Cancer Family
Malignant Head and Neck Neoplasm
CI-CAN-00000236Explore in graph →
1,431 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000236Explore in graph →
Clinical trials
5,448 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (629)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07694726 | Preventing Lymphedema in Patients Undergoing Surgical Treatment for Head and Neck Cancer Through Vein Reconstruction | not yet recruiting | N/A | 37 | University of PittsburghOTHER | 1 | Aug 19, 2026 | clinicaltrials |
| NCT07772063 | Immunomonitoring of Circulating Immune Cells in Maxillofacial Surgery(IMMUNOFACE) | not yet recruiting | — | 60 | Assistance Publique - Hôpitaux de ParisOTHER | 0 | Aug 19, 2026 |
| clinicaltrials |
| NCT06660017 | Head and Neck Cancer Patients With Oral Mucositis Treated With Ketamine Oral Rinse | not yet recruiting | Phase 2 | 62 | University of OklahomaOTHER | 1 | Aug 18, 2026 | clinicaltrials |
| NCT07766889 | Neoadjuvant Presurgical Becotatug Vedotin (MRG003) Plus Pucotenlimab (HX008) in Oral Cavity Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 32 | Sun Yat-sen UniversityOTHER | 1 | Aug 17, 2026 | clinicaltrials |
| NCT07418034 | A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)(SAVED) | not yet recruiting | Phase 2 | 132 | University of Maryland, BaltimoreOTHER | 0 | Aug 14, 2026 | clinicaltrials |
| NCT07764887 | Impacted Tooth Management and Osteoradionecrosis Risk in NPC | not yet recruiting | N/A | 536 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 1 | Aug 14, 2026 | clinicaltrials |
| NCT07552558 | Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) | not yet recruiting | Phase 1 / Phase 2 | 45 | Washington University School of MedicineOTHER | 1 | Aug 13, 2026 | clinicaltrials |
| NCT07272642 | A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors.(DUNP19) | not yet recruiting | Phase 1 | 16 | Radiopharm Theranostics, LtdINDUSTRY | 1 | Aug 12, 2026 | clinicaltrials |
| NCT07650266 | A Study of Cemiplimab and Fianlimab in People With Nasopharyngeal Carcinoma | not yet recruiting | Phase 1 | 60 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 11, 2026 | clinicaltrials |
| NCT07756684 | Feasibility of Cough Skill Training in Individuals With Head and Neck Cancer | not yet recruiting | N/A | 10 | Boston University Charles River CampusOTHER | 1 | Aug 11, 2026 | clinicaltrials |
| NCT07758621 | SYS6010 vs Investigator's Choice of Monotherapy in Patients With Recurrent or Metastatic HNSCC | not yet recruiting | Phase 3 | 340 | CSPC Megalith Biopharmaceutical Co.,Ltd.INDUSTRY | 0 | Aug 11, 2026 | clinicaltrials |
| NCT07756190 | Radscopal Radiotherapy Plus Immunotherapy for Chemotherapy-Ineligible Patients With Newly Diagnosed Metastatic Nasopharyngeal Cancer: A Single-Center, Open-Label, Phase II Study(RADIANCE) | not yet recruiting | Phase 2 | 28 | Sun Yat-sen UniversityOTHER | 1 | Aug 10, 2026 | clinicaltrials |
| NCT07751276 | Perioperative Finotonlimab Plus Chemotherapy in Untreated Stage II HNSCC | not yet recruiting | Phase 2 | 142 | Yanjie Zhang, MDOTHER | 0 | Aug 7, 2026 | clinicaltrials |
| NCT07751289 | Anti-PD-1 Therapy in Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma(neo-Recur) | not yet recruiting | Phase 2 | 217 | Yanjie Zhang, MDOTHER | 0 | Aug 7, 2026 | clinicaltrials |
| NCT07752875 | A Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation | not yet recruiting | Phase 1 / Phase 2 | 250 | LG ChemINDUSTRY | 0 | Aug 7, 2026 | clinicaltrials |
| NCT07677475 | MRG003 Plus Toripalimab Versus Toripalimab as Neoadjuvant Therapy for PD-L1-Positive, Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 65 | Dongguan People's HospitalOTHER_GOV | 1 | Aug 5, 2026 | clinicaltrials |
