Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,259 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,094 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,000)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03623464 | RCT of Mobile Apps & FitBit v. Usual Care | suspended | N/A | 107 | Weill Medical College of Cornell UniversityOTHER | 1 | Sep 28, 2026 | clinicaltrials |
| NCT04031469 | A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease | suspended | — | 1,000 | ProgenaBiomeOTHER | 1 | Sep 21, 2026 | clinicaltrials |
| ARGONAUT: Stool and Blood Sample Bank for Cancer Patients |
| suspended |
| — |
| 5,000 |
| Persephone BiosciencesINDUSTRY |
| 1 |
| Sep 18, 2026 |
| clinicaltrials |
| NCT06039202 | CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Metastatic Colorectal Cancer | suspended | Phase 2 | 100 | Holy Stone Healthcare Co., LtdINDUSTRY | 1 | Sep 18, 2026 | clinicaltrials |
| NCT06968195 | Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma | suspended | Phase 1 | 24 | Roswell Park Cancer InstituteOTHER | 1 | Sep 15, 2026 | clinicaltrials |
| NCT04111172 | A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma | suspended | Phase 2 | 48 | Thomas Jefferson UniversityOTHER | 1 | Sep 14, 2026 | clinicaltrials |
| NCT05685602 | CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer | suspended | Phase 1 | 43 | National Cancer Institute (NCI)NIH | 1 | Sep 9, 2026 | clinicaltrials |
| NCT06050252 | Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery | suspended | Phase 2 | 27 | National Cancer Institute (NCI)NIH | 1 | Sep 4, 2026 | clinicaltrials |
| NCT07388563 | Azacitidine and Abatacept in Relapsed or Refractory T-Cell Lymphoma | suspended | Phase 1 | 20 | National Cancer Institute (NCI)NIH | 1 | Aug 26, 2026 | clinicaltrials |
| NCT06620302 | Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma | suspended | Phase 1 / Phase 2 | 81 | Children's Oncology GroupNETWORK | 1 | Aug 24, 2026 | clinicaltrials |
| NCT06250036 | Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer(ZODIAC) | suspended | Phase 2 | 50 | Royal Marsden NHS Foundation TrustOTHER | 1 | Aug 21, 2026 | clinicaltrials |
| NCT05494697 | Ampligen Combined With SOC Versus SOC Alone Following First-Line Therapy in Subjects With LAPC | suspended | Phase 2 | 90 | AIM ImmunoTech Inc.INDUSTRY | 1 | Aug 19, 2026 | clinicaltrials |
| NCT05791448 | AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease | suspended | Phase 1 | 36 | University of Southern CaliforniaOTHER | 1 | Aug 17, 2026 | clinicaltrials |
| NCT07057089 | Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I) | suspended | Phase 2 | 90 | Hebei Medical University Fourth HospitalOTHER | 1 | Jul 31, 2026 | clinicaltrials |
| NCT07377526 | TROP2 CAREngineered Cord Blood-Derived NK Cells + Belzutifan In Pancreatic Cancer | suspended | Phase 1 / Phase 2 | 37 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 31, 2026 | clinicaltrials |
| NCT05377827 | Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies | suspended | Phase 1 | 6 | Washington University School of MedicineOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT05400122 | Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer | suspended | Phase 1 | 12 | David WaldOTHER | 1 | Jul 14, 2026 | clinicaltrials |
| NCT05967533 | The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors | suspended | Phase 1 | 100 | University of California, DavisOTHER | 1 | Jul 1, 2026 | clinicaltrials |
| NCT04158635 | Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer | suspended | Phase 1 | 21 | City of Hope Medical CenterOTHER | 1 | Jun 15, 2026 | clinicaltrials |
| NCT05419479 | Switch Maintenance in Pancreatic | suspended | Phase 1 / Phase 2 | 46 | James Cleary, MD, PhDOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT06405061 | Evaluation of Effectiveness and Safety of HAIC in Combination With Adebrelimab and Bevacizumab for Potentially Resectable Hepatocellular Carcinoma | suspended | Phase 2 | 40 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | May 29, 2026 | clinicaltrials |
| NCT04975217 | Fecal Microbial Transplants for the Treatment of Pancreatic Cancer | suspended | Early Phase 1 | 10 | M.D. Anderson Cancer CenterOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT04955808 | Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery | suspended | — | 2,400 | National Cancer Institute (NCI)NIH | 1 | May 13, 2026 | clinicaltrials |
| NCT05200442 | A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer | suspended | Phase 1 / Phase 2 | 53 | University of ChicagoOTHER | 1 | May 8, 2026 | clinicaltrials |
| NCT04541381 | The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care | suspended | N/A | 860 | University of ChicagoOTHER | 1 | May 7, 2026 | clinicaltrials |
