Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06633133 | Virtual Ileostomy Versus Diverting Ileostomy in Patients Undergoing Total Mesorectal Excision | recruiting | N/A | 620 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Oct 16, 2024 | clinicaltrials |
| NCT05250648 | Clinical Trial on HIPEC With Mitomycin C in Colon Cancer Peritoneal Metastases (GECOP-MMC)(GECOP-MMC) | recruiting | Phase 4 | 216 | Hospital Universitario de FuenlabradaOTHER |
| 1 |
| Oct 9, 2024 |
| clinicaltrials |
| NCT05955196 | Test of CD47-SIRPα Inhibitors on the Immune Microenvironment Colon Cancer(MACROSWITCH) | recruiting | — | 115 | Institut Paoli-CalmettesOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT06184698 | Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer | recruiting | Phase 2 | 173 | Hebei Medical University Fourth HospitalOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT06632886 | AI-Assisted Non-Contrast CT for Multi-Cancer Screening | recruiting | N/A | 1,000,000 | Guo ShiWeiOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT06220045 | Comparing PP and PVDF Meshes in Midline Laparotomy Closure for High-risk Colorectal Surgery. Impact on Incisional Hernia and Surgical Wound Infection.(PROFIMESH) | recruiting | N/A | 60 | Institut d'Investigació Biomèdica de Girona Dr. Josep TruetaOTHER | 1 | Oct 8, 2024 | clinicaltrials |
| NCT06220058 | Comparing Polypropylene Mesh and "Small Bites" Technique in Emergency Colorectal Surgery's Midline Laparotomy Closure. Study for Incisional Hernia Prevention.(BITEME) | recruiting | N/A | 148 | Fernandez ZamoraOTHER | 1 | Oct 8, 2024 | clinicaltrials |
| NCT06452745 | Early Diagnosis of Colorectal Cancer Based on a Non-invasive Metabolomics Profile(EarlyCRC) | recruiting | — | 2,000 | Institut Investigacio Sanitaria Pere VirgiliOTHER | 1 | Oct 2, 2024 | clinicaltrials |
| NCT05628038 | The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer(TORCH-R) | recruiting | Phase 2 | 93 | Fudan UniversityOTHER | 1 | Oct 1, 2024 | clinicaltrials |
| NCT06613581 | Patient-led Follow-up from Home After Surgery for Colorectal Carcinoma(PROMISE) | recruiting | N/A | 200 | Erasmus Medical CenterOTHER | 1 | Sep 26, 2024 | clinicaltrials |
| NCT06259552 | A Study of SPX-303, a Bispecific Antibody Targeting LILRB2 and PD-L1 in Patients With Solid Tumors(SPX-303) | recruiting | Phase 1 | 232 | SparX Biotech(Jiangsu) Co., Ltd.OTHER | 1 | Sep 24, 2024 | clinicaltrials |
| NCT06609551 | ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study(ZJCH-CRCC-1) | recruiting | Phase 3 | 312 | Zhejiang Cancer HospitalOTHER | 1 | Sep 24, 2024 | clinicaltrials |
| NCT05961969 | Robotic Top-down Intersphincteric Resection | recruiting | — | 40 | National Taiwan University HospitalOTHER | 1 | Sep 20, 2024 | clinicaltrials |
| NCT05964530 | Radical vs Local Excision for Rectal Cancer With Clinically Complete Remission | recruiting | N/A | 180 | National Taiwan University HospitalOTHER | 1 | Sep 20, 2024 | clinicaltrials |
| NCT05970133 | Robotic Versus Laparoscopy NOSE for Stage I-III Left-sided Colon Cancer | recruiting | N/A | 300 | National Taiwan University HospitalOTHER | 1 | Sep 20, 2024 | clinicaltrials |
