Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00655876 | Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer | completed | Phase 3 | 344 | Radiation Therapy Oncology GroupNETWORK | 2 | Jun 14, 2022 | clinicaltrials |
| NCT03623737 | Comparing Paclitaxel/Cisplatin and Cisplatin/5-fluorouracil in Neo-CRT for ESCC | unknown | Phase 2 / Phase 3 | 248 | National Taiwan University HospitalOTHER | 1 | Jun 7, 2022 | clinicaltrials |
| NCT04807673 | Pembrolizumab Plus Neoadjuvant Chemotherapy vs. Neoadjuvant Chemoradiotherapy for Locally Advanced ESCC (KEYSTONE-002)(KEYSTONE-002) | recruiting | Phase 3 | 342 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jun 1, 2022 | clinicaltrials |
| NCT01137123 | Improve the Treatment of Thoracic Esophageal Cancer | completed | Phase 3 | 301 | Sun Yat-sen UniversityOTHER | 1 | Mar 31, 2022 | clinicaltrials |
| NCT02459457 | A Comparison of Paclitaxel-based Three Regimens Concurrent With Radiotherapy for Patients With Local Advanced Esophageal Cancer | completed | Phase 3 | 321 | Fudan UniversityOTHER | 1 | Feb 9, 2022 | clinicaltrials |
| NCT04009265 | Study Compare Adjuvant Chemotherapy, Chemoradiotherapy and Surgery Alone for pN1-2(pT1b-3N1-2M0) Esophageal Carcinoma | recruiting | Phase 3 | 819 | Fujian Medical University Union HospitalOTHER | 1 | Nov 12, 2021 | clinicaltrials |
| NCT04196075 | The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer(AP) | completed | Phase 3 | 30 | Chinese University of Hong KongOTHER | 1 | Nov 8, 2021 | clinicaltrials |
| NCT05049681 | Study of Anti-PD-1 Antibody SHR-1210 Plus Apatinib vs SHR-1210 as Second-Line Treatment of Advanced Esophageal Squamous Cell | unknown | Phase 3 | 234 | Feng WangOTHER | 0 | Sep 20, 2021 | clinicaltrials |
| NCT04426955 | Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer | unknown | Phase 3 | 396 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Sep 16, 2021 | clinicaltrials |
| NCT00487695 | Confocal Endomicroscopy for Barrett's Esophagus(CEBE) | completed | Phase 3 | 46 | Johns Hopkins UniversityOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT02326779 | Low-dose Aspirin Therapy for Esophageal Cancer | withdrawn | Phase 3 | 0 | Zhejiang UniversityOTHER | 0 | Apr 27, 2021 | clinicaltrials |
| NCT02272699 | Neoadjuvant Treatment of Nimotuzumab With Chemotherapy or Radiotherapy in Resectable Esophageal Squamous Cell Carcinoma | withdrawn | Phase 2 / Phase 3 | 0 | Peking UniversityOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT00002883 | Surgery With or Without Combination Chemotherapy in Treating Patients With Cancer of the Esophagus | completed | Phase 3 | 250 | UNICANCEROTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT02644408 | Megestrol Acetate for the Improvement of Quality of Life in Esophageal Cancer With Chemoradiotherapy | completed | Phase 3 | 184 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT01107639 | Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery | completed | Phase 3 | 297 | Swiss Cancer InstituteOTHER | 5 | Oct 20, 2020 | clinicaltrials |
| NCT02813967 | S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer | completed | Phase 3 | 298 | Zhejiang Cancer HospitalOTHER | 1 | Sep 16, 2020 | clinicaltrials |
| NCT00020787 | Vaccine Therapy Plus Chemotherapy in Treating Patients With Metastatic or Locally Recurrent Stomach Cancer or Esophageal Cancer | completed | Phase 3 | 8 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00052910 | Chemotherapy and Radiation Therapy After Surgery in Treating Patients With Stomach or Esophageal Cancer | completed | Phase 3 | 546 | Alliance for Clinical Trials in OncologyOTHER | 2 | May 7, 2020 | clinicaltrials |
