Cancer Family
Malignant Head and Neck Neoplasm
CI-CAN-00000236Explore in graph →
1,431 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000236Explore in graph →
Clinical trials
5,448 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (629)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05816785 | Pilot Study of Imatinib Cetuximab Combo for H & N Cancer | completed | Early Phase 1 | 15 | University of Wisconsin, MadisonOTHER | 1 | Sep 4, 2026 | clinicaltrials |
| NCT06366451 | PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC | completed | Early Phase 1 | 17 | Presage BiosciencesINDUSTRY | 1 | Jun 26, 2026 | clinicaltrials |
| NCT04188665 | Using MASL to Combat Oral Cancer | completed | Early Phase 1 | 18 | Rowan UniversityOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT02467738 | Surgical Resection and Intraoperative Cesium-131 Brachytherapy for Head and Neck Cancer | completed | Early Phase 1 | 30 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT05678348 | Pyrimethamine as an Inhibitor of NRF2 in HPV-unrelated Locally Advanced Head and Neck Squamous Cell Carcinoma | completed | Early Phase 1 | 22 | Washington University School of MedicineOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT06273852 | A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors | completed | Early Phase 1 | 8 | Pure Biologics S.A.INDUSTRY | 1 | Aug 11, 2025 | clinicaltrials |
| NCT02145143 | Enhancing Radioiodine (RAI) Incorporation Into BRAF Mutant, RAI-Refractory Thyroid Cancers With the BRAF Inhibitor Vemurafenib: A Pilot Study | completed | Early Phase 1 | 12 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jun 18, 2025 | clinicaltrials |
| NCT03618654 | Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma | completed | Early Phase 1 | 38 | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityOTHER | 1 | May 15, 2025 | clinicaltrials |
| NCT04883645 | Neoadjuvant Imiquimod Immunotherapy for Oral Cancer | completed | Early Phase 1 | 16 | Medical University of South CarolinaOTHER | 1 | Jan 28, 2025 | clinicaltrials |
| NCT03459729 | Pharmacokinetic (PK) Analysis of Antitumor B in Patients With Oral Cancer | completed | Early Phase 1 | 6 | Medical College of WisconsinOTHER | 1 | Jan 16, 2025 | clinicaltrials |
| NCT01821612 | Chemotherapy and Radiation Therapy Before Surgery Followed by Gemcitabine in Treating Patients with Pancreatic Cancer | completed | Early Phase 1 | 23 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jan 13, 2025 | clinicaltrials |
| NCT06413095 | PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STS | completed | Early Phase 1 | 13 | Presage BiosciencesINDUSTRY | 1 | May 14, 2024 | clinicaltrials |
| NCT03868020 | Fluciclovine F18 PET/CT in Identifying the Origin of Head and Neck Squamous Cell Carcinoma in Patients With Metastatic Cervical Nodal Disease | completed | Early Phase 1 | 16 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 28, 2024 | clinicaltrials |
| NCT06062602 | PBI-MST-01(NCT04541108) Substudy TAK-02: Intratumoral Microdosing of TAK-676 in HNSCC | completed | Early Phase 1 | 15 | Presage BiosciencesINDUSTRY | 1 | Oct 6, 2023 | clinicaltrials |
| NCT03575598 | Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study(SNOW) | completed | Early Phase 1 | 10 | University Health Network, TorontoOTHER | 1 | Jul 27, 2023 | clinicaltrials |
| NCT03282461 | A Microdose Evaluation Study of ABY-029 in Head and Neck Oncology Surgery | completed | Early Phase 1 | 12 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | May 18, 2023 | clinicaltrials |
| NCT04065555 | Intratumoral Microdosing of TAK-981 in Head and Neck Cancer | completed | Early Phase 1 | 12 | Presage BiosciencesINDUSTRY | 1 | Jul 29, 2022 | clinicaltrials |
| NCT03647657 | 177Lu-PP-F11N in Combination With Sacubitril for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer | completed | Early Phase 1 | 8 | University Hospital, Basel, SwitzerlandOTHER | 1 | Feb 10, 2022 | clinicaltrials |