| NCT02919644 | Vaccination with Autologous Dendritic Cells Loaded with Autologous Tumour Homogenate After Curative Resection for Stage IV Colorectal Cancer.(COREVAX-1) | recruiting | Phase 2 | 19 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT03779009 | Minimally INvasive Colon Cancer Surgery Through IMmunomics and Optical Mapping of the Sentinel Lymph Node.(MINIMAL) | recruiting | N/A | 70 | University Hospital, GhentOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT05168839 | Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage(FLUOCOL-1) | recruiting | Phase 3 | 1,010 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06493760 | A Phase 2 Study of SSGJ-707 in Metastatic Colorectal Cancer Patients | recruiting | Phase 2 | 130 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.INDUSTRY | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06589388 | ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer | recruiting | — | 100 | Gene SolutionsINDUSTRY | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06603376 | Irinotecan Hydrochloride Liposome Injection (Ⅱ) Combined with Fluorouracil, Folinic Acid, Vermofenib and Cetuximab in First-line Treatment of BRAFV600E Mutated Advanced Colorectal Cancer | recruiting | Phase 2 | 75 | Shanghai Changzheng HospitalOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT04498767 | Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)(OligoRARE) | recruiting | N/A | 200 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 7 | Aug 26, 2024 | clinicaltrials |
| NCT06185556 | COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases(COLDFIRE-III) | recruiting | Phase 2 / Phase 3 | 78 | Amsterdam UMC, location VUmcOTHER | 1 | Aug 23, 2024 | clinicaltrials |
| NCT06566755 | Cadonilimab (AK104) Combined With Chemotherapy and Bevacizumab as First-line Treatment for RAS Mutated or Right Sided-metastatic MSS Colorectal Cancer | recruiting | Phase 3 | 30 | Caigang LiuOTHER | 1 | Aug 22, 2024 | clinicaltrials |
| NCT06563986 | FTD-TPI, Bevacizumab, and Radioembolization With 166Ho-microspheres in Refractory Metastatic Colorectal Cancer(STARLIGHT) | recruiting | Phase 2 | 40 | UMC UtrechtOTHER | 1 | Aug 21, 2024 | clinicaltrials |
| NCT05215535 | Liver Magnetic Resonance Imaging Before Treatment for Rectal Cancer. A Randomised Controlled Trial.(Limerick) | recruiting | N/A | 400 | Vastra Gotaland RegionOTHER_GOV | 1 | Aug 19, 2024 | clinicaltrials |
| NCT04680260 | OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer(OPTIMISE) | recruiting | Phase 2 | 350 | Karen-Lise Garm SpindlerOTHER | 1 | Aug 14, 2024 | clinicaltrials |
| NCT05572801 | NOAC9 - Circulating Tumor DNA Guided Follow-Up in Anal Cancer | recruiting | N/A | 400 | Aarhus University HospitalOTHER | 4 | Aug 14, 2024 | clinicaltrials |
| NCT06551207 | Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRC | recruiting | N/A | 80 | Liu HuangOTHER | 1 | Aug 13, 2024 | clinicaltrials |
| NCT06341296 | Phase II Study of Irinotecan Liposomes in First-line Treatment of Metastatic Colorectal Cancer | recruiting | Phase 2 | 86 | West China HospitalOTHER | 1 | Aug 12, 2024 | clinicaltrials |
| NCT06544720 | SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas | recruiting | Phase 1 | 18 | The Affiliated Hospital of Qingdao UniversityOTHER | 1 | Aug 9, 2024 | clinicaltrials |
| NCT05939687 | Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection(ProMeLAR) | recruiting | Phase 3 | 142 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Aug 7, 2024 | clinicaltrials |
| NCT06534762 | Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study | recruiting | Phase 2 | 260 | Zhejiang Provincial People's HospitalOTHER | 1 | Aug 2, 2024 | clinicaltrials |
