Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,108 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,001)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07653451 | Precision Medicine for Immunotherapy-Resistant Advanced Esophageal Cancer(ESCC-PT) | not yet recruiting | Phase 2 / Phase 3 | 90 | Peking University Cancer Hospital & InstituteOTHER | 0 | Jun 17, 2026 | clinicaltrials |
| NCT07558304 | Suprapapillary Metal Stent vs. Routine Transpapillary Drainage in Malignant Hilar Biliary Obstruction (SMART-B Trial)(SMART-B) | not yet recruiting | N/A | 84 | Hospital de Clinicas de Porto AlegreOTHER |
| 1 |
| Jun 16, 2026 |
| clinicaltrials |
| NCT07649473 | QL1706 Combined With Standard Therapy for Conversion Therapy of Synchronous Liver Metastases From Colon Cancer: a Multicenter, Single-arm, Exploratory Study | not yet recruiting | Phase 2 | 30 | Fujian Medical UniversityOTHER | 1 | Jun 16, 2026 | clinicaltrials |
| NCT07649980 | Becotatug Vedotin Plus Pucotenlimab for Advanced Biliary Tract Cancer, Phase II | not yet recruiting | Phase 2 | 30 | HuiKai LiOTHER | 0 | Jun 16, 2026 | clinicaltrials |
| NCT07650357 | A Study of CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101) | not yet recruiting | Phase 1 | 140 | Clasp Therapeutics, Inc.INDUSTRY | 1 | Jun 16, 2026 | clinicaltrials |
| NCT07651007 | Short-course RT Followed by NALIRIFOX Plus Pucotenlimab as Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer With MSS/pMMR | not yet recruiting | Phase 2 | 29 | Wang XinOTHER | 0 | Jun 16, 2026 | clinicaltrials |
| NCT07648589 | Glucose Homeostasis and Shared Genetic Factors in Colorectal Cancer(BRIDGE-CRCDM) | not yet recruiting | — | 200 | Chang Gung Memorial HospitalOTHER | 0 | Jun 15, 2026 | clinicaltrials |
| NCT07612007 | HRX215, A First Generation MKK4 Inhibitor Drug, for the Treatment of Patients With Colorectal Liver Metastasis After Undergoing a Portal Vein Embolization | not yet recruiting | Phase 2 | 80 | Mayo ClinicOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT07638956 | ICG in Colon Cancer(ICG) | not yet recruiting | N/A | 25 | Tanta UniversityOTHER | 0 | Jun 12, 2026 | clinicaltrials |
| NCT07644208 | PD-1/IL-2 Bispecific Antibody as Neoadjuvant Therapy for Early Recurrent Hepatocellular Carcinoma After Curative Hepatectomy | not yet recruiting | Phase 2 | 30 | Shanghai Zhongshan HospitalOTHER | 0 | Jun 12, 2026 | clinicaltrials |
| NCT07645118 | Brachytherapy Followed by Nivolumab Prior to Surgery in Rectal Cancer(IMPERIA) | not yet recruiting | Phase 2 | 10 | Dr. Te VuongOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT07318389 | ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer | not yet recruiting | Early Phase 1 | 100 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 11, 2026 | clinicaltrials |
| NCT07642323 | Safety and Efficacy of NOM and OPFS Versus RO for dMMR/MSI-H or POLE-Mutated Gastrointestinal Cancers(NOR-MP) | not yet recruiting | — | 22 | Peking University Cancer Hospital & InstituteOTHER | 0 | Jun 11, 2026 | clinicaltrials |
| NCT07637786 | Peptide Nanovaccine (ONVAX-01) Plus Anti-PD-1 Antibody and Chemotherapy in Advanced Pancreatic Cancer | not yet recruiting | Phase 1 | 9 | Sichuan UniversityOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT07638501 | Efficacy and Safety of SBRT Plus Gemcitabine, Cisplatin, and Sintilimab as First-Line Treatment for Unresectable Biliary Tract Cancer | not yet recruiting | Phase 2 | 123 | Eastern Hepatobiliary Surgery HospitalOTHER | 1 | Jun 10, 2026 | clinicaltrials |
| NCT07638631 | Ipilimumab (N01) Plus Sintilimab and Modified XELOX as Conversion Therapy in Unresectable Locally Advanced Gastric Cancer(DIAMC-GC) | not yet recruiting | Phase 2 | 30 | Chen LizhuOTHER_GOV | 0 | Jun 10, 2026 | clinicaltrials |
