Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03187314 | Combination of Radiation Therapy and Anti-PD-1 Antibody SHR-1210 in Treating Patients With Esophageal Cancer | completed | Phase 2 | 25 | Hangzhou Cancer HospitalOTHER | 1 | Aug 17, 2020 | clinicaltrials |
| NCT04512417 | A Clinical Study Of Camrelizumab With Or Without Radiotherapy In The Treatment Of Esophageal Cancer | unknown | Phase 2 | 63 | Zhejiang Cancer HospitalOTHER | 1 | Aug 13, 2020 | clinicaltrials |
| NCT04503967 |
| Efficacy and Safety of Anlotinib Hydrochloride Combined With Nivolumab in the Treatment of Gastric and Esophageal Cancer(OASIS) |
| unknown |
| Phase 2 |
| 48 |
| Shanghai Zhongshan HospitalOTHER |
| 0 |
| Aug 7, 2020 |
| clinicaltrials |
| NCT04504565 | 99m Tc-3PRGD2 SPECT/CT Imaging in the Diagnosis of Lymph Node Metastasis of Esophageal Carcinoma | unknown | N/A | 30 | Fifth Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 1 | Aug 7, 2020 | clinicaltrials |
| NCT00985192 | Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach Cancer | completed | Phase 2 | 49 | Translational Oncology Research InternationalOTHER | 1 | Aug 5, 2020 | clinicaltrials |
| NCT00003748 | Irinotecan in Treating Patients With Esophageal or Stomach Cancer | completed | Phase 2 | 40 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00020761 | Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus or Stomach | completed | Phase 2 | 51 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00020787 | Vaccine Therapy Plus Chemotherapy in Treating Patients With Metastatic or Locally Recurrent Stomach Cancer or Esophageal Cancer | completed | Phase 3 | 8 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00727376 | Evaluation of Polyflex Stenting in Esophageal Cancer Patients | completed | — | 26 | University of LouisvilleOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT02744729 | 99mTc-3PRGD2 SPECT/CT in Esophagus Cancer Patients | completed | Early Phase 1 | 29 | First Affiliated Hospital of Fujian Medical UniversityOTHER | 1 | Aug 3, 2020 | clinicaltrials |
| NCT00898495 | Genes in Predicting Outcome in Patients With Esophageal Cancer Treated With Cisplatin, Radiation Therapy, and Surgery | completed | — | 118 | ECOG-ACRIN Cancer Research GroupNETWORK | 0 | Jul 31, 2020 | clinicaltrials |
| NCT01249443 | Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection | terminated | Phase 1 | 17 | AIDS Malignancy ConsortiumNETWORK | 1 | Jul 29, 2020 | clinicaltrials |
| NCT03032224 | Analysis of Body Composition in Relation to Outcome After Surgery in a Cohort of Patients With Esophageal Cancer | completed | — | 76 | Vastra Gotaland RegionOTHER_GOV | 1 | Jul 28, 2020 | clinicaltrials |
| NCT03066167 | Validation of Instruments Used for Assessment of Dysphagia in Patients With Esophageal Cancer | completed | — | 64 | Vastra Gotaland RegionOTHER_GOV | 1 | Jul 28, 2020 | clinicaltrials |
| NCT03507998 | Phase 1 Dose Escalation Study of CGX1321 in Subjects With Advanced Gastrointestinal Tumors | unknown | Phase 1 | 39 | Curegenix Inc.INDUSTRY | 1 | Jul 24, 2020 | clinicaltrials |
| NCT03734926 | A Phase 1 Study of ZSP1241 in Participants With Advanced Solid Tumors | unknown | Phase 1 | 90 | Guangdong Zhongsheng Pharmaceutical Co., Ltd.INDUSTRY | 1 | Jul 22, 2020 | clinicaltrials |
| NCT02120911 | Feasibility Study of Chemoradiation, TRAstuzumab and Pertuzumab in Resectable HER2+ Esophageal Carcinoma(TRAP) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Jul 1, 2020 | clinicaltrials |