| NCT03317730 | Pilot Trial of Microsphere Oxycodone (Xtampza ER) for Pain Management in Patients Receiving Radiotherapy for Locally Advanced Head and Neck Cancer(RAD 1702) | completed | Early Phase 1 | 28 | University of Alabama at BirminghamOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT03182959 | Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer | completed | Early Phase 1 | 6 | University of ArizonaOTHER | 1 | Jun 21, 2021 | clinicaltrials |
| NCT02794675 | Intraoperative Placement of Cesium-131 Permanent Interstitial Brachytherapy in Head and Neck Cancer | completed | Early Phase 1 | 15 | Case Comprehensive Cancer CenterOTHER | 1 | Dec 23, 2020 | clinicaltrials |
| NCT02153450 | Stereotactic Radiosurgery and Metformin in Patients With Borderline-Resectable or Locally-Advanced Pancreatic Cancer | completed | Early Phase 1 | 8 | Case Comprehensive Cancer CenterOTHER | 1 | Jun 26, 2020 | clinicaltrials |
| NCT01359267 | Feasibility of Imaging in the Treatment of Patients With Advanced Head and Neck Cancer | completed | Early Phase 1 | 12 | University of ChicagoOTHER | 1 | May 8, 2020 | clinicaltrials |
| NCT02646319 | Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations | completed | Early Phase 1 | 2 | Mayo ClinicOTHER | 1 | Jun 6, 2019 | clinicaltrials |
| NCT03923998 | Adjuvant ChemoRadiotherapy Prior to Surgery in Stage IVa Oral Cancers | completed | Early Phase 1 | 8 | Indrayani Hospital and Cancer InstituteOTHER | 1 | Apr 23, 2019 | clinicaltrials |
| NCT00601913 | Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery | completed | Early Phase 1 | 24 | Wake Forest University Health SciencesOTHER | 1 | Jul 5, 2018 | clinicaltrials |
| NCT02608736 | Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic Acid(GAMA) | completed | Early Phase 1 | 42 | Barretos Cancer HospitalOTHER | 1 | Feb 1, 2018 | clinicaltrials |
| NCT00395109 | PET/CT to Image Hypoxia in Head and Neck Tumours | completed | Early Phase 1 | 17 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sOTHER | 1 | Aug 28, 2017 | clinicaltrials |
| NCT00723463 | Determine if Apparent Diffusion Coefficient (ADC) Values Can Differentiate Tumors From Normal Tissue | completed | Early Phase 1 | 200 | University of MichiganOTHER | 1 | Nov 2, 2016 | clinicaltrials |
| NCT01160302 | Curcumin Biomarker Trial in Head and Neck Cancer | completed | Early Phase 1 | 33 | Louisiana State University Health Sciences Center ShreveportOTHER | 1 | Mar 2, 2016 | clinicaltrials |
| NCT00696176 | STAT3 DECOY in Head and Neck Cancer | completed | Early Phase 1 | 32 | University of PittsburghOTHER | 1 | Jul 23, 2015 | clinicaltrials |
| NCT01275183 | Pilot Study of Raltegravir and Cisplatin in Squamous Cell Carcinoma of Head and Neck | completed | Early Phase 1 | 5 | New Mexico Cancer Research AllianceOTHER | 1 | Jun 18, 2015 | clinicaltrials |
| NCT00718770 | A Pilot Clinical Trial for Poorly Differentiated Thyroid Cancer - Correlation to Retinoid and Peroxisome-proliferator-activated Receptor (PPARy) Expression | completed | Early Phase 1 | 10 | University of Colorado, DenverOTHER | 1 | Jan 17, 2014 | clinicaltrials |
| NCT00140556 | Angiogenic and EGFR Blockade With Curative Chemoradiation for Advanced Head and Neck Cancer | completed | Early Phase 1 | 28 | David M. Brizel, MDOTHER | 1 | Jan 18, 2013 | clinicaltrials |
| NCT00884520 | An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037(VM4-037) | completed | Early Phase 1 | 16 | Siemens Molecular ImagingINDUSTRY | 1 | Mar 16, 2010 | clinicaltrials |
| NCT00606424 | An Exploratory, Open Label, Single Center Study of [F-18]HX4(HX4) | completed | Early Phase 1 | 10 | Siemens Molecular ImagingINDUSTRY | 1 | Feb 2, 2009 | clinicaltrials |
Data updated 22 days agoSource updated Sep 4, 2026source: clinicaltrials