Cancer Family
Malignant Head and Neck Neoplasm
CI-CAN-00000236Explore in graph →
1,431 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000236Explore in graph →
Clinical trials
5,448 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (629)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03349710 | Nivolumab or Nivolumab Plus Cisplatin, in Combination With Radiotherapy in Patients With Cisplatin-ineligible or Eligible Locally Advanced Squamous Cell Head and Neck Cancer | completed | Phase 3 | 74 | Bristol-Myers SquibbINDUSTRY | 10 | Aug 9, 2021 | clinicaltrials |
| NCT00293462 | GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer | completed | Phase 3 | 91 | Marilyn DoddOTHER | 1 | Jul 30, 2021 |
| NCT01874587 | Adaptative Radiotherapy to Decrease Xerostomia in Oropharynx Carcinoma(ARTIX) | completed | Phase 3 | 132 | Center Eugene MarquisOTHER | 1 | Jul 27, 2021 | clinicaltrials |
| NCT01427478 | Evaluation of Afatinib in Maintenance Therapy in Squamous Cell Carcinoma of the Head and Neck(BIBW2992ORL) | completed | Phase 3 | 134 | Centre Leon BerardOTHER | 1 | Jun 1, 2021 | clinicaltrials |
| NCT00704730 | Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer(EXAM) | completed | Phase 3 | 330 | ExelixisINDUSTRY | 24 | Apr 20, 2021 | clinicaltrials |
| NCT00003627 | Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Advanced Cancer of the Oropharynx or Hypopharynx | completed | Phase 3 | 160 | UNICANCEROTHER | 1 | Feb 21, 2021 | clinicaltrials |
| NCT02480114 | Gabapentin Compared to Standard of Care in Preventing Mucositis in Patients With Stage III-IV Head and Neck Cancer Undergoing Primary or Adjuvant Chemoradiation Therapy | completed | Phase 3 | 79 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT00004917 | Radiation Therapy With or Without Epoetin Alfa in Treating Anemic Patients With Head and Neck Cancer | completed | Phase 3 | — | Radiation Therapy Oncology GroupNETWORK | 3 | Oct 22, 2020 | clinicaltrials |
| NCT00006481 | Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer | completed | Phase 3 | — | Radiation Therapy Oncology GroupNETWORK | 2 | Oct 22, 2020 | clinicaltrials |
| NCT01969877 | A Study of Cisplatin Plus Radiotherapy Compared to Cetuximab Plus Radiotherapy in Locally Advanced Head and Neck Cancer.(ARTSCANIII) | completed | Phase 3 | 298 | Lund University HospitalOTHER | 1 | Sep 2, 2020 | clinicaltrials |
| NCT00608205 | Radiation Therapy Cisplatin With or Without Fluorouracil Patients With Stage III or Stage IV Head and Neck Cancer | completed | Phase 3 | 69 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 6, 2020 | clinicaltrials |
| NCT00402779 | Erlotinib Prevention of Oral Cancer (EPOC) | completed | Phase 3 | 303 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 21, 2020 | clinicaltrials |
| NCT00158678 | IMRT Plus Cisplatin Versus Conventional Radiotherapy Plus Cisplatin in Stage III-IV HNSCC | completed | Phase 3 | 310 | Groupe Oncologie Radiotherapie Tete et CouOTHER | 1 | Apr 15, 2020 | clinicaltrials |
| NCT00609284 | Randomized Trial of Concomitant Chemotherapy in Patients With Locally Advanced HNSCC Treated by Radiotherapy-erbitux(2007-01) | completed | Phase 3 | 406 | Groupe Oncologie Radiotherapie Tete et CouOTHER | 1 | Apr 15, 2020 | clinicaltrials |
| NCT00004234 | Oral Mucositis in Patients Receiving Radiation Therapy for Cancer of the Mouth, Pharynx, or Larynx | completed | Phase 3 | — | NCIC Clinical Trials GroupNETWORK | 1 | Apr 6, 2020 | clinicaltrials |
| NCT04137627 | Melatonin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response in Locally Advanced Oral Squamous Cell Carcinoma | completed | Phase 3 | 50 | Indonesia UniversityOTHER | 1 | Dec 9, 2019 | clinicaltrials |