| NCT04437212 | Neoadjuvant Chemoradiotherapy Combined With Perioperative Toripalimab in Locally Advanced Esophageal Cancer | unknown | Phase 2 | 20 | RenJi HospitalOTHER | 1 | Jun 26, 2020 | clinicaltrials |
| NCT04440332 | Surveillance of Peripheral Blood of Lymphocyte and Immunocyte in Neoadjuvant Therapy Patients With Esophageal Squamous Cell Carcinoma (pLINE) | unknown | — | 138 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Jun 19, 2020 | clinicaltrials |
| NCT02138929 | LDE225 + Everolimus in Advanced Gastroesophageal Adenocarcinoma | completed | Phase 1 | 25 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT04229524 | Quantitative Assessment of Blood Supply in the Gastic Conduit With Fluorescence Angiography for Esophageal Reconstruction | unknown | N/A | 246 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Jun 9, 2020 | clinicaltrials |
| NCT01102088 | Simultaneous Integrated Boost (SIB) in Esophageal Cancer | completed | Phase 1 | 61 | M.D. Anderson Cancer CenterOTHER | 1 | May 22, 2020 | clinicaltrials |
| NCT02047305 | Radiofrequency Ablation for Patients With Esophageal Squamous Cell Neoplasia | completed | N/A | 96 | Covidien, GI SolutionsINDUSTRY | 1 | May 21, 2020 | clinicaltrials |
| NCT03418298 | Prehabilitation in Patients With Esophageal or Gastric Cancers | completed | N/A | 30 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | May 21, 2020 | clinicaltrials |
| NCT02017600 | A Phase II Trial of Induction Chemotherapy With ND-420, Cisplatin and Fluorouracil Followed by Surgery in the Treatment of Patients With Localized Squamous Cell Carcinoma of the Esophagus | terminated | Phase 2 | 48 | Nang Kuang Pharmaceutical Co., Ltd.INDUSTRY | 1 | May 20, 2020 | clinicaltrials |
| NCT03206125 | NCI UNC Project ESCC | terminated | — | 648 | National Cancer Institute (NCI)NIH | 1 | May 20, 2020 | clinicaltrials |
| NCT01913639 | FOLFOX Plus Regorafenib in Patients With Unresectable or Metastatic Esophagogastric Cancer | completed | Phase 2 | 39 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT02964455 | Study of Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 12 | Sun Yat-sen UniversityOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT03087864 | PDL-1 Targeting in Resectable Oesophageal Cancer(PERFECT) | completed | Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | May 11, 2020 | clinicaltrials |
| NCT00052910 | Chemotherapy and Radiation Therapy After Surgery in Treating Patients With Stomach or Esophageal Cancer | completed | Phase 3 | 546 | Alliance for Clinical Trials in OncologyOTHER | 2 | May 7, 2020 | clinicaltrials |
| NCT00901173 | A Pilot for a Case-Control Study of Esophageal Squamous Cell Carcinoma in Western Kenya | completed | — | 372 | National Cancer Institute (NCI)NIH | 1 | Apr 24, 2020 | clinicaltrials |
| NCT04269083 | A Biomarker-driven Therapeutic Strategy for Esophageal Cancer Chemoradiotherapy in Patients With Resectable Adenocarcinoma of the ESophagus and Esophagogastric Junction(BoRgES) | unknown | N/A | 128 | Azienda Ospedaliera Universitaria Integrata VeronaOTHER | 0 | Apr 17, 2020 | clinicaltrials |
| NCT02279134 | Phase II/III Study Compare Adjuvant Chemoradiotherapy, Radiotherapy and Surgery Alone for Esophageal Carcinoma | unknown | Phase 2 / Phase 3 | 360 | Zefen XiaoUNKNOWN | 1 | Apr 3, 2020 | clinicaltrials |
