Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,500 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07651020 | The Clinical Application Value of SPECT Imaging Targeting LRRC15 in Malignant Tumors | completed | — | 1 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jun 16, 2026 | clinicaltrials |
| NCT01596790 | COLOSPOT Study : Assessment by EPISPOT of Circulating Tumor Cells in Patients With Metastatic Colorectal Cancer | completed | N/A | 168 | University Hospital, MontpellierOTHER | 1 |
| Jun 12, 2026 |
| clinicaltrials |
| NCT02697084 | Individual Following in Anal Cancer With PET/CT(IFACT) | completed | — | 110 | Centre Antoine LacassagneOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT06035731 | Evaluation of the Medical Service by Socio-aesthetics in Oncology(RCT-SE) | completed | N/A | 400 | Centre Hospitalier de ValenceOTHER | 1 | Jun 11, 2026 | clinicaltrials |
| NCT03289962 | A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors | completed | Phase 1 | 273 | Genentech, Inc.INDUSTRY | 8 | Jun 8, 2026 | clinicaltrials |
| NCT06420726 | Resistance Exercise and Creatine in Colorectal Cancer | completed | N/A | 27 | University of South CarolinaOTHER | 1 | Jun 5, 2026 | clinicaltrials |
| NCT05520866 | PrehabPal: A Digital Tool to Help Older Adults Prepare for Cancer Surgery | completed | N/A | 132 | University of California, San FranciscoOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT05546476 | Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15(PROACC-1) | completed | Phase 2 | 187 | PfizerINDUSTRY | 11 | Jun 3, 2026 | clinicaltrials |
| NCT06192862 | Effectiveness of Using Mobile Health Technology in Colorectal Cancer Screening Uptake | completed | N/A | 500 | Chinese University of Hong KongOTHER | 1 | Jun 3, 2026 | clinicaltrials |
| NCT07527832 | An Observational Study to Learn About the Medicine - BEVACIZUMAB BS [Pfizer] in Colorectal Cancer Patients From Japan. | completed | — | 1,000 | PfizerINDUSTRY | 1 | Jun 3, 2026 | clinicaltrials |
| NCT07619768 | Self Regulation Hypnotic Intervention for Pain and Anxiety During Rectal Brachytherapy | completed | N/A | 52 | Sir Mortimer B. Davis - Jewish General HospitalOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT00002968 | Edrecolomab in Treating Patients With Stage II Colon Cancer | completed | Phase 3 | 2,100 | National Cancer Institute (NCI)NIH | 1 | Jun 1, 2026 | clinicaltrials |
| NCT00159484 | Phase I/II Study of Celebrex and EPO906 in Patients With Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 75 | University of Southern CaliforniaOTHER | 1 | May 28, 2026 | clinicaltrials |
| NCT06876961 | Effect of Arm Cycling Exercise on Pulmonary Functions After Colectomy In Elderly | completed | N/A | 60 | Cairo UniversityOTHER | 1 | May 28, 2026 | clinicaltrials |
| NCT00600496 | A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886) | completed | Phase 1 | 140 | AstraZenecaINDUSTRY | 1 | May 27, 2026 | clinicaltrials |
| NCT04753359 | Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer(Bridge CRC) | completed | N/A | 180 | University of Illinois at ChicagoOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT05084833 | ASPIRES (Activating Cancer Survivors and Their Primary Care Providers to Increase Colorectal Cancer Screening) Study(ASPIRES) | completed | N/A | 300 | Ann & Robert H Lurie Children's Hospital of ChicagoOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT06884839 | Tumor Deposits in Colorectal Cancer and Its Prognostic Value in Survival and Metastasis | completed | — | 30 | Minia UniversityOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT05064059 | A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007) | completed | Phase 3 | 441 | Merck Sharp & Dohme LLCINDUSTRY | 21 | May 26, 2026 | clinicaltrials |
| NCT07585344 | Interrupted 'Figure-of-X' Versus Continuous Suturing Technique for Abdominal Wall Closure in Colorectal Laparotomies(X-CLOSURE) | completed | N/A | 40 | Islamabad Medical and Dental CollegeOTHER | 1 | May 26, 2026 | clinicaltrials |
| NCT02350530 | FOLFOXIRI With or Without Bevacizumab as First-line Treatment for Unresectable Liver-only Metastatic Colorectal Cancer Patients With RAS Mutation-type(FORBES) | completed | Phase 2 | 138 | Sun Yat-sen UniversityOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT03095781 | Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer | completed | Phase 1 | 47 | Emory UniversityOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT06540807 | SafeHeal Anastomosis Feasibility Evaluation (SAFE)-2023 Study | completed | N/A | 24 | SafeHeal IncINDUSTRY | 1 | May 20, 2026 | clinicaltrials |
| NCT01150045 | Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery | completed | Phase 3 | 2,527 | Alliance for Clinical Trials in OncologyOTHER | 3 | May 19, 2026 | clinicaltrials |
