Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04165031 | A Study of LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation | terminated | Phase 1 / Phase 2 | 5 | Eli Lilly and CompanyINDUSTRY | 2 | Nov 24, 2021 | clinicaltrials |
| NCT01324141 | Topical MTS-01 for Dermatitis During Radiation and Chemotherapy for Anal Cancer | terminated | Phase 1 | 6 | National Cancer Institute (NCI)NIH | 1 | Nov 23, 2021 | clinicaltrials |
| NCT02319304 |
| Pelvic Radiotherapy With Concurrent Neoadjuvant FOLFOX for Patients With Newly Diagnosed Rectal Adenocarcinoma(GCC 1314) |
| terminated |
| Phase 2 |
| 3 |
| University of Maryland, BaltimoreOTHER |
| 1 |
| Nov 4, 2021 |
| clinicaltrials |
| NCT01505166 | Randomized Phase II Adjuvant Chemotherapy ± FANG™ in Colorectal Carcinoma With Liver Metastases(FANG-CLM) | terminated | Phase 2 | 3 | Gradalis, Inc.INDUSTRY | 1 | Nov 1, 2021 | clinicaltrials |
| NCT02173990 | Aflibercept and Chemotherapy as First Line Treatment for Metastatic Colorectal Cancer Assessable With DCE-US (PULSAR).(PULSAR) | terminated | Phase 2 | 40 | Centre Oscar LambretOTHER | 1 | Oct 20, 2021 | clinicaltrials |
| NCT03699410 | Observational Study on Rectal Cancer to Verify if Response After Chemo-radiotherapy Can be Predicted With a Particular Blood Test.(LiBReCa) | terminated | — | 25 | Dimitri ChristoforidisOTHER | 1 | Oct 13, 2021 | clinicaltrials |
| NCT03176264 | PDR001 in Combination With Bevacizumab and mFOLFOX6 as First Line Therapy in Patients With Metastatic MSS Colorectal Cancer | terminated | Phase 1 | 1 | Novartis PharmaceuticalsINDUSTRY | 1 | Oct 12, 2021 | clinicaltrials |
| NCT02163785 | Abdominoperineal Extra-Elevators Rectal Resection for Cancer: Prone Position vs. Supine Position(APPRO) | terminated | N/A | 280 | Hospital Universitario La FeOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT04158349 | Intraperitoneal Oxaliplatin in Combo w IV mFOLFIRI for Peritoneal Carcinomatosis From Colorectal & Appendiceal Cancer(IPOX-FOLFIRI) | terminated | Phase 1 | 1 | University of UtahOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT03280277 | Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer | terminated | Early Phase 1 | 2 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 10, 2021 | clinicaltrials |
| NCT02851004 | Special Combination of BBI608 and Pembrolizumab | terminated | Phase 1 / Phase 2 | 55 | Takayuki YoshinoOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT02908451 | A Study of AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary Cancer | terminated | Phase 1 | 39 | AbGenomics B.V Taiwan BranchINDUSTRY | 2 | Jul 13, 2021 | clinicaltrials |
| NCT01767857 | A Phase III Study of Xilonix in Patients With Advanced Colorectal Cancer(XCITE) | terminated | Phase 3 | 643 | Janssen Research & Development, LLCINDUSTRY | 13 | Jun 29, 2021 | clinicaltrials |
| NCT03856255 | Polyp Measurement Device | terminated | N/A | 36 | NYU Langone HealthOTHER | 1 | Jun 14, 2021 | clinicaltrials |
| NCT03311750 | Anti-EGFR Therapy Rechallenge in Combination With Chemotherapy in Patients With Advanced Colorectal Cancer(A-REPEAT) | terminated | Phase 2 | 23 | Hellenic Cooperative Oncology GroupOTHER | 2 | Jun 7, 2021 | clinicaltrials |
| NCT02448810 | Phase 2a Study of BAX69 and 5-FU/Leucovorin or Panitumumab Versus Standard of Care in Subjects With Metastatic Colorectal Cancer | terminated | Phase 2 | 115 | Baxalta now part of ShireINDUSTRY | 1 | May 25, 2021 | clinicaltrials |
