Subtype
Malignant Neoplasm of Unknown Primary
CI-CAN-00001150CUPExplore in graph →
4,158 active trials54 approved drugs532 evidence items
- NCIt
- C8566
- Other
- 1 more code
Loading cancer entity…
Subtype
CI-CAN-00001150CUPExplore in graph →
Clinical trials
14,253 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (1,895)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05724875 | FLASH Radiotherapy for Skin Cancer(LANCE) | active not recruiting | N/A | 60 | Centre Hospitalier Universitaire VaudoisOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT06008977 | Exercise to Boost Response to Checkpoint Blockade Immunotherapy(EX-BOOST) | active not recruiting | N/A | 12 | AdventHealth Translational Research InstituteOTHER | 1 | Mar 25, 2026 |
| clinicaltrials |
| NCT07493070 | Ultra-stable Iodized Oil-Chemo Embolization Seq Thermal Ablation in Early Liver Ca | active not recruiting | N/A | 30 | Fujian Medical University Union HospitalOTHER | 1 | Mar 25, 2026 | clinicaltrials |
| NCT04804371 | Dual Tracer (68Ga-DOTATATE and 18F-FDG) PET Imaging in G2 & G3 Gastroenteropancreatic Neuroendocrine Tumors | active not recruiting | N/A | 40 | University Health Network, TorontoOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT05318274 | Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer. | active not recruiting | N/A | 72 | Coordinación de Investigación en Salud, MexicoOTHER_GOV | 1 | Mar 23, 2026 | clinicaltrials |
| NCT00185744 | Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer | active not recruiting | N/A | 121 | Stanford UniversityOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT07484776 | Metabolic Flexibility in Patients With Early Triple-negative Breast Cancer | active not recruiting | N/A | 40 | Universidad Europea de MadridOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT06712797 | Physical Activity and Nutrition to Halt Elevated Risk in the Pancreas Interception Center(PANTHER-PIC) | active not recruiting | N/A | 24 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT01928589 | Partial Irradiation and Sequential vs. Concurrent Chemo Early Breast Cancer | active not recruiting | N/A | 81 | Richard ZellarsOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT04395469 | FAZA PET/MRI Pancreas | active not recruiting | N/A | 20 | University Health Network, TorontoOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT05953337 | Radioembolization Trial Utilizing Eye90 Microspheres™ for the Treatment of Hepatocellular Carcinoma (HCC) | active not recruiting | N/A | 120 | ABK BiomedicalINDUSTRY | 2 | Mar 4, 2026 | clinicaltrials |
| NCT01345851 | Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery | active not recruiting | N/A | 29 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT02296229 | Stereotactic Body Radiation Therapy in Treating Patients With Localized High-Risk Prostate Cancer | active not recruiting | N/A | 220 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT04258813 | Onco-primary Care Networking to Support TEAM-based Care(ONE TEAM) | active not recruiting | N/A | 313 | Duke UniversityOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT07407205 | Tumor Mutational Burden, Liquid Biopsy, Angiogenic Factors and DCE-MRI Perfusion in HPV-Negative Oropharyngeal Cancer | active not recruiting | N/A | 30 | Institute of Oncology LjubljanaOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT02226276 | Copper Cu 64-DOTA-Trastuzumab PET in Predicting Response to Treatment With Ado-Trastuzumab Emtansine in Patients With Metastatic HER2 Positive Breast Cancer | active not recruiting | N/A | 10 | City of Hope Medical CenterOTHER | 1 | Feb 13, 2026 | clinicaltrials |
| NCT04736121 | Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients(DOORwaY90) | active not recruiting | N/A | 100 | Sirtex MedicalINDUSTRY | 1 | Feb 3, 2026 | clinicaltrials |
| NCT01918683 | TACE With or Without SBRT as Bridging Therapy for Pre-transplant HCC Patients | active not recruiting | N/A | 40 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Jan 29, 2026 | clinicaltrials |
| NCT02492607 | Management of Low-risk (Grade I and II) DCIS(LORD) | active not recruiting | N/A | 2,500 | The Netherlands Cancer InstituteOTHER | 1 | Jan 26, 2026 | clinicaltrials |
| NCT03878342 | Radiotherapy Omission in Low Risk Ductal in Situ Carcinoma Breast(ROMANCE) | active not recruiting | N/A | 295 | UNICANCEROTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT05338905 | Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial | active not recruiting | N/A | 72 | Roswell Park Cancer InstituteOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT05708599 | A Study to Compare Tissue and Liquid Biopsies in People With Different Types of Cancer | active not recruiting | N/A | 102 | Boehringer IngelheimINDUSTRY | 1 | Jan 21, 2026 | clinicaltrials |
| NCT05735912 | EUS-RFA Versus Surgery for Pancreatic Insulinoma (ERASIN-RCT)(ERASIN-RCT) | active not recruiting | N/A | 60 | Azienda Ospedaliera Universitaria Integrata VeronaOTHER | 1 | Jan 13, 2026 | clinicaltrials |
| NCT04573881 | The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER EU/UK)(#HOPE4LIVER) | active not recruiting | N/A | 24 | HistoSonics, Inc.INDUSTRY | 4 | Jan 12, 2026 | clinicaltrials |