| NCT07597330 | POD Risk for Colorectal Cancer Surgery | completed | — | 590 | LanZhou UniversityOTHER | 1 | May 19, 2026 | clinicaltrials |
| NCT07597759 | Phase IIT Trial of SNA009 | completed | Early Phase 1 | 12 | SmartNuclide BiopharmaINDUSTRY | 1 | May 19, 2026 | clinicaltrials |
| NCT07592338 | Agreement Between Large Language Model-Generated Treatment Recommendations With Guideline-Based and Tumor Board Decisions in Gastrointestinal Cancer(KITuKo) | completed | — | 30 | Medizinische Hochschule Brandenburg Theodor FontaneOTHER | 1 | May 18, 2026 | clinicaltrials |
| NCT04406714 | Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)(SCORE) | completed | N/A | 4,318 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | May 15, 2026 | clinicaltrials |
| NCT04776837 | Predicting Disease Progression and/or Recurrence in Cancer | completed | — | 159 | Massachusetts General HospitalOTHER | 1 | May 15, 2026 | clinicaltrials |
| NCT06255041 | Detection of Cancer in Breath Samples by Trained Detection Dogs | completed | — | 1,386 | SpotitEarlyINDUSTRY | 1 | May 15, 2026 | clinicaltrials |
| NCT02514278 | Optimisation of Response for Organ Preservation in Rectal Cancer : Neoadjuvant Chemotherapy and Radiochemotherapy vs. Radiochemotherapy(GRECCAR12) | completed | Phase 3 | 218 | University Hospital, BordeauxOTHER | 1 | May 14, 2026 | clinicaltrials |
| NCT03086096 | CIRSE Registry for LifePearl Microspheres(CIREL) | completed | — | 152 | Cardiovascular and Interventional Radiological Society of EuropeOTHER | 1 | May 13, 2026 | clinicaltrials |
| NCT03017807 | Safety and Pharmacokinetics of Recombinant Anti-EGFr Antibody in Patients With Metastatic Colorectal Cancer | completed | Phase 1 | 18 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.INDUSTRY | 1 | May 12, 2026 | clinicaltrials |
| NCT06173375 | Head to Head Pilot Trial of Mailed Cologuard to Mailed FIT | completed | N/A | 12 | University of California, San DiegoOTHER | 1 | May 12, 2026 | clinicaltrials |
| NCT07200388 | How Emotional Granularity Helps Build Resilience in Young and Middle-Aged Colorectal Cancer Survivors | completed | — | 242 | The Hong Kong Polytechnic UniversityOTHER | 1 | May 12, 2026 | clinicaltrials |
| NCT00959647 | A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study | completed | Phase 2 | 19 | Genentech, Inc.INDUSTRY | 1 | May 8, 2026 | clinicaltrials |
| NCT04835142 | Comparison of A140 and Erbitux Combined With mfolfox6 to Evaluate Efficacy and Safety of First-line Treatment for Ras Wild-type mCRC | completed | Phase 3 | 688 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.INDUSTRY | 1 | May 8, 2026 | clinicaltrials |
| NCT04864067 | No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer(NOAHS-ARC) | completed | Phase 2 | 39 | Servicio de Salud Metropolitano Sur OrienteOTHER_GOV | 1 | May 8, 2026 | clinicaltrials |
| NCT03552718 | QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers. | completed | Phase 1 | 5 | NantBioScience, Inc.INDUSTRY | 1 | May 7, 2026 | clinicaltrials |
| NCT06189846 | Lumeneye Rectoscope for Assessment on Tumor Response After Total Neoadjuvant Treatment in Rectal Cancer(LUMEVAL) | completed | — | 82 | Bordeaux Colorectal Institute AcademyOTHER | 5 | May 7, 2026 | clinicaltrials |
| NCT04130854 | INNATE: Immunotherapy During Neoadjuvant Therapy for Rectal Cancer | completed | Phase 2 | 58 | University of Texas Southwestern Medical CenterOTHER | 1 | May 6, 2026 | clinicaltrials |
| NCT04726319 | Family History App in Personalized Medicine(FHAMe) | completed | N/A | 627 | University of TorontoOTHER | 1 | May 6, 2026 | clinicaltrials |
| NCT03336658 | Intratumoral Budding (ITB) in Preoperative Biopsies of Colon and Rectal Cancer(ITB) | completed | — | 150 | Insel Gruppe AG, University Hospital BernOTHER | 1 | May 5, 2026 | clinicaltrials |
| NCT03797326 | Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005) | completed | Phase 2 | 611 | Merck Sharp & Dohme LLCINDUSTRY | 17 | May 4, 2026 | clinicaltrials |
| NCT06152276 | SafeHeal Diverting Ileostomy Pivotal Study(SH-SOC23) | completed | — | 132 | SafeHeal IncINDUSTRY | 4 | May 4, 2026 | clinicaltrials |
| NCT02837263 | PI Pembro in Combination With Stereotactic Body Radiotherapy for Liver Metastatic Colorectal Cancer | completed | Phase 1 | 15 | University of Wisconsin, MadisonOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT05180565 | Safe Anastomosis Feasibility Study(SAFE2019) | completed | N/A | 27 | SafeHeal IncINDUSTRY | 2 | May 1, 2026 | clinicaltrials |
| NCT05004350 | A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.(NAUTICALCRC) | completed | Phase 2 | 107 | Pierre Fabre MedicamentINDUSTRY | 1 | Apr 30, 2026 | clinicaltrials |
| NCT06212128 | RAPIDO vs LCRT vs Upfront Surgery - a Prospective Cohort Study(RAPIDO) | completed | — | 57 | Sengkang General HospitalOTHER | 0 | Apr 30, 2026 | clinicaltrials |
Data updated 22 days agoSource updated Jun 16, 2026source: clinicaltrials