Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,500 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02928692 | Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium(MAPOCD) | unknown | Phase 3 | 750 | RenJi HospitalOTHER | 1 | Jan 28, 2020 | clinicaltrials |
| NCT02077868 | Evaluation of MGN1703 Maintenance Treatment in Patients With mCRC With Tumor Reduction During Induction Treatment(IMPALA) | unknown | Phase 3 | 540 | Mologen AGINDUSTRY | 8 | Sep 10, 2019 |
| NCT03522649 | A Phase III Clinical Study of Napabucasin (GB201) Plus FOLFIRI in Adult Patients With Metastatic Colorectal Cancer | unknown | Phase 3 | 668 | 1Globe Health Institute LLCINDUSTRY | 1 | Jun 18, 2019 | clinicaltrials |
| NCT02736942 | COLOR III Trial: Transanal vs Laparoscopic TME(COLORIII) | unknown | Phase 3 | 1,104 | Amsterdam UMC, location VUmcOTHER | 1 | Jun 6, 2019 | clinicaltrials |
| NCT01092481 | Study Investigating the Role of Oxaliplatin Duration in Modified FOLFOX-6 or CAPOX Regimen as Adjuvant Colon Cancer Therapy | unknown | Phase 3 | 1,580 | Samsung Medical CenterOTHER | 1 | May 21, 2019 | clinicaltrials |
| NCT00647530 | Fluorouracil and Oxaliplatin With or Without Panitumumab In Treating Patients With High-Risk Colon Cancer That Can Be Removed by Surgery(FOxTROT) | unknown | Phase 2 / Phase 3 | 1,053 | University of BirminghamOTHER | 1 | May 17, 2019 | clinicaltrials |
| NCT03716063 | Strengthening the Spleen and Reducing Phlegm Method in Improving Radical Resection Rate of Colorectal Cancer | unknown | Phase 3 | 350 | Xiyuan Hospital of China Academy of Chinese Medical SciencesOTHER | 1 | Oct 23, 2018 | clinicaltrials |
| NCT02526836 | Complete Mesocolic Excision With Central Vessel Ligation Compared With Conventional Surgery for Colon Cancer | unknown | Phase 2 / Phase 3 | 40 | Mansoura UniversityOTHER | 2 | Aug 16, 2018 | clinicaltrials |
| NCT03606863 | Peripheral Parenteral Nutrition vs Conventional Fluid in Colorectal Resection in ERAS | unknown | Phase 3 | 200 | Antonio Arroyo SebastianOTHER | 1 | Jul 31, 2018 | clinicaltrials |
| NCT02965248 | Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Versus no HIPEC in Locally Advanced Colorectal Cancer (APEC Study) | unknown | Phase 3 | 147 | Fudan UniversityOTHER | 1 | Jun 19, 2018 | clinicaltrials |
| NCT02907385 | Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing | unknown | Phase 3 | 736 | LifeBond Ltd.INDUSTRY | 7 | Mar 30, 2018 | clinicaltrials |
| NCT01196260 | Combination Chemotherapy Treatments in Patients With Colorectal Cancer Stage II and III | unknown | Phase 2 / Phase 3 | 8,000 | State Key Laboratory of Cancer BiologyNETWORK | 1 | Feb 20, 2018 | clinicaltrials |
| NCT03431428 | Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients | unknown | Phase 3 | 477 | Zhang RuiOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT02369939 | Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy(HYCAN) | unknown | Phase 3 | 118 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 11, 2017 | clinicaltrials |
| NCT01308086 | Adjuvant Therapy(3 vs. 6 Months) With the FOLFOX 4 or XELOX for Stage II or Stage III Colon Cancer | unknown | Phase 3 | 2,000 | Hellenic Oncology Research GroupOTHER | 1 | Aug 9, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT01895257 | Comparing HAI-90Y (SIR-spheres)+Chemotx LV5FU2 Versus Chemotx LV5FU2 Alone to Treat Colorectal Cancer | unknown | Phase 3 | 162 | Universiteit AntwerpenOTHER | 1 | Jul 7, 2017 | clinicaltrials |
| NCT03038217 | Investigation of the Value of ctDNA in Diagnosis, Treatment, and Surveillance of Surgically Resectable Colorectal Cancer | unknown | Phase 3 | 300 | Peking Union Medical College HospitalOTHER | 0 | Feb 3, 2017 | clinicaltrials |
