Cancer Family
Malignant Head and Neck Neoplasm
CI-CAN-00000236Explore in graph →
1,432 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000236Explore in graph →
Clinical trials
5,449 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (629)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03975231 | Dabrafenib, Trametinib, and IMRT in Treating Patients With BRAF Mutated Anaplastic Thyroid Cancer | recruiting | Phase 1 | 6 | City of Hope Medical CenterOTHER | 1 | Apr 8, 2026 | clinicaltrials |
| NCT06444815 | A Study of VET3-TGI in Patients With Solid Tumors(STEALTH-001) | recruiting | Phase 1 | 60 | KaliVir ImmunotherapeuticsINDUSTRY | 1 | Apr 7, 2026 | clinicaltrials |
| NCT06959108 | Clinical Trial Comparing Induction Treatment With EGFR-ADC MRG003 Alone or in Combination With the Anti PD1 Pucotenlimab, Followed by Radiochemotherapy in Locally Advanced Squamous Cell Cancers of the Head and Neck(IDEAL) | recruiting | Phase 2 | 106 | Groupe Oncologie Radiotherapie Tete et CouOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT07514754 | Galenos 2 Immunonutrition in Head and Neck, Lung, and Rectal Cancer Patients(GALENOS 2) | recruiting | N/A | 52 | Fondazione del Piemonte per l'OncologiaOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT05047094 | Alpha Radiation Emitters Device (DaRT) in Combination With Check Point Inhibitor for the Treatment of Recurrent Unresectable or mHNSCC | recruiting | N/A | 48 | Alpha Tau Medical LTD.INDUSTRY | 1 | Apr 6, 2026 | clinicaltrials |
| NCT07511413 | GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients(GALENOS 1) | recruiting | — | 110 | Fondazione del Piemonte per l'OncologiaOTHER | 1 | Apr 6, 2026 | clinicaltrials |
| NCT07512921 | Matching Primary Tumor and Blood Gene Expression Analysis of HPV-negative Squamous Head and Neck Cancers(BIOMATCH) | recruiting | — | 300 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Apr 6, 2026 | clinicaltrials |
| NCT04755855 | Prospective Sinonasal Cancer Multi-institution Study | recruiting | — | 200 | Mayo ClinicOTHER | 1 | Apr 3, 2026 | clinicaltrials |
| NCT05483374 | The Head and Neck Registry of the European Reference Network on Rare Adult Solid Cancers(EURACAN) | recruiting | — | 13,600 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 3 | Apr 3, 2026 | clinicaltrials |
| NCT06785051 | AI-based Physiotherapy for Oral Cancer Patients | recruiting | N/A | 100 | National Taiwan University HospitalOTHER | 1 | Apr 3, 2026 | clinicaltrials |
| NCT04475640 | Cancer Genetic Testing in Ethnic Populations | recruiting | N/A | 1,800 | Mayo ClinicOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT05587543 | Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma | recruiting | Early Phase 1 | 24 | Fudan UniversityOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT06145308 | Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular Typing | recruiting | Phase 2 | 39 | Peking Union Medical CollegeOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT06451497 | This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors | recruiting | Phase 1 | 100 | Zumutor Biologics Inc.INDUSTRY | 1 | Apr 2, 2026 | clinicaltrials |
| NCT07507578 | A Multi-omics Approach to Disclose Progression and Underlying Biology of Head and Neck Adenoid Cystic Carcinoma(MAPPING-ACC) | recruiting | — | 114 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT06137274 | Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC | recruiting | Phase 2 | 35 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Apr 1, 2026 | clinicaltrials |
| NCT06915727 | An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors | recruiting | Phase 3 | 20 | Mayo ClinicOTHER | 1 | Apr 1, 2026 | clinicaltrials |
| NCT07464366 | The Safety and Efficacy of MRG003 With or Without Putrelimab in Recurrent or Metastatic Salivary Gland Cancer: a Single-center, Open-label Cohort Study(TSEMPRMSGC) | recruiting | Phase 2 | 90 | Ji DongmeiOTHER | 1 | Apr 1, 2026 | clinicaltrials |
| NCT07467083 | Development and Application of a Nurse-Led Preemptive Symptom Management Protocol for Head and Neck Cancer Patients Undergoing Radiation Therapy | recruiting | Phase 3 | 170 | West China HospitalOTHER | 1 | Apr 1, 2026 | clinicaltrials |
| NCT06158360 | An Observational Study on Postoperative Symptoms After Thyroidectomy (POS-T) | recruiting | — | 500 | Ilsan Cha hospitalOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT06708754 | Impact of Photobiomodulation (PBM) on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer Patients(PBM-LEF) | recruiting | N/A | 60 | NYU Langone HealthOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT07501650 | Pembrolizumab Plus Ultrasound-Induced Microbubble Cavitation in Head and Neck Cancer | recruiting | Phase 1 | 6 | Thomas Jefferson UniversityOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT06077643 | Workshops and Exchange Groups for Laryngectomized Patients(GELAT) | recruiting | — | 50 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT06207188 | Identification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic Parameters | recruiting | — | 650 | Mayo ClinicOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT07465276 | Neoadjuvant Ficerafusp Alfa With Pembrolizumab in Resectable SCC | recruiting | Phase 2 | 32 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT04185974 | Carbon Ion Re-Radiotherapy in Patients With Recurrent or Progressive Locally Advanced Head-and-Neck Cancer(CARE) | recruiting | N/A | 72 | University Hospital HeidelbergOTHER | 1 | Mar 25, 2026 | clinicaltrials |
