Subtype
Malignant Intracranial Neoplasm
CI-CAN-00003169Explore in graph →
192 active trials28 evidence items
- NCIt
- C5114
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Subtype
CI-CAN-00003169Explore in graph →
Clinical trials
637 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (100)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00179803 | Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors | completed | Phase 2 | 24 | Ann & Robert H Lurie Children's Hospital of ChicagoOTHER | 1 | Aug 5, 2020 | clinicaltrials |
| NCT00342004 | A Prospective Cohort Study of Occupational Exposures and Cancer Risk Among Women | completed | — | 75,366 | National Cancer Institute (NCI)NIH | 1 | Aug 4, 2020 | clinicaltrials |
| NCT00342953 | Study of Health Effects of Cosmetic Breast Augmentation | completed | — | 17,424 | National Cancer Institute (NCI)NIH | 1 | Jul 14, 2020 | clinicaltrials |
| NCT02502708 | Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors | completed | Phase 1 | 81 | NewLink Genetics CorporationINDUSTRY | 1 | Jun 4, 2020 | clinicaltrials |
| NCT01331135 | Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors(Aflac ST0901) | completed | Phase 1 | 18 | Emory UniversityOTHER | 1 | May 29, 2020 | clinicaltrials |
| NCT02911155 | Cancer and Other Disease Risks in U.S. Nuclear Medicine Technologists | completed | — | 229 | National Cancer Institute (NCI)NIH | 1 | May 5, 2020 | clinicaltrials |
| NCT02743481 | Early Life Exposures in Agriculture | completed | — | 60,000 | National Cancer Institute (NCI)NIH | 1 | Apr 20, 2020 | clinicaltrials |
| NCT01614132 | Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults(NOA-07) | completed | Phase 1 / Phase 2 | 33 | University of RegensburgOTHER | 1 | Mar 31, 2020 | clinicaltrials |
| NCT01067469 | Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM) | completed | Phase 2 | 83 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT00525590 | Exploratory Study, Evaluating the Treatment Effect of Surgery Plus GLIADEL® Wafer in Patients With Metastatic Brain Cancer | completed | Phase 2 | 69 | Eisai Inc.INDUSTRY | 1 | Mar 16, 2020 | clinicaltrials |
| NCT00994071 | A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors | completed | Phase 1 | 9 | National Cancer Institute (NCI)NIH | 1 | Dec 9, 2019 | clinicaltrials |
| NCT01392209 | Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma | completed | Phase 1 | 15 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 22, 2019 | clinicaltrials |
| NCT01654497 | Dexanabinol in Patients With Brain Cancer | completed | Phase 1 | 26 | Santosh Kesari, M.D., Ph.D.OTHER | 1 | Nov 14, 2019 | clinicaltrials |
| NCT02045368 | Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R | completed | Phase 1 | 92 | IGF Oncology, LLCINDUSTRY | 1 | Aug 22, 2019 | clinicaltrials |
| NCT01454596 | CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII | completed | Phase 1 / Phase 2 | 18 | National Cancer Institute (NCI)NIH | 1 | Aug 21, 2019 | clinicaltrials |
| NCT00884741 | Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma | completed | Phase 3 | 637 | National Cancer Institute (NCI)NIH | 3 | Jul 24, 2019 | clinicaltrials |
| NCT02337426 | Dimethyl Fumarate, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | completed | Phase 1 | 12 | Virginia Commonwealth UniversityOTHER | 1 | Jun 28, 2019 | clinicaltrials |
| NCT00001574 | A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors | completed | — | 40 | National Cancer Institute (NCI)NIH | 1 | May 8, 2019 | clinicaltrials |
| NCT00001807 | (1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy | completed | — | 50 | National Cancer Institute (NCI)NIH | 1 | Apr 24, 2019 | clinicaltrials |
| NCT03910556 | Re-craniotomy and Complications After Elective Neurosurgery | completed | — | 439 | Chiang Mai UniversityOTHER | 0 | Apr 12, 2019 | clinicaltrials |
| NCT01688401 | Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG). | completed | Phase 1 | 3 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Mar 28, 2019 | clinicaltrials |
| NCT01644773 | Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG) | completed | Phase 1 | 36 | St. Jude Children's Research HospitalOTHER | 1 | Mar 22, 2019 | clinicaltrials |
| NCT02941536 | Correlation Between Circulating Tumor Cells and Brain Disease Control After Focal Radiotherapy for Metastases of Breast Cancer | completed | N/A | 40 | AC Camargo Cancer CenterOTHER | 1 | Dec 27, 2018 | clinicaltrials |
| NCT01977677 | Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma | completed | Phase 1 / Phase 2 | 30 | Lawrence RechtOTHER | 1 | Oct 23, 2018 | clinicaltrials |