| NCT02978313 | Cetuximab Monotherapy Maintenance Treatment in mCRC | unknown | Phase 2 / Phase 3 | 500 | Ruijin HospitalOTHER | 0 | Nov 30, 2016 | clinicaltrials |
| NCT02935764 | FOLFIRI Versus Irinotecan as Second-line Treatment in Metastatic Colorectal Cancer Patients | unknown | Phase 3 | 164 | Fudan UniversityOTHER | 0 | Oct 17, 2016 | clinicaltrials |
| NCT02912052 | Perioperative Chemotherapy VS Postoperative Chemotherapy for the Treatment of Colon Cancer With Resectable Liver Metastasis(PEPCORLI) | unknown | Phase 3 | 240 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Sep 23, 2016 | clinicaltrials |
| NCT02905968 | Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | unknown | Phase 2 / Phase 3 | 520 | Fudan UniversityOTHER | 1 | Sep 19, 2016 | clinicaltrials |
| NCT02893540 | Metronomic Versus Conventional Chemotherapy in as Maintenance Treatment in mCRC | unknown | Phase 2 / Phase 3 | 250 | Ruijin HospitalOTHER | 1 | Sep 16, 2016 | clinicaltrials |
| NCT02635503 | Safety Study of Totally Laparoscopic Resection With Natural Orifice Specimen Extraction (NOSE) for Rectosigmoid Cancer | unknown | Phase 3 | 366 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Sep 2, 2016 | clinicaltrials |
| NCT02882269 | Neoadjuvant Chemotherapy for the Treatment of Resectable Locally Advanced Colon Cancer | unknown | Phase 2 / Phase 3 | 400 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 0 | Aug 30, 2016 | clinicaltrials |
| NCT01465451 | Intra-operative Chemotherapy With 5-FU for Colorectal Cancer Patients Receiving Curative Resection: Efficacy and Safety(IOCCRC) | unknown | Phase 3 | 695 | Sun Yat-sen UniversityOTHER | 1 | Aug 11, 2016 | clinicaltrials |
| NCT02682589 | Open Versus Laparoscopic Complete Mesocolic Excision for Locally Advanced Colon Cancer(OLCMECC) | unknown | Phase 3 | 1,080 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Jul 6, 2016 | clinicaltrials |
| NCT02796820 | Huaier Granule As Adjuvant Therapy for Colorectal Cancer After Radical Surgery | unknown | Phase 3 | 230 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Jun 15, 2016 | clinicaltrials |
| NCT02785146 | Adjuvant Chemotherapy Combined With Huaier Granule for Treating High-risk Stage II, Stage III Colorectal Cancer | unknown | Phase 3 | 230 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Jun 8, 2016 | clinicaltrials |
| NCT02770911 | Laparoscopic Anterior Resection With or Without "Dog Ear" Double-stapled Anastomosis for Rectal Cancer | unknown | Phase 3 | 250 | Fujian Medical UniversityOTHER | 0 | May 12, 2016 | clinicaltrials |
| NCT02744274 | Efficacy of Acupuncture in Prevention of Chemotherapy Induced Peripheral Neuropathy - a Pilot Study | unknown | Phase 3 | 32 | Tzu-Liang ChenOTHER | 1 | Apr 21, 2016 | clinicaltrials |
| NCT00058474 | Radiation Therapy and Either Capecitabine or Fluorouracil With or Without Oxaliplatin Before Surgery in Treating Patients With Resectable Rectal Cancer | unknown | Phase 3 | 1,608 | NSABP Foundation IncNETWORK | 0 | Mar 23, 2016 | clinicaltrials |
| NCT02607072 | Aspirin for Prevention of Postsurgical Recurrence and Metastasis in Asian Colorectal Cancer Patients: a Multi-center Randomized Trial(APREMEC) | unknown | Phase 3 | 3,000 | The Fourth Affiliated Hospital of Anhui Medical UniversityOTHER | 1 | Nov 18, 2015 | clinicaltrials |
| NCT02350166 | Short-term Effects of LASI Surgery Versus Conventional Laparotomy for Colorectal Liver Metastasis | unknown | Phase 3 | 40 | West China HospitalOTHER | 1 | Nov 17, 2015 | clinicaltrials |