| NCT00656513 | Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer | completed | Phase 2 / Phase 3 | 196 | Radiation Therapy Oncology GroupNETWORK | 2 | Nov 19, 2019 | clinicaltrials |
| NCT02715596 | Changes in Body Composition After EPA Supplementation in Head and Neck Patients(hepaneck) | completed | Phase 3 | 54 | Institut Català d'OncologiaOTHER | 1 | Sep 4, 2019 | clinicaltrials |
| NCT00379262 | Therapeutic Gain by Induction-concurrent Chemoradiotherapy and/or Accelerated Fractionation for Nasopharyngeal Carcinoma | completed | Phase 3 | 803 | Hong Kong Nasopharyngeal Cancer Study Group LimitedOTHER | 1 | Aug 7, 2019 | clinicaltrials |
| NCT00442455 | Erlotinib,Radiation and Cisplatin in Patients With Complete Resected Squamous Cell Carcinoma of the Head and Neck | completed | Phase 3 | 53 | Grupo de Investigación Clínica en Oncología RadioterapiaOTHER | 1 | Jun 6, 2019 | clinicaltrials |
| NCT00615420 | A Randomized Placebo-Controlled Trial of Manuka Honey for Oral Mucositis Due to Radiation Therapy for Cancer | completed | Phase 3 | 106 | British Columbia Cancer AgencyOTHER | 1 | Jun 5, 2019 | clinicaltrials |
| NCT00716391 | TPF Plus Cisplatin and Radiotherapy vs TPF Plus Cetuximab and Radiotherapy to Treat Head and Neck Cancer. | completed | Phase 3 | 519 | Grupo Español de Tratamiento de Tumores de Cabeza y CuelloOTHER | 1 | May 24, 2019 | clinicaltrials |
| NCT02586350 | Study of Anlotinib in Patients With Medullary Thyroid Carcinoma(ALTER01031) | completed | Phase 2 / Phase 3 | 91 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | May 21, 2019 | clinicaltrials |
| NCT00002654 | Radiation Therapy With or Without Cisplatin in Treating Patients With Advanced Head and Neck Cancer | completed | Phase 3 | 224 | Swiss Cancer InstituteOTHER | 1 | May 15, 2019 | clinicaltrials |
| NCT02012062 | Concurrent Nimotuzumab Versus Cisplatin With Radiotherapy for Locoregionally Advanced NPC | completed | Phase 3 | 160 | Fudan UniversityOTHER | 1 | Apr 10, 2019 | clinicaltrials |
| NCT02347332 | Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer | completed | Phase 3 | 459 | Pierre Fabre MedicamentINDUSTRY | 1 | Mar 5, 2019 | clinicaltrials |
| NCT00535795 | Phase III: Assess Conventional RT w/ Conventional Plus Accelerated Boost RT in the Treatment of Nasopharyngeal CA | completed | Phase 3 | 200 | King Faisal Specialist Hospital & Research CenterOTHER | 1 | Mar 1, 2019 | clinicaltrials |
| NCT00169182 | Induction CT by Cisplatin, 5FU With or Without Docetaxel in Patients With T3 and T4 Larynx and Hypopharynx Carcinoma | completed | Phase 3 | 220 | Groupe Oncologie Radiotherapie Tete et CouOTHER | 1 | Feb 15, 2019 | clinicaltrials |
| NCT01233843 | Chemoradiotherapy HNSCC, Randomized Study, Docetaxel,Cisplatin, 5FU,Erbitux.(2007/02) | completed | Phase 3 | 370 | Groupe Oncologie Radiotherapie Tete et CouOTHER | 1 | Jan 18, 2019 | clinicaltrials |
| NCT00002839 | Combination Chemotherapy Plus Radiation Therapy To Preserve the Larynx in Patients With Cancer of the Hypopharynx or Larynx | completed | Phase 3 | 564 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 6 | Jul 9, 2018 | clinicaltrials |
| NCT00003888 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer | completed | Phase 3 | 359 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 15 | Jul 9, 2018 | clinicaltrials |
| NCT00117572 | Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE)(DeCIDE) | completed | Phase 3 | 285 | University of ChicagoOTHER | 5 | Apr 9, 2018 | clinicaltrials |
