Publication
Pathological activation of KIT in metastatic tumors of acral and mucosal melanomas.
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Int J Cancer2009PMID 19035443stubpubmedProvenance
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- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
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- ING-CIVIC-20260908-000001
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Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
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- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 19035443
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| KIT D820Y1 | ||||||||
| Sunitinib | Melanoma | Predictive | D | Supports Sensitivity Response | 2 | accepted | EID288828 acral or mucosal melanomas were examined for KIT expression and mutations (exons 11, 13, 17, and 18). Two of 19 melanomas examined harbored KIT mutations, with one subject harboring a D820Y mutatio… (full text at CIViC) PMID 19035443 · Ashida et al., 2009 · Open in CIViC | civic |