| NCT02279134 | Phase II/III Study Compare Adjuvant Chemoradiotherapy, Radiotherapy and Surgery Alone for Esophageal Carcinoma | unknown | Phase 2 / Phase 3 | 360 | Zefen XiaoUNKNOWN | 1 | Apr 3, 2020 | clinicaltrials |
| NCT00047112 | Surgery With or Without Radiation Therapy and Chemotherapy in Treating Patients With Esophageal Cancer | completed | Phase 3 | 195 | Federation Francophone de Cancerologie DigestiveOTHER | 4 | Mar 30, 2020 | clinicaltrials |
| NCT01544790 | Robot-assisted Thoraco-laparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy(ROBOT) | completed | Phase 3 | 112 | UMC UtrechtOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT02399306 | Chemoradiotherapy With or Without Enteral Nutrition for Locally Advanced Thoracic Esophageal Carcinoma | completed | Phase 3 | 222 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT03094351 | Robot-assisted Esophagectomy Versus Conventional Thoracoscopic Esophagectomy(RAE vs CTE) | unknown | Phase 3 | 360 | Shanghai Chest HospitalOTHER | 1 | Feb 5, 2020 | clinicaltrials |
| NCT01348217 | Radiochemotherapy With and Without Dose Escalation in Patients Presenting Locally Advanced or Inoperable Carcinoma of the Oesophagus(CONCORDE) | completed | Phase 2 / Phase 3 | 196 | Centre Georges Francois LeclercOTHER | 1 | Jan 27, 2020 | clinicaltrials |
| NCT04135664 | Comparison of Esophagectomy and Chemoradiation for Patients With cN0-pT1b Stage Esophageal Squamous Cell Carcinoma | recruiting | Phase 3 | 176 | Shanghai Chest HospitalOTHER | 1 | Oct 22, 2019 | clinicaltrials |
| NCT03731442 | Salvage Chemoradiation Therapy for Recurrence After Radical Surgery or Palliative Surgery in Esophageal Cancer Patients | recruiting | Phase 3 | 300 | Chinese Academy of Medical SciencesOTHER | 1 | Dec 12, 2018 | clinicaltrials |
| NCT01446874 | Prevention of Post-operative Pneumonia (POPP)(POPP) | terminated | Phase 2 / Phase 3 | 150 | Washington University School of MedicineOTHER | 1 | Nov 8, 2018 | clinicaltrials |
| NCT01591135 | A Phase III Study of Comparing Paclitaxel Plus 5-Fluorouracil Versus Cisplatin Plus 5-Fluorouracil in Chemoradiotherapy for Locally Advanced Esophageal Carcinoma | completed | Phase 3 | 436 | Fudan UniversityOTHER | 1 | Oct 18, 2018 | clinicaltrials |
| NCT03708042 | A Study to Compare Efficacy and Safety of DRT VS CRT Plus Surgery in Patients Who Achieved CCR for Esophageal Cancer | unknown | Phase 3 | 220 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Oct 16, 2018 | clinicaltrials |
| NCT01627379 | Cisplatin and 5-FU +/- Panitumumab for Patients With Nonresectable,Advanced or Metastatic Esophageal Squamous Cell Cancer(POWER) | terminated | Phase 3 | 300 | AIO-Studien-gGmbHOTHER | 1 | Mar 2, 2018 | clinicaltrials |
| NCT03366883 | Paclitaxel, Cisplatin,5-FU vs. Radiotherapy Plus Paclitaxel, Cisplatin as Preoperative Therapy for Locally Advanced ESC | unknown | Phase 3 | 420 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jan 9, 2018 | clinicaltrials |
| NCT03273647 | Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma With Positive Circumstantial Resection Margin | unknown | Phase 3 | 60 | Fudan UniversityOTHER | 0 | Oct 19, 2017 | clinicaltrials |
| NCT03273686 | Efficacy of Nasogastric Tube Application in Postoperative Care of Esophagectomy | unknown | Phase 3 | 100 | Fudan UniversityOTHER | 0 | Sep 6, 2017 | clinicaltrials |
| NCT01740375 | Role of Esophagectomy in Complete Responders to CCRT(ESOPRESSO) | terminated | Phase 3 | 486 | Asan Medical CenterOTHER | 1 | Aug 29, 2017 | clinicaltrials |