| NCT03158610 | Biological-guided Metronomic Chemotherapy as Maintenance Strategy in Metastatic Colorectal Cancer | terminated | Phase 2 / Phase 3 | 20 | Ruijin HospitalOTHER | 1 | May 3, 2021 | clinicaltrials |
| NCT02117466 | Image Guided Treatment Optimization With Cetuximab for Patients With Metastatic Colorectal Cancer(IMPACT-CRC) | terminated | Phase 1 / Phase 2 | 85 | Amsterdam UMC, location VUmcOTHER | 1 | Apr 14, 2021 | clinicaltrials |
| NCT03137706 | Characterization of Mechanical Tissue Properties in Patients With Pancreatic, Liver, or Colon Cancer | terminated | — | 8 | University of Southern CaliforniaOTHER | 1 | Apr 5, 2021 | clinicaltrials |
| NCT01280643 | Combination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal Cancer | terminated | N/A | 3 | Fox Chase Cancer CenterOTHER | 1 | Mar 15, 2021 | clinicaltrials |
| NCT02550743 | BrUOG 302:BYL719, Capecitabine and Radiation for Rectal Cancer: A Brown University Oncology Research Group Study | terminated | Phase 1 | 7 | howard safranOTHER | 1 | Mar 12, 2021 | clinicaltrials |
| NCT00005944 | Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer | terminated | Phase 2 | — | UNICANCEROTHER | 2 | Feb 17, 2021 | clinicaltrials |
| NCT01318161 | Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery(EPICOL) | terminated | Phase 3 | 221 | Örebro University, SwedenOTHER | 1 | Feb 16, 2021 | clinicaltrials |
| NCT02614157 | Lateral Lymph Node Dissection After Neoadjuvant Chemo-radiation in Advanced Low Rectal Cancer | terminated | N/A | 51 | West China HospitalOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT04664543 | Efficacy of Free Versus Low Residue Diet as Preparation for Screening Colonoscopy(CriLi) | terminated | N/A | 100 | Parc Taulí Hospital UniversitariOTHER | 1 | Jan 26, 2021 | clinicaltrials |
| NCT03149679 | The p53 Colorectal Cancer Trial | terminated | Phase 2 | 12 | Haukeland University HospitalOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT03170115 | Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer(ICAR) | terminated | Phase 2 | 25 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Dec 17, 2020 | clinicaltrials |
| NCT00023868 | Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655) | terminated | Phase 3 | — | American College of Radiology Imaging NetworkNETWORK | 1 | Dec 2, 2020 | clinicaltrials |
| NCT00986440 | Study of CS-7017 in Colorectal Cancer Patients Who Have Achieved Disease Control Following First-Line Chemotherapy | terminated | Phase 2 | 84 | Daiichi SankyoINDUSTRY | 9 | Nov 5, 2020 | clinicaltrials |
| NCT02010567 | Neoadjuvant Chemoradiotherapy With CRLX-101 and Capecitabine for Rectal Cancer | terminated | Phase 1 / Phase 2 | 32 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Nov 3, 2020 | clinicaltrials |
| NCT02757391 | CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors | terminated | Phase 1 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 30, 2020 | clinicaltrials |
| NCT03724253 | [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)(NeoFIND) | terminated | Phase 2 | 19 | Advanced Accelerator ApplicationsINDUSTRY | 2 | Oct 23, 2020 | clinicaltrials |
| NCT00671645 | Preoperative Combined RadioChemo-Molecular Target Therapy With Capecitabine, Bevacizumab, and Radiotherapy | terminated | Phase 2 | 8 | Austrian Breast & Colorectal Cancer Study GroupNETWORK | 1 | Oct 19, 2020 | clinicaltrials |