| NCT07639801 | 68Ga-FAPI-PSMA PET Imaging for the Diagnosis of Solid Tumors | not yet recruiting | N/A | 20 | Peking University Cancer Hospital & InstituteOTHER | 0 | Jun 10, 2026 | clinicaltrials |
| NCT07639970 | Evaluation of [⁶⁸Ga/¹⁷⁷Lu]HT547: Safety, Biodistribution, and Dosimetry in Solid Tumors | not yet recruiting | Early Phase 1 | 20 | Hua PangOTHER | 0 | Jun 10, 2026 | clinicaltrials |
| NCT06446557 | De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer(DIAMOND) | not yet recruiting | Phase 3 | 408 | University Hospital, RouenOTHER | 1 | Jun 9, 2026 | clinicaltrials |
| NCT07306390 | Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)(DIAMOND) | not yet recruiting | — | 1,200 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jun 9, 2026 | clinicaltrials |
| NCT06882915 | Efficacy and Safety of Trifluridine/Tipiracil (TAS-102) Combined With Bevacizumab and Serplulimab in Patients With Metastatic Colorectal Cancer Undergoing Cytoreductive Surgery: A Single-Arm, Single-Center Clinical Study | not yet recruiting | Phase 1 | 20 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Jun 8, 2026 | clinicaltrials |
| NCT07623642 | A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors. | not yet recruiting | Phase 2 | 227 | GV20 TherapeuticsINDUSTRY | 1 | Jun 8, 2026 | clinicaltrials |
| NCT07632313 | Health Behavior Intervention for Colorectal Cancer Patients | not yet recruiting | N/A | 40 | Nanjing Medical UniversityOTHER | 1 | Jun 8, 2026 | clinicaltrials |
| NCT07629193 | Liver Transplant for Hepatocellular Carcinoma(TH-CHC) | not yet recruiting | — | 562 | Assistance Publique - Hôpitaux de ParisOTHER | 0 | Jun 5, 2026 | clinicaltrials |
| NCT07611071 | AI-Integrated Emotional Granularity Training for Resilience and Quality of Life in Colorectal Cancer Survivors | not yet recruiting | N/A | 54 | The Hong Kong Polytechnic UniversityOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT07622550 | A Single-arm, Multicenter Clinical Study of Fruquintinib Combined With Serplulimab and Chemotherapy as First-line Treatment for Patients With RAS/BRAF-mutated Advanced Colorectal Cance | not yet recruiting | Phase 2 | 80 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Jun 3, 2026 | clinicaltrials |
| NCT07624214 | Study of LT-010391 in Participants With KRAS G12D-Mutant Solid Tumors | not yet recruiting | Phase 1 | 198 | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd.INDUSTRY | 1 | Jun 3, 2026 | clinicaltrials |
| NCT07624916 | Transversus Abdominis Plane and Rectus Sheath Block for Robotic Colectomy | not yet recruiting | Phase 4 | 90 | Tri-Service General Hospital (TSGH)OTHER | 1 | Jun 3, 2026 | clinicaltrials |
| NCT06914011 | Circulating Tumor DNA MRD-Guided Adjuvant Therapy for Curatively Resected Locally Advanced Esophageal Squamous Cell Carcinoma(MRD2START) | not yet recruiting | Phase 3 | 172 | Asan Medical CenterOTHER | 0 | Jun 2, 2026 | clinicaltrials |
| NCT07319104 | Liquid Biopsy in Early Colorectal Lesions(FECCO-BioBank) | not yet recruiting | — | 1,000 | University Hospital, MontpellierOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07620080 | EYEMAX® Versus SPYGLASS™ DS for Biliary Stricture Diagnosis(EYE/SPY) | not yet recruiting | N/A | 120 | David KARSENTIOTHER | 0 | Jun 2, 2026 | clinicaltrials |
| NCT07620743 | Noninvasive Early Diagnosis of Colorectal Cancer Using Odor-Targeted Capture, Point-of-Care Testing, and Intelligent Analysis | not yet recruiting | — | 453 | Beijing University of Chinese MedicineOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07621029 | Venous Resection in Patients Undergoing Pancreatic Surgery(VENUS) | not yet recruiting | — | 1,000 | Sahlgrenska University HospitalOTHER | 2 | Jun 2, 2026 | clinicaltrials |