| NCT02399124 | Post Marketing Surveillance for PROSENSE™ a Cryotherapy Treatment of Renal Cell Carcinoma(ICE-SECRET) | active not recruiting | N/A | 120 | IceCure Medical Ltd.INDUSTRY | 1 | Jan 6, 2026 | clinicaltrials |
| NCT06418126 | Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer(TNBC-RT2023) | active not recruiting | N/A | 15 | Centre Paul StraussOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT05934929 | Contribution of Residual Tumour DNA Testing on the Surgical Bed(MARGINS) | active not recruiting | N/A | 31 | Centre Henri BecquerelOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT04124198 | Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma(QoLATI) | active not recruiting | N/A | 138 | Christian von BuchwaldOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT04537312 | Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM) | active not recruiting | N/A | 4 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Dec 22, 2025 | clinicaltrials |
| NCT02352883 | MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ | active not recruiting | N/A | 368 | ECOG-ACRIN Cancer Research GroupNETWORK | 1 | Dec 19, 2025 | clinicaltrials |
| NCT04002479 | Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic Cancer | active not recruiting | N/A | 37 | Alpha Tau Medical LTD.INDUSTRY | 1 | Dec 2, 2025 | clinicaltrials |
| NCT02921022 | Study Of Gemcitabine, Nab-paclitaxel, PEGPH20 and Rivaroxaban for Advanced Pancreatic Adenocarcinoma | active not recruiting | N/A | 110 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT06132087 | PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy | active not recruiting | N/A | 2 | University of Southern CaliforniaOTHER | 1 | Nov 25, 2025 | clinicaltrials |
| NCT04572633 | The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy(#HOPE4LIVER US) | active not recruiting | N/A | 47 | HistoSonics, Inc.INDUSTRY | 1 | Nov 19, 2025 | clinicaltrials |
| NCT04902352 | The DISSECT Study: Effect of Peri-aDventItial SMA diSsECtion on Margin sTatus During Pancreaticoduodenectomy for Resectable Pancreatic Cancer | active not recruiting | N/A | 102 | University Hospital Birmingham NHS Foundation TrustOTHER | 1 | Nov 18, 2025 | clinicaltrials |
| NCT01796145 | Fibroscan Study in HCC | active not recruiting | N/A | 207 | Chinese University of Hong KongOTHER | 1 | Nov 17, 2025 | clinicaltrials |
| NCT02735252 | PROMOTE: Identifying Predictive Markers of Response for Genitourinary Cancer | active not recruiting | N/A | 156 | University of California, San FranciscoOTHER | 1 | Nov 12, 2025 | clinicaltrials |
| NCT04986670 | NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer | active not recruiting | N/A | 299 | Tufts UniversityOTHER | 1 | Sep 30, 2025 | clinicaltrials |
| NCT06728358 | The Future Management of Patients With Neoplasms of the Gastro-intestinal Tract(SOCRATE) | active not recruiting | N/A | 300 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT03216421 | Intraoperative Radiation Therapy (IORT) in DCIS | active not recruiting | N/A | 265 | Columbia UniversityOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT05027477 | A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer(CAPTAIN) | active not recruiting | N/A | 201 | Profound Medical Inc.OTHER | 3 | Aug 17, 2025 | clinicaltrials |
| NCT02984410 | Study Assessing The "Best of" Radiotherapy vs the "Best of" Surgery in Patients With Oropharyngeal Carcinoma(Best Of) | active not recruiting | N/A | 112 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 8 | Aug 14, 2025 | clinicaltrials |
| NCT06248528 | Comparing the Prognosis of Patients With HCC and PVTT Treated With Surgery Versus Locoregional Therapy. | active not recruiting | N/A | 1,076 | Chen XiaopingOTHER | 1 | Jul 16, 2025 | clinicaltrials |
| NCT02041845 | Two Schedules of Hyperfractionated Thoracic Radiotherapy in Limited Disease Small Cell Lung Cancer(THORA) | active not recruiting | N/A | 177 | Norwegian University of Science and TechnologyOTHER | 3 | Jun 6, 2025 | clinicaltrials |
| NCT07002788 | Comparison Paravertebral and Serratus Anterior Plane Block in Video-assisted Thoracoscopic Surgery. | active not recruiting | N/A | 122 | Hacettepe UniversityOTHER | 1 | Jun 4, 2025 | clinicaltrials |
| NCT06312826 | Abbreviated MRI Using Gadoxetic Acid Versus Ultrasonography for Surveillance of Early-stage HCC in Patients at High Risk | active not recruiting | N/A | 806 | Asan Medical CenterOTHER | 1 | May 31, 2025 | clinicaltrials |
| NCT04791735 | Value of the Laparoscopic Approach in the Surgical Management of Resectable Hepatocellular Carcinoma(LapCHC) | active not recruiting | N/A | 252 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | May 28, 2025 | clinicaltrials |
| NCT05657249 | Alternative Surveillance Program for Patients With High Risk Group of HCC | active not recruiting | N/A | 199 | Seoul National University HospitalOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT03460067 | Omission of Radiation in Patients With Her-2 Positive Breast Cancer | active not recruiting | N/A | 12 | University of Kansas Medical CenterOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT05612477 | Blood Salvage in Orthotopic Liver Transplantation With HCC(SOLT) | active not recruiting | N/A | 30 | University Health Network, TorontoOTHER | 1 | Mar 17, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Mar 27, 2026source: clinicaltrials