Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,101 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,000)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04104672 | A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies(ARC-8) | completed | Phase 1 | 196 | Arcus Biosciences, Inc.INDUSTRY | 1 | Sep 9, 2026 | clinicaltrials |
| NCT07409987 | TENS and Compression for Established Oxaliplatin-Induced Peripheral Neuropathy | completed | N/A | 140 | Cumhuriyet UniversityOTHER | 1 | Sep 9, 2026 | clinicaltrials |
| NCT04015765 | Hybrid-APC Margin Ablation to Prevent Post EMR Adenoma Recurrence(h-APC_EMR) | completed | N/A | 376 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Sep 8, 2026 | clinicaltrials |
| NCT01591733 | FOLFIRINOX + RT for Pancreatic Cancer | completed | Phase 2 | 48 | Massachusetts General HospitalOTHER | 1 | Sep 4, 2026 | clinicaltrials |
| NCT01972919 | MR Guided Phase II Radiotherapy Dose Escalation in Unresectable Non-Metastatic Pancreatic Cancer | completed | Phase 2 | 23 | Medical College of WisconsinOTHER | 1 | Sep 4, 2026 | clinicaltrials |
| NCT04427527 | Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia(ACCSIS) | completed | N/A | 29,772 | Mark Dignan, PhDOTHER | 1 | Sep 4, 2026 | clinicaltrials |
| NCT05281380 | VITAMin Insufficiency in Esophagogastric Neoplasms(VITAMIN) | completed | N/A | 107 | Zuyderland Medisch CentrumOTHER | 1 | Sep 4, 2026 | clinicaltrials |
| NCT06390059 | EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma | completed | Phase 2 | 84 | NovoCure Ltd.INDUSTRY | 4 | Sep 4, 2026 | clinicaltrials |
| NCT06790355 | ProSight: A Multi-centre Interventional Study Evaluating MCED in Asymptomatic Population | completed | N/A | 2,527 | Shanghai Weihe Medical Laboratory Co., Ltd.INDUSTRY | 1 | Sep 4, 2026 | clinicaltrials |
| NCT04493060 | Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer | completed | Phase 2 | 22 | Mayo ClinicOTHER | 1 | Sep 3, 2026 | clinicaltrials |
| NCT02794428 | Chemoprevention of Gastric Carcinogenesis | completed | Phase 2 | 91 | Vanderbilt-Ingram Cancer CenterOTHER | 2 | Sep 2, 2026 | clinicaltrials |
| NCT04276493 | Anti-HER2 Bispecific Antibody Zanidatamab (ZW25) Activity in Combination With Chemotherapy With/Without Tislelizumab | completed | Phase 1 / Phase 2 | 71 | BeiGeneINDUSTRY | 3 | Sep 2, 2026 | clinicaltrials |
| NCT05709197 | The Effectiveness of Adding Braun Anastomosis to Standard Child Reconstruction After Pancreatoduodenectomy(REMBRANDT) | completed | N/A | 256 | Radboud University Medical CenterOTHER | 1 | Sep 2, 2026 | clinicaltrials |
| NCT05721846 | Nivolumab With Ipilimumab Combined With TGFβ-15 Peptide Vaccine and Radiotherapy for Pancreatic Cancer(CheckVAC) | completed | Phase 1 | 20 | Inna Chen, MDOTHER | 1 | Sep 2, 2026 | clinicaltrials |
| NCT05864144 | A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 98 | Sensei Biotherapeutics, Inc.INDUSTRY | 1 | Sep 2, 2026 | clinicaltrials |
| NCT06495463 | Lonsurf® (Trifluridine/Tipiracil) Plus Chemotherapy in Metastatic Colorectal Cancer Prospective Study in Taiwan | completed | N/A | 97 | Chang Gung Memorial HospitalOTHER | 1 | Sep 2, 2026 | clinicaltrials |
| NCT02676349 | Neoadjuvant mFolfirinox With or Without Preoperative Concomitant Chemoradiotherapy in Patients With Borderline Resectable Pancreatic Carcinoma (PANDAS-PRODIGE 44) | completed | Phase 2 | 130 | Institut de Cancérologie de LorraineOTHER | 1 | Sep 1, 2026 | clinicaltrials |
| NCT02997553 | Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery(GASVERT) | completed | Phase 3 | 744 | Institut de Cancérologie de LorraineOTHER | 1 | Sep 1, 2026 | clinicaltrials |
| NCT04209686 | Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma | completed | Phase 2 | 19 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Sep 1, 2026 | clinicaltrials |
| NCT00469339 | Risk Communication Within Mexican-American Families | completed | — | 498 | National Human Genome Research Institute (NHGRI)NIH | 1 | Aug 31, 2026 | clinicaltrials |
| NCT05391321 | Identification of the Most Suitable Questionnaire to Assess the Sexual Function of Women Living in France After Colorectal Cancer Surgery(EVAS-CCR) | completed | N/A | 23 | University Hospital, LimogesOTHER | 1 | Aug 31, 2026 | clinicaltrials |
| NCT05772546 | Avatrombopag vs. Placebo for CIT in GI Malignancies(ACT-GI) | completed | Phase 2 | 49 | Hanny Al-Samkari, MDOTHER | 1 | Aug 31, 2026 | clinicaltrials |
| NCT06212817 | Dietary Fiber Before Colorectal Cancer Surgery | completed | N/A | 54 | Wageningen UniversityOTHER | 1 | Aug 31, 2026 | clinicaltrials |
| NCT06236321 | The Microbrect-FFC Study | completed | N/A | 15 | University of AberdeenOTHER | 1 | Aug 31, 2026 | clinicaltrials |
