Cancer
Malignant Uterine Corpus Neoplasm
CI-CAN-00008020Explore in graph →
Top-level411 active trials4 approved drugs28 evidence items
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Cancer
CI-CAN-00008020Explore in graph →
Genomics
20 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
95 cases with simple somatic mutation data · 81 cases total · 2026-01-13 · mapped to Endometrial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | PTEN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 75 |
| 95 |
| 78.9% |
| cbioportal |
| 2 | PIK3CA | Ssm | 47 | 95 | 49.5% | cbioportal |
| 3 | ARID1A | Ssm | 43 | 95 | 45.3% | cbioportal |
| 4 | PIK3R1 | Ssm | 36 | 95 | 37.9% | cbioportal |
| 5 | KRAS | Ssm | 31 | 95 | 32.6% | cbioportal |
| 6 | CTNNB1 | Ssm | 29 | 95 | 30.5% | cbioportal |
| 7 | CTCF | Ssm | 27 | 95 | 28.4% | cbioportal |
| 8 | KMT2B | Ssm | 23 | 95 | 24.2% | cbioportal |
| 10 | ZFHX3 | Ssm | 21 | 95 | 22.1% | cbioportal |
| 9 | TP53 | Ssm | 21 | 95 | 22.1% | cbioportal |
| 13 | ZFHX4 | Ssm | 19 | 95 | 20% | cbioportal |
| 11 | DOCK3 | Ssm | 19 | 95 | 20% | cbioportal |
| 12 | INPPL1 | Ssm | 19 | 95 | 20% | cbioportal |
| 15 | MUC16 | Ssm | 18 | 95 | 18.9% | cbioportal |
| 14 | FBXW7 | Ssm | 18 | 95 | 18.9% | cbioportal |
| 17 | KMT2D | Ssm | 17 | 95 | 17.9% | cbioportal |
| 16 | HERC2 | Ssm | 17 | 95 | 17.9% | cbioportal |
| 22 | RBM27 | Ssm | 16 | 95 | 16.8% | cbioportal |
| 18 | JAK1 | Ssm | 16 | 95 | 16.8% | cbioportal |
| 19 | LRTM3 | Ssm | 16 | 95 | 16.8% | cbioportal |
| 21 | PCLO | Ssm | 16 | 95 | 16.8% | cbioportal |
| 20 | NSD1 | Ssm | 16 | 95 | 16.8% | cbioportal |
| 25 | SYNE1 | Ssm | 16 | 95 | 16.8% | cbioportal |
| 24 | SCAF4 | Ssm | 16 | 95 | 16.8% | cbioportal |
| 23 | RPL22 | Ssm | 16 | 95 | 16.8% | cbioportal |
| 27 | DNAH17 | Ssm | 15 | 95 | 15.8% | cbioportal |
| 31 | ZNF469 | Ssm | 15 | 95 | 15.8% | cbioportal |
| 30 | OBSCN | Ssm | 15 | 95 | 15.8% | cbioportal |
| 29 | LMAN1 | Ssm | 15 | 95 | 15.8% | cbioportal |
| 28 | HUWE1 | Ssm | 15 | 95 | 15.8% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13