| NCT01434394 | Neoadjuvant Erbitux Based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer(EAGLE) | completed | Phase 2 / Phase 3 | 243 | Shanghai Jiao Tong University School of MedicineOTHER | 1 | Aug 21, 2017 | clinicaltrials |
| NCT01542931 | TPF Induction Chemotherapy for Locally Advanced and Resectable Oral Squamous Cell Carcinoma | completed | Phase 2 / Phase 3 | 256 | Shanghai Jiao Tong University School of MedicineOTHER | 1 | Aug 21, 2017 | clinicaltrials |
| NCT01156142 | Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy | completed | Phase 3 | 155 | Alliance for Clinical Trials in OncologyOTHER | 1 | Aug 9, 2017 | clinicaltrials |
| NCT01917942 | Radiotherapy With Humidification in Head And Neck Cancer(RadioHum) | completed | Phase 3 | 210 | Trans Tasman Radiation Oncology GroupOTHER | 1 | Jul 12, 2017 | clinicaltrials |
| NCT00359645 | Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population | completed | Phase 3 | 1,993 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | May 16, 2017 | clinicaltrials |
| NCT00002727 | Radiation Therapy in Treating Patients With Stage II Cancer of the Vocal Cord | completed | Phase 3 | 250 | Radiation Therapy Oncology GroupNETWORK | 2 | Jan 4, 2017 | clinicaltrials |
| NCT00131638 | A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer | completed | Phase 3 | 241 | AmgenINDUSTRY | 0 | Dec 16, 2016 | clinicaltrials |
| NCT00002533 | Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer | completed | Phase 2 / Phase 3 | — | University of MiamiOTHER | 1 | Dec 15, 2016 | clinicaltrials |
| NCT01083550 | Decision Making on Radioactive Iodine Treatment for Papillary Thyroid Cancer | completed | Phase 2 / Phase 3 | 74 | University Health Network, TorontoOTHER | 1 | Nov 29, 2016 | clinicaltrials |
| NCT00496652 | DAHANCA 19: The Importance of the EGFr-inhibitor Zalutumumab for the Outcome After Curative Radiotherapy for HNSCC | completed | Phase 3 | 619 | Danish Head and Neck Cancer GroupNETWORK | 1 | Nov 25, 2016 | clinicaltrials |
| NCT01540136 | Concurrent Chemoradiotherapy With Nedaplatin Versus Cisplatin in Nasopharyngeal Carcinoma | completed | Phase 3 | 402 | Sun Yat-sen UniversityOTHER | 1 | Oct 28, 2016 | clinicaltrials |
| NCT00101582 | Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer | completed | Phase 3 | 188 | Swedish Orphan BiovitrumINDUSTRY | 0 | Sep 27, 2016 | clinicaltrials |
| NCT00036881 | Zinc Sulfate in Preventing Loss of Sense of Taste in Patients Undergoing Radiation Therapy for Head and Neck Cancer | completed | Phase 3 | 173 | Alliance for Clinical Trials in OncologyOTHER | 0 | Jul 14, 2016 | clinicaltrials |
| NCT00003610 | Capsaicin Lozenges in Treating Patients With Mucositis Caused by Radiation Therapy | completed | Phase 3 | 18 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 13, 2016 | clinicaltrials |
| NCT00174837 | TRACE: Tirapazamine-Radiation And Cisplatin Evaluation(TRACE) | completed | Phase 3 | 317 | SanofiINDUSTRY | 17 | May 26, 2016 | clinicaltrials |
| NCT00795782 | Prophylactic Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma | completed | Phase 3 | 258 | Samsung Medical CenterOTHER | 1 | Apr 15, 2016 | clinicaltrials |
| NCT02303197 | Clinical Trial on the Efficacy and Safety of Chining Decoction in the Treatment of Radiation Stomatitis | completed | Phase 3 | 70 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Dec 22, 2015 | clinicaltrials |
| NCT00003139 | Pilocarpine in Preventing Mucositis and Dry Mouth in Patients Receiving Radiation Therapy for Head and Neck Cancer | completed | Phase 3 | 249 | Radiation Therapy Oncology GroupNETWORK | 2 | Nov 17, 2015 | clinicaltrials |
Data updated 22 days agoSource updated Aug 9, 2021source: clinicaltrials