Hematologic Malignancy
Mantle Cell Lymphoma
CI-CAN-00005962MCLExplore in graph →
Hematologic180 active trials5 approved drugs7 evidence items
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Hematologic Malignancy
CI-CAN-00005962MCLExplore in graph →
Genomics
1 cohort mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
29 cases with simple somatic mutation data · 29 cases total · 2026-01-08 · mapped to Mantle Cell Lymphoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | ATM | Ssm | 12 | 29 | 41.4% | cbioportal |
| 2 | CCND1 | Ssm | 10 | 29 | 34.5% | cbioportal |
| 3 | TP53 | Ssm | 6 | 29 | 20.7% | cbioportal |
| 4 | KMT2D | Ssm | 4 | 29 | 13.8% | cbioportal |
| 5 | NSD2 | Ssm | 4 | 29 | 13.8% | cbioportal |
| 9 | CRYBG3 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 10 | CSMD2 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 7 | BIRC3 |
Data updated 21 days agoSource updated 2026-01-08
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 2 |
| 29 |
| 6.9% |
| cbioportal |
| 11 | DCP1B | Ssm | 2 | 29 | 6.9% | cbioportal |
| 15 | KIAA1671 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 16 | LUZP4 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 17 | MEF2B | Ssm | 2 | 29 | 6.9% | cbioportal |
| 18 | PCSK2 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 19 | RGS4 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 20 | SLC17A6 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 21 | SP140 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 22 | SYNE1 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 23 | TAS2R41 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 24 | TLR2 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 25 | TNRC6B | Ssm | 2 | 29 | 6.9% | cbioportal |
| 26 | TRPM6 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 27 | TTN | Ssm | 2 | 29 | 6.9% | cbioportal |
| 28 | UBR5 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 14 | FLNC | Ssm | 2 | 29 | 6.9% | cbioportal |
| 29 | UNC80 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 13 | DNAJC6 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 8 | CHMP4C | Ssm | 2 | 29 | 6.9% | cbioportal |
| 12 | DLGAP2 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 6 | ABCC9 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 59 | ARID5A | Ssm | 1 | 29 | 3.4% | cbioportal |