| NCT02012231 | Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers. | terminated | Phase 1 | 5 | Fore BiotherapeuticsINDUSTRY | 1 | Oct 19, 2020 | clinicaltrials |
| NCT03549338 | Sym004 Versus Futuximab or Modotuximab in Patients With mCRC | terminated | Phase 2 | 2 | Symphogen A/SINDUSTRY | 4 | Sep 28, 2020 | clinicaltrials |
| NCT03957096 | A Safety Study of SGN-CD47M in Patients With Solid Tumors | terminated | Phase 1 | 16 | Seagen Inc.INDUSTRY | 1 | Sep 17, 2020 | clinicaltrials |
| NCT03029988 | An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases. | terminated | Phase 1 | 3 | Navidea BiopharmaceuticalsINDUSTRY | 1 | Sep 10, 2020 | clinicaltrials |
| NCT01367275 | Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGF | terminated | Phase 2 | 8 | M.D. Anderson Cancer CenterOTHER | 1 | Sep 3, 2020 | clinicaltrials |
| NCT02346955 | Study of CM-24 (MK-6018) Alone and In Combination With Pembrolizumab (MK-3475) in Participants With Selected Advanced or Recurrent Malignancies (MK-6018-001) | terminated | Phase 1 | 27 | Famewave Ltd.INDUSTRY | 2 | Aug 27, 2020 | clinicaltrials |
| NCT03035253 | A Study of OMP-305B83 in Subjects With Metastatic Colorectal Cancer | terminated | Phase 1 | 16 | OncoMed Pharmaceuticals, Inc.INDUSTRY | 1 | Aug 11, 2020 | clinicaltrials |
| NCT01249443 | Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection | terminated | Phase 1 | 17 | AIDS Malignancy ConsortiumNETWORK | 1 | Jul 29, 2020 | clinicaltrials |
| NCT00740961 | Older Patients With Newly Diagnosed Breast Cancer or Colon Cancer | terminated | — | 63 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 27, 2020 | clinicaltrials |
| NCT02453490 | Compare Efficacy and Safety of Raltitrexed-based and 5fu-based Neoadjuvant Chemotherapy for Colorectal Liver Metastasis | terminated | Phase 3 | 360 | Zhejiang UniversityOTHER | 1 | Jul 14, 2020 | clinicaltrials |
| NCT02652702 | Study Comparing Circular Stapler-assisted Colostomy vs Hand-stitching Colostomy of Colorectal Cancer Patients(STAPLER) | terminated | Phase 2 | 60 | Zhejiang UniversityOTHER | 1 | Jul 7, 2020 | clinicaltrials |
| NCT00568425 | QOL & Functional Outcomes After Combined Modality Tx for Anal CA: Comparison of Conventional vs IMRT | terminated | — | 10 | Stanford UniversityOTHER | 1 | Jun 29, 2020 | clinicaltrials |
| NCT02205307 | A Study Assessing Perfusion Outcomes With PINPOINT® Near Infrared Fluorescence Imaging in Low Anterior Resection(PILLAR III) | terminated | N/A | 347 | Novadaq Technologies ULC, now a part of StrykerINDUSTRY | 1 | Jun 24, 2020 | clinicaltrials |
| NCT03300609 | 5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab | terminated | Phase 3 | 4 | University of Southern CaliforniaOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT03480152 | Messenger RNA (mRNA)-Based, Personalized Cancer Vaccine Against Neoantigens Expressed by the Autologous Cancer | terminated | Phase 1 / Phase 2 | 5 | National Cancer Institute (NCI)NIH | 1 | Jun 2, 2020 | clinicaltrials |
| NCT03258541 | Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy | terminated | N/A | 2 | Thomas ZilliOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT02052921 | Observation Versus Surgical Resection in Patients With Rectal Cancer Who Achieved Complete Clinical Response After Neoadjuvant Chemoradiotherapy | terminated | N/A | 13 | Instituto do Cancer do Estado de São PauloOTHER | 1 | May 11, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Nov 24, 2021source: clinicaltrials