Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,101 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,000)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07242820 | Reducing Neoplasia Recurrence After Non-thermal Endoscopic Resection of Large Colorectal Polyps(COSA-RCT) | not yet recruiting | N/A | 752 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Aug 14, 2026 | clinicaltrials |
| NCT07700212 | A Phase 1 Trial Of Safety And Initial Efficacy Of Vagal Nerve Blockade For Cancer-Induced Cachexia In Patients With Metastatic Pancreatic Adenocarcinoma | not yet recruiting | Phase 1 | 10 | M.D. Anderson Cancer CenterOTHER |
| 1 |
| Aug 14, 2026 |
| clinicaltrials |
| NCT07764523 | Home-based Whole Course Multimodal Prehabilitation Based on 5G + Artificial Intelligence Mobile Health(mHealth prehab) | not yet recruiting | N/A | 328 | The Affiliated Hospital of Qingdao UniversityOTHER | 1 | Aug 14, 2026 | clinicaltrials |
| NCT07764835 | Prospective Evaluation of Hepatocellular Carcinoma Surveillance in At-Risk Patients (Screening HCC)(Screening HCC) | not yet recruiting | — | 300 | D'Or Institute for Research and EducationOTHER | 0 | Aug 14, 2026 | clinicaltrials |
| NCT07765433 | Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract Cancer | not yet recruiting | Phase 2 / Phase 3 | 336 | ECOG-ACRIN Cancer Research GroupNETWORK | 0 | Aug 14, 2026 | clinicaltrials |
| NCT07765667 | NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC(CRI-KEV) | not yet recruiting | Phase 2 | 100 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Aug 14, 2026 | clinicaltrials |
| NCT07762950 | Blood Biomarkers and Gut Microbiota for Pancreatic Cancer Risk in Chronic Pancreatitis | not yet recruiting | — | 800 | Changhai HospitalOTHER | 0 | Aug 13, 2026 | clinicaltrials |
| NCT07764120 | Quality of Life of Patients After Rectal Cancer Resection .(QRAAP) | not yet recruiting | — | 22 | University Hospital, GrenobleOTHER | 0 | Aug 13, 2026 | clinicaltrials |
| NCT07272642 | A Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tumors.(DUNP19) | not yet recruiting | Phase 1 | 16 | Radiopharm Theranostics, LtdINDUSTRY | 1 | Aug 12, 2026 | clinicaltrials |
| NCT07761169 | Randomized Controlled Trial of the SurgDiff Model for Predicting Surgical Difficulty to Help Choose Approach in Mid-Low Rectal Cancer | not yet recruiting | N/A | 68 | Peking Union Medical College HospitalOTHER | 0 | Aug 12, 2026 | clinicaltrials |
| NCT07761286 | Evaluate the Safety and Efficacy of Combination Therapy With SYS6090 Injection for Hepatocellular Carcinoma | not yet recruiting | Phase 1 / Phase 2 | 288 | CSPC Megalith Biopharmaceutical Co.,Ltd.INDUSTRY | 1 | Aug 12, 2026 | clinicaltrials |
| NCT07757022 | AI-Driven Digital Twin and Drug Simulation for Esophageal Cancer(ESCA-DT) | not yet recruiting | — | 400 | Henan Cancer HospitalOTHER_GOV | 0 | Aug 11, 2026 | clinicaltrials |
| NCT07754513 | Circulating Tumor Extracellular Vesicles for Non-Invasive Monitoring of Metastatic Colorectal Cancer(EVA26) | not yet recruiting | — | 290 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 0 | Aug 10, 2026 | clinicaltrials |
| NCT07755917 | Preoperative Home-based Multimodal Prehabilitation Based on 5G + Artificial Intelligence Mobile Health | not yet recruiting | N/A | 490 | The Affiliated Hospital of Qingdao UniversityOTHER | 0 | Aug 10, 2026 | clinicaltrials |
| NCT07756281 | First in Human Study of SNV1521 With a RAS Inhibitor for People With Advanced Pancreatic Cancer | not yet recruiting | Phase 1 | 40 | Synnovation Therapeutics, Inc.INDUSTRY | 0 | Aug 10, 2026 | clinicaltrials |
| NCT07752875 | A Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation | not yet recruiting | Phase 1 / Phase 2 | 250 | LG ChemINDUSTRY | 0 | Aug 7, 2026 | clinicaltrials |
| NCT07101666 | Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer(TNT-SHORT) | not yet recruiting | Phase 2 | 20 | Washington University School of MedicineOTHER | 1 | Aug 6, 2026 | clinicaltrials |