| NCT03366155 | Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver | completed | Phase 2 | 24 | National Cancer Institute (NCI)NIH | 1 | Aug 28, 2026 | clinicaltrials |
| NCT04787341 | PAnitumumab REchallenge Followed by REgorafenib Versus the Reverse Sequence(PARERE) | completed | Phase 2 | 213 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Aug 28, 2026 | clinicaltrials |
| NCT05328765 | A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection(ACTION HIV) | completed | — | 369 | Latin American Cooperative Oncology GroupOTHER | 5 | Aug 28, 2026 | clinicaltrials |
| NCT03674073 | A Study Combining Personalized Neoantigen-based Dendritic Cell Vaccine With Microwave Ablation for the Treatment of Hepatocellular Carcinoma | completed | Phase 1 | 24 | Chinese PLA General HospitalOTHER | 1 | Aug 27, 2026 | clinicaltrials |
| NCT04540211 | A Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma(SKYSCRAPER-08) | completed | Phase 3 | 461 | Hoffmann-La RocheINDUSTRY | 5 | Aug 27, 2026 | clinicaltrials |
| NCT05754229 | Accuracy of Real Time Characterization in Artificial Intelligence-assisted Colonoscopy | completed | N/A | 395 | Ismail GögenurOTHER | 1 | Aug 27, 2026 | clinicaltrials |
| NCT06737692 | Effects of Aerobic and Resistance Exercise Training in Individuals With Cancer Cachexia(Exercise) | completed | N/A | 40 | Dokuz Eylul UniversityOTHER | 1 | Aug 27, 2026 | clinicaltrials |
| NCT07763314 | Trends and Short-term Outcomes of Surgically Resected Early-onset Colorectal Cancer in Switzerland Between 2003 and 2022 | completed | — | 73,771 | Cantonal Hospital of St. GallenOTHER | 1 | Aug 27, 2026 | clinicaltrials |
| NCT07791329 | Sequential FDG-PET and miRNA as Biomarkers of Preoperative Treatment Strategy in LA Oesophago-Gastric Cancer(GastroPET) | completed | Phase 2 | 144 | Masaryk Memorial Cancer InstituteOTHER | 1 | Aug 27, 2026 | clinicaltrials |
| NCT00712751 | The Sexual Health of Rectal Cancer Patients | completed | — | 149 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 26, 2026 | clinicaltrials |
| NCT03615326 | Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811) | completed | Phase 3 | 738 | Merck Sharp & Dohme LLCINDUSTRY | 20 | Aug 26, 2026 | clinicaltrials |
| NCT05176860 | Evaluation of Novel Cone-Beam CT for Guidance and Adaptation of Precision Radiotherapy | completed | N/A | 31 | Varian, a Siemens Healthineers CompanyINDUSTRY | 1 | Aug 26, 2026 | clinicaltrials |
| NCT05589675 | Evaluation of a New Invitation Procedure to the French Organized Colorectal Cancer Screening Program(KITCOLO22) | completed | N/A | 71,117 | International Agency for Research on CancerOTHER | 1 | Aug 26, 2026 | clinicaltrials |
| NCT00217737 | Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer | completed | Phase 3 | 2,431 | National Cancer Institute (NCI)NIH | 5 | Aug 25, 2026 | clinicaltrials |
| NCT02206360 | Pancreatic Cancer Early Detection Program(PCEDP) | completed | — | 181 | White Plains HospitalOTHER | 1 | Aug 25, 2026 | clinicaltrials |
| NCT04039607 | A Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Hepatocellular Carcinoma(CheckMate 9DW) | completed | Phase 3 | 732 | Bristol-Myers SquibbINDUSTRY | 26 | Aug 25, 2026 | clinicaltrials |
| NCT04670445 | Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer(UPLIFT) | completed | N/A | 199 | Massachusetts General HospitalOTHER | 1 | Aug 25, 2026 | clinicaltrials |
| NCT05487248 | A Study of On-treatment ctDNA Changes in Chemo-refractory Colorectal Cancer Patients(COPERNIC) | completed | N/A | 103 | Jules Bordet InstituteOTHER | 2 | Aug 25, 2026 | clinicaltrials |
| NCT01882933 | D2 Resection and HIPEC (Hyperthermic Intraperitoneal Chemoperfusion) in Locally Advanced Gastric Carcinoma(GASTRICHIP) | completed | Phase 3 | 367 | Hospices Civils de LyonOTHER | 2 | Aug 24, 2026 | clinicaltrials |
| NCT03399110 | XELOX for 4 Months Versus 6 Months in Gastric Cancer (LOMAC) | completed | Phase 3 | 1,024 | Fudan UniversityOTHER | 1 | Aug 24, 2026 | clinicaltrials |
| NCT03902600 | A Study of Photon and Proton Chemoradiotherapy as Definitive or Neoadjuvant Therapy in Non-Metastatic Pancreatic Cancer | completed | — | 103 | Mayo ClinicOTHER | 1 | Aug 24, 2026 | clinicaltrials |
| NCT07549269 | Comparison of Nab-Paclitaxel Versus Paclitaxel in Neoadjuvant Immunochemotherapy Therapy for Esophageal Squamous Cell Carcinoma: A Retrospective IPTW-Adjusted Analysis | completed | — | 387 | Sichuan UniversityOTHER | 1 | Aug 24, 2026 | clinicaltrials |
| NCT07781319 | Early Gastric Cancer in the Spanish EURECCA Registry | completed | — | 600 | Corporacion Parc TauliOTHER | 0 | Aug 24, 2026 | clinicaltrials |
| NCT01918527 | Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer | completed | Phase 3 | 250 | Vejle HospitalOTHER | 3 | Aug 21, 2026 | clinicaltrials |
Data updated 21 days agoSource updated Sep 9, 2026source: clinicaltrials