| NCT00160875 | Pre-operative Chemo (CPT11, Cisplatin), Radiotherapy, Plus Surgery for Resectable Esophageal Cancer | completed | Phase 2 / Phase 3 | 54 | University Health Network, TorontoOTHER | 1 | May 4, 2017 | clinicaltrials |
| NCT01704690 | Combination Treatment of S-1 With Paclitaxel in Advanced Esophageal Cancer | terminated | Phase 2 / Phase 3 | 4 | Peking UniversityOTHER | 1 | Apr 7, 2017 | clinicaltrials |
| NCT01216527 | Phase III Study of Neo-adjuvant Chemoradiotherapy Followed by Surgery for Squamous Cell Esophageal Cancer | unknown | Phase 3 | 430 | Sun Yat-sen UniversityOTHER | 1 | Feb 27, 2017 | clinicaltrials |
| NCT02604615 | The Role of Different Cycles of Chemotherapy（Capecitabine-oxaliplatin） in Esophageal Chemoradiotherapy(DCOECRT) | unknown | Phase 3 | 60 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Jul 6, 2016 | clinicaltrials |
| NCT00003118 | Surgery With or Without Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus | completed | Phase 3 | 56 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 4, 2016 | clinicaltrials |
| NCT02677597 | Cisplatin Combined With S-1 or Paclitaxel as First-line Treatment for Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 268 | Fudan UniversityOTHER | 1 | Feb 9, 2016 | clinicaltrials |
| NCT02611700 | Nimotuzumab in Combined With Paclitaxel and Cisplatin for Treatment of Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 504 | Biotech Pharmaceutical Co., Ltd.OTHER | 1 | Feb 1, 2016 | clinicaltrials |
| NCT02607540 | Different Cycles of Cisplatin-5-fluorouracil for the Chemoradiotherapy of Esophageal Squamous Cancer(PFCRTESC) | unknown | Phase 3 | 210 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Jan 12, 2016 | clinicaltrials |
| NCT01242124 | Impact of the Techniques for Intrathoracic Esophagogastric Anastomosis on Outcome in Ivor-Lewis Oesophagectomy | unknown | Phase 2 / Phase 3 | 40 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Dec 22, 2015 | clinicaltrials |
| NCT00861094 | Radiation Therapy + Combination Chemotherapy as 1st-Line Therapy for Patients With Inoperable Esophageal Cancer | completed | Phase 2 / Phase 3 | 266 | UNICANCEROTHER | 1 | Dec 18, 2015 | clinicaltrials |
| NCT02628665 | Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer | unknown | Phase 3 | 40 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Dec 11, 2015 | clinicaltrials |
| NCT01998347 | Paclitaxel Liposome and Cisplatin as First-line Chemotherapy in Patients With Metastatic Esophageal Cancer | withdrawn | Phase 3 | 0 | Shantou University Medical CollegeOTHER | 1 | Nov 20, 2015 | clinicaltrials |
| NCT02603159 | Different Cycles of Capecitabine Usage in Esophageal Cancer Concurrent Chemoradiotherapy(DCECRT) | unknown | Phase 3 | 200 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Nov 11, 2015 | clinicaltrials |
| NCT01998230 | Early Oral Feeding Following Thoracolaparoscopic Oesophagectomy in Patients With Esophageal Cancer | completed | Phase 3 | 280 | Yin LiOTHER_GOV | 1 | Oct 16, 2015 | clinicaltrials |
| NCT02570893 | A Phase III Trail of Adjuvant Chemoradiotherapy Versus Adjuvant Radiotherapy in Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 366 | Zhejiang Cancer HospitalOTHER | 1 | Oct 7, 2015 | clinicaltrials |
| NCT02461043 | Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Adjuvant Chemotherapy in the Treatment of the Lymph Node Positive Thoracic Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 386 | Chinese Academy of Medical SciencesOTHER | 1 | Sep 1, 2015 | clinicaltrials |
Data updated 22 days agoSource updated Jun 14, 2022source: clinicaltrials