| NCT01151670 | Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors | completed | Phase 1 | 18 | Wake Forest University Health SciencesOTHER | 1 | Aug 1, 2018 | clinicaltrials |
| NCT00749723 | Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children(HIT-REZ-2005) | completed | Phase 2 / Phase 3 | 174 | University Hospital, BonnOTHER | 1 | Jul 20, 2018 | clinicaltrials |
| NCT00805376 | DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas | completed | Phase 1 | 37 | DNAtrix, Inc.INDUSTRY | 1 | Jul 16, 2018 | clinicaltrials |
| NCT00919750 | Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors | completed | — | 1,258 | Children's Oncology GroupNETWORK | 6 | Jul 16, 2018 | clinicaltrials |
| NCT00890786 | A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas | completed | Early Phase 1 | 27 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | May 2, 2018 | clinicaltrials |
| NCT00832598 | [18F] FACBC and [18F] FLT PET Imaging in Central Nervous System Tumors | completed | N/A | 13 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 27, 2018 | clinicaltrials |
| NCT00003456 | Antineoplaston Therapy in Treating Patients With Newly-diagnosed Glioblastoma Multiforme | completed | Phase 2 | 40 | Burzynski Research InstituteOTHER | 1 | Mar 22, 2018 | clinicaltrials |
| NCT00003474 | Antineoplaston Therapy in Treating Adults With Residual/Recurrent/Progressive Glioblastoma Multiforme | completed | Phase 2 | 40 | Burzynski Research InstituteOTHER | 1 | Mar 22, 2018 | clinicaltrials |
| NCT00782756 | Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant Glioma | completed | Phase 2 | 40 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 6, 2018 | clinicaltrials |
| NCT02457715 | Feasibility of a Consumer Based Accelerometer in Monitoring Outpatient Physical Activity: A Study in Patients With Cancer and Amyotrophic Lateral Sclerosis | completed | — | 40 | Duke UniversityOTHER | 1 | Dec 12, 2017 | clinicaltrials |
| NCT01171469 | Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor | completed | Phase 1 | 8 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Dec 2, 2017 | clinicaltrials |
| NCT00381797 | Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma | completed | Phase 2 | 97 | National Cancer Institute (NCI)NIH | 1 | Nov 28, 2017 | clinicaltrials |
| NCT00946673 | Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer | completed | Phase 1 | 17 | Stanford UniversityOTHER | 1 | Oct 6, 2017 | clinicaltrials |
| NCT02452216 | Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS | completed | Early Phase 1 | 10 | Michael IvOTHER | 1 | Aug 31, 2017 | clinicaltrials |
| NCT00003475 | Antineoplaston Therapy in Treating Patients With Primary Malignant Brain Tumors | completed | Phase 2 | 40 | Burzynski Research InstituteOTHER | 1 | Aug 24, 2017 | clinicaltrials |
| NCT01708174 | A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) | completed | Phase 2 | 22 | Novartis PharmaceuticalsINDUSTRY | 13 | Aug 11, 2017 | clinicaltrials |
| NCT01975116 | p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors | completed | Phase 1 | 18 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | Aug 7, 2017 | clinicaltrials |
| NCT00595322 | Bevacizumab in the Radiation Treatment of Recurrent Malignant Glioma | completed | N/A | 25 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 23, 2017 | clinicaltrials |
| NCT00660543 | MRI Study With Ferumoxytol in Assessing Early Response in Patients With Glioblastoma Multiforme Receiving Temozolomide and Radiation Therapy | completed | N/A | 14 | OHSU Knight Cancer InstituteOTHER | 1 | May 16, 2017 | clinicaltrials |
| NCT01393912 | PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma | completed | Phase 1 | 55 | St. Jude Children's Research HospitalOTHER | 1 | Apr 26, 2017 | clinicaltrials |
| NCT00706810 | Combination of Hydroxyurea and Verapamil for Refractory Meningiomas | completed | Phase 2 | 8 | University of UtahOTHER | 1 | Apr 13, 2017 | clinicaltrials |
| NCT01125800 | A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB | completed | Phase 1 / Phase 2 | 76 | Novartis PharmaceuticalsINDUSTRY | 6 | Mar 20, 2017 | clinicaltrials |
| NCT00185848 | Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis | completed | Phase 1 | 10 | Sanjiv Sam GambhirOTHER | 1 | Mar 14, 2017 | clinicaltrials |
| NCT00643097 | Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme(ACTIVATe) | completed | Phase 2 | 40 | John SampsonOTHER | 1 | Feb 1, 2017 | clinicaltrials |
| NCT00723463 | Determine if Apparent Diffusion Coefficient (ADC) Values Can Differentiate Tumors From Normal Tissue | completed | Early Phase 1 | 200 | University of MichiganOTHER | 1 | Nov 2, 2016 | clinicaltrials |
Data updated 23 days agoSource updated Aug 5, 2020source: clinicaltrials