| NCT00047112 | Surgery With or Without Radiation Therapy and Chemotherapy in Treating Patients With Esophageal Cancer | completed | Phase 3 | 195 | Federation Francophone de Cancerologie DigestiveOTHER | 4 | Mar 30, 2020 | clinicaltrials |
| NCT01544790 | Robot-assisted Thoraco-laparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy(ROBOT) | completed | Phase 3 | 112 | UMC UtrechtOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT03061370 | Sarcopenia and Visceral Obesity in Esophageal and Gastric Cancer | completed | — | 317 | St. James's Hospital, IrelandOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT03461341 | European iNvestigation of SUrveillance After Resection for Esophageal Cancer(ENSURE) | completed | — | 3,000 | St. James's Hospital, IrelandOTHER | 3 | Mar 26, 2020 | clinicaltrials |
| NCT00539617 | Chemotherapy & Erlotinib in Treating Patients w/ Esophageal or Gastroesophageal Cancer That Cannot Be Removed by Surgery | terminated | Phase 2 | 7 | University of California, San FranciscoOTHER | 1 | Mar 23, 2020 | clinicaltrials |
| NCT02123381 | Changes in Tumor Tissue and Serum Biomarkers Before and After Cetuximab Combined With Preoperative Radiotherapy in Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 100 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT02399306 | Chemoradiotherapy With or Without Enteral Nutrition for Locally Advanced Thoracic Esophageal Carcinoma | completed | Phase 3 | 222 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT04194463 | Maintaining Fitness During Neo-adjuvant Chemotherapy for Oesophago-gastric Cancer: a Feasibility Study(ChemoFit) | unknown | N/A | 40 | Newcastle-upon-Tyne Hospitals NHS TrustOTHER | 1 | Mar 12, 2020 | clinicaltrials |
| NCT01787006 | Definitive Radiochemotherapy Plus/Minus Cetuximab in Unresectable Locally Advanced Esophageal Cancer | completed | Phase 2 | 74 | University Hospital Schleswig-HolsteinOTHER | 1 | Mar 10, 2020 | clinicaltrials |
| NCT03515356 | Exercise to Reduce Chemotherapy-Induced Peripheral Neuropathy | completed | N/A | 54 | University of Michigan Rogel Cancer CenterOTHER | 1 | Mar 9, 2020 | clinicaltrials |
| NCT02946671 | Study of Pre-operative Combination Therapy With Mogamulizumab and Nivolumab Against Solid Cancer Patients | completed | Phase 1 | 16 | Osaka UniversityOTHER | 1 | Mar 6, 2020 | clinicaltrials |
| NCT03526328 | DCLK1 as a Marker/Indicator of Stem Cell Response in Barrett's Esophagus/Esophageal Adenocarcinoma | completed | — | 32 | University of OklahomaOTHER | 1 | Mar 6, 2020 | clinicaltrials |
| NCT01143545 | Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas | terminated | Phase 1 | 10 | National Cancer Institute (NCI)NIH | 1 | Mar 3, 2020 | clinicaltrials |
| NCT01362127 | Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia(NeoRes) | completed | Phase 2 | 181 | Karolinska University HospitalOTHER | 1 | Feb 26, 2020 | clinicaltrials |
| NCT00439608 | Cetuximab, Paclitaxel, Carboplatin & Radiation for Esoph, Gastroesoph & Gastric Cancer | completed | Phase 2 | 60 | Brown UniversityOTHER | 1 | Feb 17, 2020 | clinicaltrials |
| NCT00522795 | Neoadjuvant Paclitaxel Poliglumex, Cisplatin and Radiation for Esophageal Cancer: A Phase II Trial (CTI#X64001) | completed | Phase 2 | 40 | Brown UniversityOTHER | 1 | Feb 17, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Aug 17, 2020source: clinicaltrials