| NCT07745803 | Discovery and Validation of Biomarkers for Periodontitis, Dental Caries and Oral Squamous Cell Carcinoma | not yet recruiting | — | 4,000 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityOTHER | 1 | Aug 4, 2026 | clinicaltrials |
| NCT07741565 | Window Trial of Intratumoral (IT) Neoadjuvant Fluorescently Labelled Nivolumab (nivo800) in Head and Neck Squamous Cell Carcinoma (HNSCC) | not yet recruiting | Early Phase 1 | 18 | Vanderbilt-Ingram Cancer CenterOTHER | 0 | Aug 3, 2026 | clinicaltrials |
| NCT07741643 | Study Evaluating the Safety and Feasibility of Panitumumab-IRDye800 and [18F]NOTA-ABY-030 for Targeted Dual-Modality Imaging (TDMI) in Head and Neck Squamous Cell Carcinoma | not yet recruiting | Phase 1 | 30 | Vanderbilt-Ingram Cancer CenterOTHER | 0 | Aug 3, 2026 | clinicaltrials |
| NCT07740616 | Speed of Processing Training to Improve Cognitive Functioning and Driving Performance in Head and Neck Cancer Survivors | not yet recruiting | N/A | 30 | University of Alabama at BirminghamOTHER | 1 | Jul 31, 2026 | clinicaltrials |
| NCT07470489 | Zanzalintinib Plus Cemiplimab for the Treatment of BRAF Wild-Type Anaplastic Thyroid Cancer | not yet recruiting | Phase 2 | 12 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07723495 | Symptom Management to Improve Completion of Patient-reported Outcome Measures | not yet recruiting | N/A | 78 | Henry Ford Health SystemOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07732634 | RiMO-HNC-NEO1: Phase 2 Study of RiMO-301 and Hypofractionated Radiotherapy With Pembrolizumab for the Neoadjuvant Treatment of Resectable, Locally Advanced Head-Neck Cancer(RiMO-HNC-NEO1) | not yet recruiting | Phase 2 | 20 | University of Illinois at ChicagoOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07732686 | Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry | not yet recruiting | — | 2,000 | University of OklahomaOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT04662554 | Study of a 1-Millimeter Resolution Clinical Positron Emission Tomography (PET) System in Head and Neck Cancer Imaging | not yet recruiting | N/A | 10 | Stanford UniversityOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT06411834 | Mapping Patient Decision-making in Thyroid Cancer | not yet recruiting | N/A | 50 | University of California, Los AngelesOTHER | 0 | Jul 24, 2026 | clinicaltrials |
| NCT07606287 | Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital | not yet recruiting | N/A | 4,000 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Jul 23, 2026 | clinicaltrials |
| NCT07168785 | [18F]-AraG PET Imaging in LA HNSCC | not yet recruiting | Early Phase 1 | 5 | Indiana UniversityOTHER | 1 | Jul 22, 2026 | clinicaltrials |
| NCT07241273 | SPECT-CT Guided ELEctive Contralateral Neck Treatment in Lateralized Oropharyngeal Cancer(SELECT-FR) | not yet recruiting | N/A | 128 | UNICANCEROTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT07635381 | A Feasibility Study of AI-Assisted Physiotherapy for Oral Cancer Patients | not yet recruiting | N/A | 15 | National Taiwan University HospitalOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT07714967 | Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients | not yet recruiting | N/A | 100 | Hainan Medical CollegeOTHER | 2 | Jul 20, 2026 | clinicaltrials |
| NCT07064902 | Ivonescimab Combined With Chemoradiotherapy in High-Risk Locoregionally Advanced Nasopharyngeal Carcinoma | not yet recruiting | Phase 2 | 48 | Sun Yat-sen UniversityOTHER | 1 | Jul 16, 2026 | clinicaltrials |
| NCT07521670 | Sacituzumab Tirumotecan in Recurrent/Metastatic Adenoid Cystic Carcinoma and Papillary Thyroid Carcinoma (STRAP)(STRAP) | not yet recruiting | Phase 2 | 68 | National Cancer Centre, SingaporeOTHER | 4 | Jul 15, 2026 | clinicaltrials |
