cbioportal_study pubmed

Gide et al. Cancer Cell 2019

· 2019 · PMID 30753825 · validated cbioportal_study pubmed

Hugo et al. Cell 2016

· 2016 · PMID 26997480 · validated cbioportal_study pubmed

Riaz et al. Cell 2017

· 2017 · PMID 29033130 · validated cbioportal_study pubmed

Alexander N et al. Clin Cancer Res 2021

· 2021 · PMID 33509808 · validated cbioportal_study pubmed

Liang et al. Genome Res 2017

· 2017 · PMID 28373299 · validated cbioportal_study pubmed

Hodis et al. Cell 2012

· 2012 · PMID 22817889 · validated cbioportal_study pubmed