| NCT06653010 | Universal CAR-T Cells (REVO-UWD-01) for Metastatic Colorectal Cancer(Wondercel-UWD1) | suspended | Early Phase 1 | 30 | Wondercel Biotech (ShenZhen)INDUSTRY | 1 | May 7, 2026 | clinicaltrials |
| NCT06653023 | Universal CAR-T Cells (REVO-UWD-03) for Advanced Hepatocellular Carcinoma and Lung Cancer(Wondercel-UWD3) | suspended | Early Phase 1 | 60 | Wondercel Biotech (ShenZhen)INDUSTRY | 1 | May 7, 2026 | clinicaltrials |
| NCT06675513 | Autologous CAR-T Cells (WD-01) for Metastatic Colorectal Cancer | suspended | Early Phase 1 | 30 | Wondercel Biotech (ShenZhen)INDUSTRY | 1 | May 7, 2026 | clinicaltrials |
| NCT06653192 | EUS-guided Choledochoduodenostomy vs ERCP as First Line in Malignant Distal Obstruction (CARPEDIEM Trial) | suspended | N/A | 120 | Hospital Universitari de BellvitgeOTHER | 1 | May 6, 2026 | clinicaltrials |
| NCT04929015 | Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES Study) | suspended | N/A | 30 | Rutgers, The State University of New JerseyOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT07173374 | Stereotactic Centralized Ablative Radiotherapy for Locally Advanced Pancreatic Cancer: A Single-Arm Phase I Safety and Feasibility Study(SCART-P) | suspended | Phase 1 | 24 | Shandong Cancer Hospital and InstituteOTHER | 1 | May 1, 2026 | clinicaltrials |
| NCT04336202 | Watch and Wait Management on Rectal Cancer Patients Using New Swift Local Therapy(Whistle) | suspended | N/A | 45 | Sir Mortimer B. Davis - Jewish General HospitalOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT02366819 | Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer | suspended | Phase 4 | 36 | University of ChicagoOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT06281925 | Cryotherapy & Oxaliplatin | suspended | N/A | 40 | NYU Langone HealthOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT03065062 | Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors | suspended | Phase 1 | 75 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 13, 2026 | clinicaltrials |
| NCT05062889 | Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients(ERASE-CRC) | suspended | Phase 2 | 477 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Feb 3, 2026 | clinicaltrials |
| NCT05241210 | Real-Time Feedback (RTFB) to Improve Colonoscopy | suspended | N/A | 4,150 | University of MinnesotaOTHER | 1 | Dec 9, 2025 | clinicaltrials |
| NCT05358704 | Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer | suspended | Phase 2 | 38 | Rutgers, The State University of New JerseyOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT04392050 | A Community-Based Educational Intervention to Improve Colorectal Cancer Screening | suspended | — | 90 | Thomas Jefferson UniversityOTHER | 1 | Nov 28, 2025 | clinicaltrials |
| NCT05033522 | Immunotherapy for Advanced Liver Cancer(ALIVE) | suspended | Phase 2 / Phase 3 | 150 | Mirror Biologics, Inc.INDUSTRY | 2 | Oct 23, 2025 | clinicaltrials |
| NCT03417921 | A Study of ABTL0812 in Pancreatic Cancer(Pancreatic) | suspended | Phase 1 / Phase 2 | 60 | Ability Pharmaceuticals SLINDUSTRY | 1 | Oct 1, 2025 | clinicaltrials |
| NCT04693546 | Protocol to Validate the Performance of the LifeKit® Prevent Colorectal Neoplasia Test for CRC Screening(PREVENT) | suspended | — | 12,000 | Metabiomics CorpINDUSTRY | 1 | Sep 26, 2025 | clinicaltrials |
| NCT05591534 | Endorectal Brachytherapy for Rectal Cancer(ICUREC) | suspended | Phase 2 | 31 | University Hospital, BordeauxOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT06728657 | Preoperative HFRT Verses PULSAR for Locally Advanced GEJ or Proximal Gastric Adenocarcinoma(TORCH-G) | suspended | Phase 2 | 68 | Fudan UniversityOTHER | 1 | Jun 18, 2025 | clinicaltrials |
| NCT05603572 | KAT-101 in Subjects With Hepatocellular Carcinoma (HCC) | suspended | Phase 1 / Phase 2 | 148 | Primocure PharmaINDUSTRY | 1 | Jun 5, 2025 | clinicaltrials |
| NCT02311712 | Non-endoscopic EC Screening Program in Northern Iran(NESP) | suspended | N/A | 12,000 | Tehran University of Medical SciencesOTHER | 0 | Apr 16, 2025 | clinicaltrials |
| NCT05375708 | Systemic Therapy in Combination with Stereotactic Radiotherapy in Patients with Metastatic Colorectal Cancer Up to 10 Metastatic Sites(SIRIUS) | suspended | Phase 2 | 93 | UMC UtrechtOTHER | 1 | Mar 28, 2025 | clinicaltrials |
| NCT04268888 | Nivolumab in Combination With TACE/TAE for Patients With Intermediate Stage HCC(TACE-3) | suspended | Phase 2 / Phase 3 | 522 | The Clatterbridge Cancer Centre NHS Foundation TrustOTHER | 2 | Feb 26, 2025 | clinicaltrials |
| NCT05191667 | AN0025 and Chemoradiotherapy Combination in Esophageal Cancer | suspended | Phase 1 | 32 | Adlai Nortye Biopharma Co., Ltd.INDUSTRY | 1 | Feb 13, 2025 | clinicaltrials |
| NCT02935478 | Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation | suspended | N/A | 8 | St. Louis UniversityOTHER | 1 | Feb 6, 2025 | clinicaltrials |
Data updated 22 hours agoSource updated Sep 28, 2026source: clinicaltrials