Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,263 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,110 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,003)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05111353 | Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery | completed | Phase 1 | 33 | Washington University School of MedicineOTHER | 1 | May 6, 2026 | clinicaltrials |
| NCT03336658 | Intratumoral Budding (ITB) in Preoperative Biopsies of Colon and Rectal Cancer(ITB) | completed | — | 150 | Insel Gruppe AG, University Hospital BernOTHER | 1 | May 5, 2026 |
| clinicaltrials |
| NCT03797326 | Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005) | completed | Phase 2 | 611 | Merck Sharp & Dohme LLCINDUSTRY | 17 | May 4, 2026 | clinicaltrials |
| NCT04358185 | Itacitinib in Advanced Hepatocellular Carcinoma(JAKaL) | completed | Phase 1 | 19 | Imperial College LondonOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT06152276 | SafeHeal Diverting Ileostomy Pivotal Study(SH-SOC23) | completed | — | 132 | SafeHeal IncINDUSTRY | 4 | May 4, 2026 | clinicaltrials |
| NCT02837263 | PI Pembro in Combination With Stereotactic Body Radiotherapy for Liver Metastatic Colorectal Cancer | completed | Phase 1 | 15 | University of Wisconsin, MadisonOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT04118114 | Phase II Study of PRL3-ZUMAB in Advanced Solid Tumors | completed | Phase 2 | 14 | National Cancer Centre, SingaporeOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT05180565 | Safe Anastomosis Feasibility Study(SAFE2019) | completed | N/A | 27 | SafeHeal IncINDUSTRY | 2 | May 1, 2026 | clinicaltrials |
| NCT06261047 | Radiotherapy Delays Second-line Drug Therapy for Oligo Progressive Primary Liver Cancer | completed | — | 36 | Shandong Cancer Hospital and InstituteOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT05004350 | A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer.(NAUTICALCRC) | completed | Phase 2 | 107 | Pierre Fabre MedicamentINDUSTRY | 1 | Apr 30, 2026 | clinicaltrials |
| NCT06212128 | RAPIDO vs LCRT vs Upfront Surgery - a Prospective Cohort Study(RAPIDO) | completed | — | 57 | Sengkang General HospitalOTHER | 0 | Apr 30, 2026 | clinicaltrials |
| NCT06866678 | Frailty Score and Postoperative Morbidity in Colorectal Cancer Surgery | completed | — | 200 | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research HospitalOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT07003061 | Sarcopenia and Neuromuscular Block in Gastrointestinal Cancer Surgery | completed | — | 100 | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research HospitalOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT04558398 | Impact of Exercise on Mitochondria in Cancer Patients.(ICCE-Mito) | completed | N/A | 15 | University of NottinghamOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT05014776 | Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer | completed | Phase 2 | 17 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT05535894 | Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer | completed | — | 19 | West Virginia UniversityOTHER | 1 | Apr 28, 2026 | clinicaltrials |
| NCT02299596 | Physical Activity in Relation to Surgical Procedures | completed | N/A | 761 | Sahlgrenska University HospitalOTHER | 1 | Apr 27, 2026 | clinicaltrials |
| NCT05085548 | ProAgio in Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies | completed | Phase 1 | 46 | ProDa BioTech, LLCINDUSTRY | 1 | Apr 27, 2026 | clinicaltrials |
| NCT06428487 | Neoadjuvant Prolgolimab Monotherapy in Locally Advanced MMR-deficient Colorectal Cancer | completed | Phase 2 | 30 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Apr 27, 2026 | clinicaltrials |
| NCT00819208 | Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer(CHALLENGE) | completed | N/A | 889 | Canadian Cancer Trials GroupNETWORK | 6 | Apr 24, 2026 | clinicaltrials |
| NCT02366286 | Hepatitis B and Hepatitis C as Risk Factors for Hepatocellular Carcinoma in African and Asian Immigrants | completed | — | 892 | Mayo ClinicOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT04868773 | Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy | completed | Phase 1 | 15 | University of California, IrvineOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT00885066 | Gemcitabine, Capecitabine, and Erlotinib in Treating Patients With Advanced Pancreatic Cancer | completed | Phase 1 | 30 | Centre Antoine LacassagneOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT01787500 | Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery | completed | Phase 1 | 47 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT05625893 | Proton Beam Radiotherapy Followed by Tecentriq and Avastin for Primary Liver Cancer With Vp2-4 Portal Vein Invasion | completed | Phase 2 | 63 | Samsung Medical CenterOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT00937456 | Open Versus Laparoscopically-assisted Esophagectomy for Cancer | completed | N/A | 207 | University Hospital, LilleOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT03138720 | Pre-operative Treatment for Patients With Untreated Pancreatic Cancer | completed | Phase 2 | 40 | HonorHealth Research InstituteOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT03981146 | A Phase II Trial Assessing Nivolumab in Class II Expressing Microsatellite Stable Colorectal Cancer(ANICCA) | completed | Phase 2 | 35 | University of BirminghamOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT05414448 | Combination of Artificial Intelligence and Mucosal Exposure Device to Enhance Colorectal Neoplasia Detection(AIDEN) | completed | N/A | 1,726 | Chinese University of Hong KongOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT02584985 | Evaluate Efficacy, Morbidity and Functional Outcome of Endoscopic TranAnal Proctectomy vs Standard Transabdominal Laparoscopic Proctectomy for Rectal Cancer(ETAP) | completed | Phase 3 | 226 | Institut Paoli-CalmettesOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT03213678 | Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) | completed | Phase 2 | 18 | National Cancer Institute (NCI)NIH | 2 | Apr 21, 2026 | clinicaltrials |
| NCT07542782 | Pancreatic Resection in Fit Octogenarians With Nonmetastatic Pancreatic Cancer(PRONPaC) | completed | — | 2,048 | Medizinische Hochschule Brandenburg Theodor FontaneOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT01899261 | Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery | completed | N/A | 20 | Montefiore Medical CenterOTHER | 1 | Apr 20, 2026 | clinicaltrials |
| NCT02437851 | Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection | completed | Phase 2 | 16 | AIDS Malignancy ConsortiumNETWORK | 1 | Apr 20, 2026 | clinicaltrials |
| NCT04128332 | Pre-operative Stereotactic Ablative Body Radiotherapy Followed by Immediate Surgery for Pancreatic Cancer(PORTICO-SABR) | completed | N/A | 10 | CCTU- Cancer ThemeOTHER | 1 | Apr 20, 2026 | clinicaltrials |
| NCT00373347 | Identification of New Serum Diagnostic Markers of Hepatocellular Carcinoma | completed | — | 573 | Stanford UniversityOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT03965325 | FOcUs on Colorectal CAncer oUtcomes: Long-Term Study(Foucault) | completed | — | 133 | IHU StrasbourgOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT04899739 | Intraoperative Endoscopic Ultrasound for Pancreatic Cancer(EchoSurg) | completed | N/A | 33 | IHU StrasbourgOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT05195970 | Walnuts and Colon Health | completed | N/A | 140 | UConn HealthOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT05332496 | TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Intermediate HCC(CHANCE2202) | completed | — | 941 | Zhongda HospitalOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT05332821 | TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Advanced HCC(CHANCE2201) | completed | — | 1,244 | Zhongda HospitalOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT06233981 | Phase II Study of Moderate-dose Hypofractionated RT Combined With Tislelizumab for HCC With Diffuse Tumor Thrombosis | completed | Phase 2 | 30 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT07101874 | A Study to Evaluate the Association of Biliary Complications and Treatment Duration in Unresectable BTC Patients(ARCBile) | completed | — | 729 | AstraZenecaINDUSTRY | 1 | Apr 17, 2026 | clinicaltrials |
| NCT02110329 | Simultaneaous Detection of Quantitative Somatic Alterations Using the Qantitative Multiplex Pcr of Short Fluorescent Fragments Method (QMPSF) in Stage II-III Colon Cancer: a Prospective Study(Code Barre) | completed | N/A | 401 | University Hospital, RouenOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT02557061 | Prognostic Value of the Lymphocytic Infiltrate in Colon Cancers(TIL) | completed | N/A | 56 | University Hospital, RouenOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT02872779 | Correlation Between Circulating Tumour Markers Early Variations and Clinical Response in First Line Treatment of Metastatic Colorectal Cancer(COCA-MACS) | completed | N/A | 74 | University Hospital, RouenOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT04355156 | Axitinib Monotherapy With Early Dynamic Contrast Enhanced Ultrasound Monitoring in Chemorefractory Third Line Metastatic Colorectal Cancer(AXMUS-C) | completed | Phase 2 | 52 | Imperial College LondonOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT04924062 | Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966)-China Extension Study | completed | Phase 3 | 158 | Merck Sharp & Dohme LLCINDUSTRY | 1 | Apr 15, 2026 | clinicaltrials |
Data updated 24 days agoSource updated May 6, 2026source: clinicaltrials