Clinical trial · Interventional
PET/CT to Image Hypoxia in Head and Neck Tumours
NCT00395109CI-TRIAL-00029288completedEarly Phase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with head and neck cancer will be imaged with PET scan and CT scan in order to determine areas of the tumour that are hypoxic. It is hypothesized that PET /CT will provide information on hypoxia of the tumors and tumor regions in head and neck cancer patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PET/CT | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- FDG/PET visualization of glycolysis/blood flow in tumors and intra-tumor regions;
- timeFrame
- 2 years
- measure
- Measurement of mRNAs levels encoding hypoxia response genes in tumor samples.
- timeFrame
- 2 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * All patients with head and neck tumours (\>3cm diameter) without bone involvement. Exclusion Criteria: * Known allergy to contrast agents * Poor kidney function (serum creatinine level \> 2.0 mg/dL or 177 mmol/L) * Pregnancy * Breast-feeding * Unable to lie supine * Patient who were biopsied or operated upon within the past month. * Patient who were treated with chemotherapy or radiation within the past month. * Tumors that were obscured by artifacts (e.g. tooth fillings) in CT scans.
References
Publications (0)
Data not yet available
No reference posted for this study.