Clinical trial · Interventional
Contribution of Residual Tumour DNA Testing on the Surgical Bed
Contribution of Residual Tumour DNA Testing on the Surgical Bed of Squamous Cell Carcinomas of the Oral Cavity
NCT05934929CI-TRIAL-00100029MARGINSactive not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to evaluate the interest of residual tumour DNA research in the operating bed after squamous cell carcinoma excision.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Squamous Cell Carcinoma of the Oral Cavity | Oral Cavity Squamous Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Circulating tumor DNA detection | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- circulating tumor DNA detection on operating bed
- description
- biological assessment on operating bed to detect residual circulating tumor DNA
- interventionNames
- Other: Circulating tumor DNA detection
Primary outcomes (1)
- measure
- Residual tumro DNA on operating bed
- timeFrame
- during the surgery
- description
- Proportion of patients with residual tumour DNA on the operating bed according to the presence or absence of adverse histological factors
Secondary outcomes (1)
- measure
- Survival without locoregional recurrence rate
- timeFrame
- 24 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Signed informed consent * Patient with T1 to T4 squamous cell carcinoma of the oral cavity, regardless of lymph node status (all N) M0, operable * 18 years of age or older * Member or beneficiary of a social security scheme. Exclusion Criteria: * Absence of signed informed consent * Patient of protected age * Psychosocial problems * Not affiliated to or benefiting from a social security scheme * Previous cervical irradiation * Pregnant or breast-feeding women * Patient unable to understand the study for any reason or to comply with the constraints of the trial (language, psychological, geographical problems, etc.).
References
Publications (0)
Data not yet available
No reference posted for this study.