| NCT06323460 | Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer | recruiting | Phase 2 | 45 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Mar 24, 2026 | clinicaltrials |
| NCT06344208 | Predicting Toxicity in Elderly Patients With Head and Neck Cancer(PREtoxEL) | recruiting | — | 3 | European Institute of OncologyOTHER | 1 | Mar 24, 2026 | clinicaltrials |
| NCT06146764 | CEUS Improves the Diagnostic Performance of SRSS of Thyroid Carcinoma | recruiting | — | 800 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT06220656 | TRAIL Study: Feasibility and Pilot | recruiting | N/A | 20 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT06554158 | De-escalation of Adjuvant Radiation for Low-Risk HPV Oropharyngeal Cancers | recruiting | N/A | 30 | Georgetown UniversityOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT07125755 | Comparing Postoperative Adjuvant Cisplatin Concurrent Chemoradiotherapy With Adjuvant Radiotherapy Alone for Intermediate-risk Head and Neck Squamous Cell Carcinoma | recruiting | Phase 3 | 386 | Sun Yat-sen UniversityOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT06316895 | The Clinical Outcomes and Prediction of Thermal Ablation for Low-risk Papillary Thyroid Carcinoma | recruiting | — | 3,772 | Chinese PLA General HospitalOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT07485296 | Effect of Postbiotics on Microbiota and Systemic Immunomodulation of Pembrolizumab as First-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (RM HNSCC)(POST-BIO) | recruiting | Phase 2 | 45 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT06184880 | Effect of Physical Activity Program on Sedentary of Patients With Upper Aerodigestive Tract Cancer(APAORL2) | recruiting | N/A | 96 | Centre Hospitalier de ValenceOTHER | 1 | Mar 19, 2026 | clinicaltrials |
| NCT04119024 | Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors | recruiting | Phase 1 | 18 | Anusha KalbasiOTHER | 1 | Mar 17, 2026 | clinicaltrials |
| NCT05539638 | The Role of Circulating Tumour DNA in Head and Neck Cancer | recruiting | — | 250 | University of EdinburghOTHER | 1 | Mar 17, 2026 | clinicaltrials |
| NCT07092514 | Lenvatinib 24 mg/Day Versus 10 mg/Day to Treat Symptomatic or Progressive Radioactive Iodine Resistant (RAIR) Differentiated Thyroid Cancer (DTC) | recruiting | Phase 2 | 34 | Washington University School of MedicineOTHER | 1 | Mar 17, 2026 | clinicaltrials |
| NCT07362979 | Toripalimab Combined With Different Platinum-Based Induction Chemotherapy Regimens for Locally Advanced Nasopharyngeal Carcinoma | recruiting | Phase 2 | 243 | Sun Yat-sen UniversityOTHER | 1 | Mar 17, 2026 | clinicaltrials |
| NCT07459296 | Becotatug Vedotin Plus Sintilimab in Locoregionally Advanced NPC | recruiting | Phase 3 | 266 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT07473518 | Thyroid Carcinoma in Cancer Patients Undergoing Radiotherapy | recruiting | — | 2,550 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT03875716 | Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma | recruiting | N/A | 111 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT06030440 | De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck(DIREKHT2) | recruiting | Phase 2 / Phase 3 | 508 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT06464198 | Prospective Registry Study on the Implementation of Simultaneous Postoperative Radiochemotherapy for Salivary Gland Carcinomas of the Head and Neck Region | recruiting | — | 100 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT06681233 | Feasibility Study of CBCT for IGRT in Cancer Patients | recruiting | N/A | 50 | Varian, a Siemens Healthineers CompanyINDUSTRY | 1 | Mar 13, 2026 | clinicaltrials |
| NCT06211335 | Losartan, Pembrolizumab and Stereotactic Body Radiation Therapy for the Treatment of Patients With Locally Recurrent, Refractory or Oligometastatic Head and Neck Squamous Cell Carcinoma | recruiting | Phase 1 | 24 | University of California, DavisOTHER | 1 | Mar 12, 2026 | clinicaltrials |
| NCT07035249 | DCSZ11 in Combination With Standard Therapy in Advanced or Metastatic Solid Tumors | recruiting | Phase 1 / Phase 2 | 9 | West China HospitalOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT04742608 | Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer | recruiting | — | 250 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT06636188 | An Oncology Nurse AI Agent to Reduce Cancer Distress During Radiotherapy(Digi-Coach) | recruiting | N/A | 138 | The University of Hong KongOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT07412314 | Proton Therapy for Recurrent Nasopharyngeal Carcinoma | recruiting | N/A | 52 | Guangzhou Concord Cancer CenterOTHER | 1 | Mar 9, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Apr 8, 2026source: clinicaltrials