| NCT07744139 | Radiogenomic Profiling of Dendritic Cells and Macrophages to Predict Recurrence in Colorectal Liver Metastasis(RaP-DMac-LiMe) | not yet recruiting | — | 210 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 0 | Aug 6, 2026 | clinicaltrials |
| NCT07748611 | SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial | not yet recruiting | Phase 2 | 125 | Northwestern UniversityOTHER | 1 | Aug 6, 2026 | clinicaltrials |
| NCT07749859 | SHR-1701 Plus Apatinib for Second-Line Treatment in Targeted-Immune Pretreated Advanced Hepatocellular Carcinoma | not yet recruiting | Phase 2 | 80 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Aug 6, 2026 | clinicaltrials |
| NCT07209215 | ctDNA-Informed Management of Early-Stage Rectal Cancer(ULTIMATE) | not yet recruiting | Phase 2 | 200 | University of California, DavisOTHER | 1 | Aug 5, 2026 | clinicaltrials |
| NCT07642492 | REcovery After Cancer Application(RECapp) | not yet recruiting | N/A | 250 | Karolinska InstitutetOTHER | 1 | Aug 5, 2026 | clinicaltrials |
| NCT07653594 | TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE) | not yet recruiting | N/A | 20 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 5, 2026 | clinicaltrials |
| NCT07746830 | Prospective Assessment of Alignment Between Multimodal Artificial Intelligence and Multidisciplinary Team Decisions in Gastrointestinal Oncology | not yet recruiting | — | 69 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Aug 5, 2026 | clinicaltrials |
| NCT07748481 | Comparison of the Therapeutic Efficacy of Non-touch Microwave Ablation, Tumor-puncture Microwave Ablation and Surgical Resection for Subcapsular Hepatocellular Carcinoma | not yet recruiting | — | 180 | The First Hospital of Jilin UniversityOTHER | 0 | Aug 5, 2026 | clinicaltrials |
| NCT07582003 | S-Adenosylmethionine (SAMe) for Chemoprevention of Colorectal Adenomas | not yet recruiting | Phase 1 | 18 | Jun Gong, MDOTHER | 1 | Aug 4, 2026 | clinicaltrials |
| NCT07689812 | A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.(SIGNAL-IO 301) | not yet recruiting | N/A | 920 | Natera, Inc.INDUSTRY | 0 | Aug 4, 2026 | clinicaltrials |
| NCT07737600 | A Study of MRG007 Combination Therapy for Advanced Colorectal Cancer | not yet recruiting | Phase 1 / Phase 2 | 316 | Lepu Biopharma Co., Ltd.INDUSTRY | 1 | Aug 4, 2026 | clinicaltrials |
| NCT07745023 | Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality Among Survivors of Breast, Prostate, Endometrial, or Colorectal Cancer | not yet recruiting | N/A | 30 | Roswell Park Cancer InstituteOTHER | 0 | Aug 4, 2026 | clinicaltrials |
| NCT07745296 | Investigating Precision Medicine in the Adjuvant Setting in Biliary Tract Cancer(SAFIR-IMPACT) | not yet recruiting | Phase 3 | 990 | UNICANCEROTHER | 0 | Aug 4, 2026 | clinicaltrials |
| NCT07745790 | Safety and Efficacy of Multimodal Thermal Therapy (MTT) Combined With KRAS G12V mRNA Vaccine, S-1, and Sintilimab in Patients With Metastatic Pancreatic Cancer | not yet recruiting | Phase 2 | 20 | Ruijin HospitalOTHER | 1 | Aug 4, 2026 | clinicaltrials |
| NCT07597252 | ctDNA Monitoring After Pancreatic Cancer Surgery (K-4CARE Lite Study)(K4CARE-PDAC) | not yet recruiting | — | 30 | Chang Gung Memorial HospitalOTHER | 1 | Aug 3, 2026 | clinicaltrials |
| NCT07741903 | Development of a Risk Prediction Model for Immune-Targeted Therapy-Related Diarrhea in Patients With Hepatocellular Carcinoma Based on TCM Constitutional Types: A Prospective Cohort Study | not yet recruiting | — | 500 | Affiliated Hospital of Chengde Medical UniversityOTHER | 0 | Aug 3, 2026 | clinicaltrials |
| NCT07738939 | IKS04 Regimen in Advanced Solid Tumors That Express CA242 | not yet recruiting | Phase 1 | 120 | Iksuda Therapeutics Ltd.INDUSTRY | 1 | Jul 31, 2026 | clinicaltrials |