| NCT02024412 | Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in mCRC | unknown | Phase 3 | 240 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Sep 28, 2015 | clinicaltrials |
| NCT02510118 | Synergistic Anti-tumor Effect of ChangTai Keli for Colon Cancer Patients | unknown | Phase 2 / Phase 3 | 360 | Nanjing NingQi Medicine Science and Technology Co., Ltd.INDUSTRY | 1 | Aug 3, 2015 | clinicaltrials |
| NCT02503150 | Trial of Antigen Pulsed Dendritic Cells (APDC) in Metastatic Colorectal Cancer | unknown | Phase 3 | 480 | Second Military Medical UniversityOTHER | 0 | Jul 30, 2015 | clinicaltrials |
| NCT01211210 | Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal Cancer(FOWARC) | unknown | Phase 2 / Phase 3 | 495 | Sun Yat-sen UniversityOTHER | 1 | May 22, 2015 | clinicaltrials |
| NCT01814969 | Preoperative Hyperfractionated Radiotherapy or Radiochemotherapy in Locally Advanced Rectal Cancer. | unknown | Phase 3 | 260 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | May 5, 2015 | clinicaltrials |
| NCT01290783 | Trial of FOLF(HA)Iri Versus FOLFIRI in mCRC(FOLF(HA)iri) | unknown | Phase 3 | 390 | Alchemia OncologyINDUSTRY | 1 | Apr 29, 2015 | clinicaltrials |
| NCT02415699 | DC-CIK Immunotherapy Plus Chemotherapy vs Chemotherapy Alone in the Adjuvant Treatment of Stage III Colorectal Cancer | unknown | Phase 2 / Phase 3 | 100 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Apr 14, 2015 | clinicaltrials |
| NCT02402972 | A Multi-center Randomized Controlled Trial of Intraportal Chemotherapy Combined With Adjuvant Chemotherapy (mFOLFOX6) for Stage II and III Colon Cancer | unknown | Phase 3 | 700 | Xu jianminOTHER | 1 | Mar 31, 2015 | clinicaltrials |
| NCT01423214 | A Trial to Assess Robot-assisted Surgery and Laparoscopy-assisted Surgery in Patients With Mid or Low Rectal Cancer(COLRAR) | unknown | Phase 3 | 540 | Kyungpook National University HospitalOTHER | 1 | Mar 11, 2015 | clinicaltrials |
| NCT02280278 | Cytokine-induced Killer Cell Immunotherapy for Surgical Resected Stage III Colorectal Cancer Patients After Chemotherapy | unknown | Phase 3 | 550 | Sun Yat-sen UniversityOTHER | 1 | Nov 5, 2014 | clinicaltrials |
| NCT01941979 | A Study Comparing Adjuvant Chemotherapy Versus Observation for Patients With Rectal Adenocarcinoma After Neoadjuvant Chemo-Radiotherapy Treatment. | unknown | Phase 3 | 309 | Instituto do Cancer do Estado de São PauloOTHER | 1 | Oct 30, 2014 | clinicaltrials |
| NCT02248038 | A Multicenter Clinical Trial on Laparoscopic Colorectal Cancer Surgery Compared With Open Surgery | unknown | Phase 3 | 1,300 | Cai KailinOTHER | 1 | Sep 25, 2014 | clinicaltrials |
| NCT02125409 | Acetylsalicylic Acid and Colorectal Cancer Prevention: Exploring the Platelet Function of Its Mechanism of Action | unknown | Phase 3 | 40 | Aragon Institute of Health SciencesOTHER | 1 | May 5, 2014 | clinicaltrials |
| NCT00433927 | 5-FU, Folinic Acid and Irinotecan (FOLFIRI) Plus Cetuximab Versus FOLFIRI Plus Bevacizumab in First Line Treatment Colorectal Cancer (CRC) | unknown | Phase 3 | 568 | PD Dr. med. Volker HeinemannOTHER | 1 | Mar 14, 2014 | clinicaltrials |
| NCT01426490 | The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | unknown | Phase 2 / Phase 3 | 300 | Taichung Veterans General HospitalOTHER | 1 | Feb 19, 2014 | clinicaltrials |
| NCT00008281 | Comparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer | unknown | Phase 3 | — | SanofiINDUSTRY | 2 | Jan 6, 2014 | clinicaltrials |
Data updated 22 days agoSource updated Jan 28, 2020source: clinicaltrials