Clinical trial · Observational
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens
NCT00919750CI-TRIAL-00033764completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.
Conditions
Conditions (20)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Atypical Teratoid/Rhabdoid Tumor | ONTOLOGY_EXACT | 0.98 |
| Childhood Central Nervous System Germ Cell Tumor | Childhood Central Nervous System Germ Cell Tumor | ONTOLOGY_EXACT | 0.98 |
| Childhood Cerebral Anaplastic Astrocytoma | Childhood Cerebral Anaplastic Astrocytoma | ONTOLOGY_EXACT | 0.98 |
| Childhood Cerebral Astrocytoma | Childhood Cerebral Astrocytoma | ONTOLOGY_EXACT | 0.98 |
| Childhood Choroid Plexus Neoplasm | Childhood Choroid Plexus Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Childhood Craniopharyngioma | Childhood Craniopharyngioma | ONTOLOGY_EXACT | 0.98 |
| Childhood Grade III Meningioma | Childhood Grade 3 Meningioma | ALIAS | 0.90 |
| Childhood Grade II Meningioma | Childhood Grade 2 Meningioma |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cytology Specimen Collection Procedure | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Ancillary-Correlative (tissue and blood sample collection)
- description
- Brain tumor tissue and blood specimens are collected from patients and banked for future study.
- interventionNames
- Other: Cytology Specimen Collection Procedure
Primary outcomes (3)
- measure
- Collection of brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions
- timeFrame
- Up to 16 years
- measure
- Creation of a repository for long-term storage of these specimens
- timeFrame
- Up to 16 years
- measure
- Making these specimens available to qualified researchers to understand the biology of pediatric brain tumors
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of brain tumor * Previously treated at a Children?s Oncology Group (COG) institution * Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm * Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission
References
Publications (0)
Data not yet available
No reference posted for this study.