| NCT06536127 | Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScore® in Patients With Non Metastatic Rectal Cancer(IMMUNOREC) | recruiting | N/A | 100 | Institut Sainte CatherineOTHER | 1 | Aug 2, 2024 | clinicaltrials |
| NCT06524245 | A Predictive Model for Recurrence of Colorectal Cancer Based on Multi-omics of Portal Vein Blood(PVMRD) | recruiting | — | 350 | Peking University Shougang HospitalOTHER | 1 | Jul 31, 2024 | clinicaltrials |
| NCT06509126 | Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer(IMPROVE-2) | recruiting | Phase 3 | 500 | National Cancer Institute, NaplesOTHER | 1 | Jul 19, 2024 | clinicaltrials |
| NCT06243393 | Sacituzumab Govitecan in Metastatic Colorectal Cancer(TROPHIT1) | recruiting | Phase 2 / Phase 3 | 80 | University Hospital HeidelbergOTHER | 1 | Jul 10, 2024 | clinicaltrials |
| NCT05462236 | MNK Inhibitor AUM001 in Combination With Either Pembrolizumab or Irinotecan to Treat Metastatic Colorectal Cancer | recruiting | Phase 2 | 120 | AUM Biosciences Pte LtdOTHER | 1 | Jul 9, 2024 | clinicaltrials |
| NCT06314646 | Transanal Transection and Single-stapled Anastomosis (TTSS) in Rectal Cancer Patients(TTSS-REC) | recruiting | — | 472 | Istituto Clinico HumanitasOTHER | 1 | Jun 27, 2024 | clinicaltrials |
| NCT06385418 | Fluorouracil Treatment Via Colon for Colorectal Cancer | recruiting | Phase 2 | 40 | The Second Hospital of Nanjing Medical UniversityOTHER | 1 | Jun 26, 2024 | clinicaltrials |
| NCT05187338 | Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 100 | Second Affiliated Hospital of Guangzhou Medical UniversityOTHER | 1 | Jun 25, 2024 | clinicaltrials |
| NCT02864485 | Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases | recruiting | N/A | 20 | University Health Network, TorontoOTHER | 1 | Jun 18, 2024 | clinicaltrials |
| NCT04050345 | Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer(TRACC) | recruiting | — | 1,000 | Royal Marsden NHS Foundation TrustOTHER | 1 | Jun 14, 2024 | clinicaltrials |
| NCT06455124 | Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE) | recruiting | Phase 2 | 60 | Fudan UniversityOTHER | 1 | Jun 13, 2024 | clinicaltrials |
| NCT06449937 | Local Liver Treatment for Multi-organ Colorectal Cancer Metastases | recruiting | N/A | 130 | Anhui Provincial HospitalOTHER_GOV | 1 | Jun 10, 2024 | clinicaltrials |
| NCT06446050 | Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer | recruiting | Early Phase 1 | 30 | Shanghai East HospitalOTHER | 1 | Jun 6, 2024 | clinicaltrials |
| NCT03349762 | Huaier Granules for Prevention of Recurrence and Metastasis of Colorectal Cancer Patients Following Radical Surgery | recruiting | — | 3,060 | Xi Shan WangOTHER | 1 | Jun 3, 2024 | clinicaltrials |
| NCT05954078 | Circulating Tumor DNA Methylation Guided Postoperative Adjuvant Chemotherapy for High-risk Stage II/III Colorectal Cancer | recruiting | Phase 3 | 340 | Fudan UniversityOTHER | 1 | May 20, 2024 | clinicaltrials |
| NCT06167967 | Circulating Tumor DNA Methylation Guiding Postoperative Adjuvant Chemotherapy in Stage III Colorectal Cancer(cmPAT) | recruiting | N/A | 990 | Sir Run Run Shaw HospitalOTHER | 1 | May 17, 2024 | clinicaltrials |
| NCT05927584 | Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment(LORENA) | recruiting | — | 145 | Fundación de Investigación Biomédica - Hospital Universitario de La PrincesaOTHER | 1 | May 14, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Oct 16, 2024source: clinicaltrials