Clinical trial · Observational
Characterization of Mechanical Tissue Properties in Patients With Pancreatic, Liver, or Colon Cancer
Characterization of Mechanical Tissue Properties in Pancreas, Liver and Colon
NCT03137706CI-TRIAL-00051057terminatedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Insufficient accrual
Summary
Brief summary (as posted)
This pilot research trial studies characterization of mechanical tissue properties in patients with pancreatic, liver, or colon cancer. Mechanical properties and stiffness of the cancerous tissue may be correlated with the standard pathology report that describes the stage of the disease.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Carcinoma | Colon Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Liver and Intrahepatic Bile Duct Carcinoma | Liver Carcinoma | ALIAS | 0.90 |
| Pancreatic Carcinoma | Pancreatic Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biospecimen Collection | Procedure | — | UNRESOLVED |
| Laboratory Biomarker Analysis | Other | — | UNRESOLVED |
| Laboratory Procedure | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Ancillary-correlative (tissue stiffness analysis)
- description
- Patients undergo fresh tumor tissue collection at the time of surgery. The fresh tumor tissue samples are analyzed for tissue stiffness measurements using optical polarimeter device and cell viability using automated cell counter.
- interventionNames
- Procedure: Biospecimen Collection
- Other: Laboratory Biomarker Analysis
- Other: Laboratory Procedure
Primary outcomes (1)
- measure
- Young's modulus (stiffness) on fresh tissue
- timeFrame
- Up to 15 months
- description
- A portable optical fiber polarimetric sensor device to measure the Young's modulus in tissue samples will be used.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Scheduled for surgery to remove primary tumors in the pancreas, liver or colon and have not undergone any prior treatment * Ability to understand and the willingness to sign a written informed consent Exclusion Criteria: * Pregnant women will not be consented * Patients that are unable to consent for surgery * Primary liver tumors with cirrhosis will be excluded from this study
References
Publications (0)
Data not yet available
No reference posted for this study.