| NCT07621497 | FOLFOX8 Versus mFOLFOX6 With Bevacizumab or Cetuximab for First-Line Unresectable Metastatic Colorectal Cancer (Phase II) | not yet recruiting | Phase 2 | 229 | Sun Yat-sen UniversityOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07621562 | Tafolecimab Combined With Sintilimab and SOX in the Treatment of pMMR/MSS Gastric Cancer | not yet recruiting | Phase 2 | 30 | First Affiliated Hospital of Zhejiang UniversityOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07621601 | A Study of HS-20093 in Patients With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) | not yet recruiting | Phase 3 | 494 | Hansoh BioMedical R&D CompanyINDUSTRY | 0 | Jun 2, 2026 | clinicaltrials |
| NCT07622017 | KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal Cancer(K-BOOST) | not yet recruiting | Phase 2 | 24 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07618546 | A Multicenter, Randomized, Open-label, Controlled Study of HAIC Combined With Camrelizumab and Apatinib Mesylate for Perioperative Treatment of Resectable Hepatocellular Carcinoma With High-risk Recurrence Factors | not yet recruiting | N/A | 208 | Henan Cancer HospitalOTHER_GOV | 0 | Jun 1, 2026 | clinicaltrials |
| NCT07618910 | Retlirafusp Alfa Plus Chemotherapy as Neoadjuvant Therapy for Thoracic ESCC | not yet recruiting | Phase 2 | 33 | Tang-Du HospitalOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT07615907 | A Study on the Efficacy of Sodium Propionate Combined With Anti-PD-1 Immunotherapy in Gastric Cancer(PAPGC) | not yet recruiting | N/A | 20 | Jinling Hospital, ChinaOTHER | 1 | May 29, 2026 | clinicaltrials |
| NCT07605312 | AI-Based Risk Prediction Model for Upper Digestive Tract Cancer | not yet recruiting | — | 10,000 | National Taiwan University HospitalOTHER | 0 | May 28, 2026 | clinicaltrials |
| NCT07610629 | Retlirafusp Alfa Combined With Apatinib and Nab-Paclitaxel as Second-line Treatment for Gastric or Gastroesophageal Junction Cancer(RA-A-NP) | not yet recruiting | Phase 2 | 50 | Henan Cancer HospitalOTHER_GOV | 1 | May 28, 2026 | clinicaltrials |
| NCT07612566 | Immune Repertoire Decoding for Chronic Pancreatitis-to-Pancreatic Cancer Risk Stratification | not yet recruiting | — | 800 | Changhai HospitalOTHER | 0 | May 28, 2026 | clinicaltrials |
| NCT07495579 | Lenvatinib or Regorafenib for Advanced Hepatocellular Carcinoma After Immunotherapy (REVIVE)(REVIVE) | not yet recruiting | Phase 2 | 146 | Asan Medical CenterOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT07608627 | 64Cu-DOTA A2 scFv-Fc2 DM With Positron Emission Tomography for the Imaging of Patients With Locally Advanced or Metastatic PSCA-Expressing Pancreatic Cancer | not yet recruiting | Phase 1 | 15 | City of Hope Medical CenterOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT06528353 | Blood Biomarkers Based Screening for HPV-driven OPC(SCREEN-HPV) | not yet recruiting | N/A | 10,000 | UNICANCEROTHER | 0 | May 26, 2026 | clinicaltrials |
| NCT07284394 | Liver-directed Chemotherapy After Surgery of Liver Metastases of Colorectal Cancer in Patients With High Risk of Recurrence of Their Disease(PACHA-02) | not yet recruiting | Phase 3 | 272 | UNICANCEROTHER | 0 | May 26, 2026 | clinicaltrials |
| NCT07605702 | The Canopy Cancer Collective Clinical Registry Protocol | not yet recruiting | — | 100,000 | Canopy Cancer Collective, LLCNETWORK | 1 | May 26, 2026 | clinicaltrials |
| NCT07606430 | Comparison of a Short Modified Metal Stent Versus Plastic Stent as a Bridge to Surgery in Pancreatic Cancer With Malignant Biliary Obstruction(BRIDGE-8) | not yet recruiting | N/A | 116 | Soonchunhyang University HospitalOTHER | 0 | May 26, 2026 | clinicaltrials |
| NCT06890624 | mFOLFOXIRI Plus PD-1 Inhibitor vs mFOLFOX6 as Neoadjuvant Therapy for Locally Advanced Colon Cancer(OPTICAL-3) | not yet recruiting | Phase 2 | 138 | Sun Yat-sen UniversityOTHER | 0 | May 22, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Jun 17, 2026source: clinicaltrials