| NCT07733817 | Impact of Probiotics on Neuropathy Induced by Adjuvant Chemotherapy in Patients With Colon Cancer.(PROBIOCOL) | not yet recruiting | N/A | 130 | Centre Francois BaclesseOTHER | 1 | Jul 30, 2026 | clinicaltrials |
| NCT07738042 | To Explore a Single-arm Phase II Study on Intestinal Microbiota Transplantation Combined With Neoadjuvant Immunotherapy and Chemoradiotherapy for Locally Advanced Rectal Cancer Under MSS/pMMR | not yet recruiting | N/A | 46 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jul 30, 2026 | clinicaltrials |
| NCT07509008 | Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum | not yet recruiting | Phase 1 / Phase 2 | 10 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07528430 | Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Pancreatic Cancer | not yet recruiting | — | 450 | University of Maryland, BaltimoreOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07732504 | AI-Guided Surveillance and Curative Salvage of Recurrence After Hepatocellular Carcinoma Resection or Ablation(HCC-AI-RECLAIM) | not yet recruiting | N/A | 2,000 | Tongji HospitalOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07732543 | Developing and Testing the Effectiveness of Smart Healthcare Assisted Individualized Symptom Management Education and Home-based Exercise on Frailty, Treatment-related Adverse Events and Quality of Life in Advanced Gastric Cancer Patients Receiving Immunotherapy | not yet recruiting | N/A | 110 | Taipei Veterans General Hospital, TaiwanOTHER_GOV | 0 | Jul 29, 2026 | clinicaltrials |
| NCT07732686 | Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry | not yet recruiting | — | 2,000 | University of OklahomaOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT07734857 | Peripheral Blood Biomarkers and Response to Atezolizumab Plus Bevacizumab in Hepatocellular Carcinoma | not yet recruiting | — | 100 | Shanghai Zhongshan HospitalOTHER | 0 | Jul 29, 2026 | clinicaltrials |
| NCT07735065 | Tumor-Specific T-Cells (cCTL:GL01) for Advanced Gastrointestinal Cancer(cCTL) | not yet recruiting | Phase 1 | 20 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 0 | Jul 29, 2026 | clinicaltrials |
| NCT07580339 | Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 30 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT07729917 | Precision Integrated Strategies and Efficacy Evaluation for Biliary Tract Cancers: An Umbrella Platform Study | not yet recruiting | Phase 2 | 240 | Zhejiang UniversityOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT06414122 | Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients(MOMENT) | not yet recruiting | N/A | 88 | University of CologneOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT07724951 | The Efficacy and Safety of Donafenib Plus PD-1/L1 Monoclonal Antibodies Plus TACE or HAIC as First-line Treatment for Unresectable Hepatocellular Carcinoma A Multi-center, Retrospective Clinical Study | not yet recruiting | — | 400 | Shanghai Zhongshan HospitalOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT07726212 | A First-in-human (FIH), Open-Label, Dose Escalation and Expansion Cohorts Study of MC002 | not yet recruiting | Phase 1 | 143 | Hangzhou MacroLink Biopharmaceutical LLCINDUSTRY | 0 | Jul 27, 2026 | clinicaltrials |
| NCT07726966 | Betacyanin for Early Diagnosis and Recovery of Anastomotic Leakage After Rectal Cancer Surgery: A Single-Center, Prospective, Controlled Trial | not yet recruiting | N/A | 120 | Southwest Hospital, ChinaOTHER | 1 | Jul 27, 2026 | clinicaltrials |
| NCT07729033 | A Phase II Exploratory Study of Sacituzumab Tirumotecan Combined With Envafolimab for TROP2-Positive Advanced Biliary Tract Cancers Previously Treated With First-Line Immunotherapy Combined With Chemotherapy. | not yet recruiting | Phase 2 | 28 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jul 27, 2026 | clinicaltrials |
Data updated 22 days agoSource updated Aug 14, 2026source: clinicaltrials