Complete Mesocolic Excision With Central Vessel Ligation Compared With Conventional Surgery for Colon Cancer

Inclusion Criteria:

* Pathologically proven adenocarcinoma (including mucinous and signet-ring cell) or adenosquamous carcinoma on endoscopic biopsy.
* Tumor localization at the caecum, ascending colon, transverse colon, descending colon, sigmoid colon or rectosigmoid on preoperative endoscopy and radiographic imaging \[barium enema or computed tomography (CT)\] without location of the lower border of the tumor at the rectum.
* No history of familial adenomatous polyposis, ulcerative colitis or Crohn's disease.
* Body mass index ≤ 35.
* Sufficient organ function including cardiovascular system and liver.
* Written informed consent.

Exclusion Criteria:

* Contraindications to major surgery and American Society of Anesthesiologists (ASA) Physical Status scoring 4 which means extreme systemic disorders which have already become an eminent threat to life regardless of the type of treatment.
* Infectious disease requiring treatment.
* Body temperature ≥ 38 °C.
* Pregnant women.
* History of psychiatric disease.
* Use of systemic steroids.
* History of myocardial infarction or unstable angina pectoris within 6 months.
* Severe pulmonary emphysema or pulmonary fibrosis