| NCT07662720 | A Phase II Trial for MOR Antagonism With Axelopran to Enhance Immunotherapy in Head and Neck Cancer(MORALE-HN01) | not yet recruiting | Phase 1 / Phase 2 | 18 | Glycyx TherapeuticsINDUSTRY | 0 | Jul 15, 2026 | clinicaltrials |
| NCT07664241 | Peer Support Program for Improving Quality of Life Among Head and Neck Patients, Connecting Through Cancer Trial | not yet recruiting | N/A | 56 | OHSU Knight Cancer InstituteOTHER | 1 | Jul 15, 2026 | clinicaltrials |
| NCT07690631 | Impact of Chronic MICROplastic Exposure on RADiotherapy of Head and Neck Cancer Patients: Clinical and Translational Oncology Study:(MICRORAD) | not yet recruiting | — | 500 | University of KragujevacOTHER | 0 | Jul 15, 2026 | clinicaltrials |
| NCT07705074 | FAPI PET Imaging - An Exploratory Study(FAPIPET) | not yet recruiting | Phase 1 / Phase 2 | 770 | Martin HuellnerOTHER | 1 | Jul 15, 2026 | clinicaltrials |
| NCT07696169 | Disease Evolution and Risk Factors of AIDS-related Prevalent Cancers | not yet recruiting | — | 1,000 | Shenzhen Third People's HospitalOTHER | 0 | Jul 10, 2026 | clinicaltrials |
| NCT07692360 | Salivary IL-6 and Interleukin Gene Polymorphisms in Oral Squamous Cell Carcinoma(IL6-OSCC) | not yet recruiting | — | 38 | University of PaviaOTHER | 1 | Jul 9, 2026 | clinicaltrials |
| NCT07692906 | Multimodal Evaluation-Guided Surveillance-Intervention With Endoscopic Selective Neck Dissection for Post-Radiotherapy N3 Nasopharyngeal Carcinoma | not yet recruiting | N/A | 80 | Xuelei Ma MDOTHER | 0 | Jul 9, 2026 | clinicaltrials |
| NCT07692997 | Sancai Fengsui Decoction for RTOM: A Multicenter RCT | not yet recruiting | Phase 2 | 126 | Nanfang Hospital, Southern Medical UniversityOTHER | 0 | Jul 9, 2026 | clinicaltrials |
| NCT07578467 | Combining Neo-adjuvant ATR-inhibition With Nodal SBRT for Early-stage Resectable HPV+ OPSCCs | not yet recruiting | Phase 1 / Phase 2 | 35 | Abramson Cancer Center at Penn MedicineOTHER | 0 | Jul 8, 2026 | clinicaltrials |
| NCT07578727 | A Multicenter, Prospective, Phase III Clinical Study of Proton Intensity-modulated Radiotherapy Versus Photon Intensity-modulated Radiotherapy for Untreated Non-metastatic Nasopharyngeal Carcinoma | not yet recruiting | N/A | 504 | Guangzhou Concord Cancer CenterOTHER | 1 | Jul 8, 2026 | clinicaltrials |
| NCT07682675 | Study to Evaluate the Efficacy of Zanzalintinib in the Treatment of Relapsed or Metastatic Adenoid Cystic Carcinomas of the Head and Neck(ZANACC) | not yet recruiting | Phase 2 | 51 | UNICANCEROTHER | 1 | Jul 6, 2026 | clinicaltrials |
| NCT07683507 | Becotatug Vedotin Plus PD-1 Inhibitor for Head and Neck Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 60 | Feng LiuOTHER | 0 | Jul 6, 2026 | clinicaltrials |
| NCT07667296 | APG-157 in Locally Advanced Head and Neck Squamous Cell Carcinoma | not yet recruiting | Phase 3 | 826 | Aveta Biomics, Inc.INDUSTRY | 0 | Jul 1, 2026 | clinicaltrials |
| NCT07679997 | Trilaciclib Combined With Immunochemotherapy for R/M HNSCC | not yet recruiting | Phase 2 | 32 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 0 | Jul 1, 2026 | clinicaltrials |
| NCT07674706 | Evaluating the Optimal Timing of Acupuncture for Managing Chemoradiation-induced Xerostomia in Patients With Head and Neck Cancers | not yet recruiting | N/A | 50 | National University Hospital, SingaporeOTHER | 1 | Jun 29, 2026 | clinicaltrials |
| NCT07671573 | Integrated Early-CARE for Head & Neck Cancer.(i-CARE-HN) | not yet recruiting | N/A | 64 | Portuguese Oncology Institute, CoimbraOTHER | 1 | Jun 26, 2026 | clinicaltrials |
| NCT07645846 | Neoadjuvant Docetaxel, Cisplatin, and Dual Immunotherapy for Sinonasal Carcinoma(PANDA) | not yet recruiting | Phase 2 | 23 | Sun Yat-sen UniversityOTHER | 0 | Jun 25, 2026 | clinicaltrials |
Data updated 22 days agoSource updated Aug 19, 2026source: clinicaltrials