Clinical trial · Observational
Prospective Sinonasal Cancer Multi-institution Study
Sinonasal Cancer Study to Evaluate Oncologic Outcomes and Quality of Life
NCT04755855CI-TRIAL-00107257recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a multi-institution prospective study of patients with sinonasal malignancies. The goal of this study is to learn more about the course of sinonasal cancer, treatment outcomes, and patient quality of life. In addition, central mutational and genomic analysis of tumor tissue will be evaluated.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Sinonasal Carcinoma | Sinonasal Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Oncologic outcomes as measured by overall survival, disease specific survival and recurrence free survival
- timeFrame
- Through study completion, an average of 5 years
Secondary outcomes (2)
- measure
- Quality of life outcomes including the University of Washington Quality of Life Questionnaire (UW-QOL v4) and the Sinonasal Outcome Test 22 (SNOT22)
- timeFrame
- Through study completion, an average of 5 years
- measure
- Describe the molecular foundation of sinonasal malignancies utilizing RNA sequencing to identify transcriptomic tumor profiles
- timeFrame
- Through study completion, an average of 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 30 Days
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Subjects between the ages of 30 days (non-inclusive) and 99 years (inclusive) * Patients with a diagnosis of sinonasal cancer * Patients undergoing treatment at Mayo Clinic Exclusion Criteria: * Healthy individuals * Unwilling to sign the informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.