Cancer Family
Malignant Digestive System Neoplasm
CI-CAN-00000229Explore in graph →
4,262 active trials43 approved drugs556 evidence items
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Cancer Family
CI-CAN-00000229Explore in graph →
Clinical trials
19,101 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (2,000)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06173466 | Postoperative Analgesia With Liposomal Bupivacaine Versus Standard Bupivacaine Combined With Dexamethasone | completed | Phase 4 | 96 | Zhejiang Cancer HospitalOTHER | 1 | Jun 26, 2025 | clinicaltrials |
| NCT07020468 | Neoadjuvant Therapy （NALIRIFOX） for Locally Advanced Colon and Upper Rectal Cancer(HOPE) | active not recruiting | Phase 4 | 57 | Affiliated Cancer Hospital of Shantou University Medical CollegeOTHER | 1 | Jun 13, 2025 |
| clinicaltrials |
| NCT06077487 | Ketamine-assisted Therapy for Advanced GI Cancer | terminated | Phase 4 | 1 | Brian Anderson, MDOTHER | 1 | May 21, 2025 | clinicaltrials |
| NCT06090994 | Prevention of Recurrence and Metastasis of Colorectal Cancer by Comparing Huaier With Capecitabine Monotherapy | recruiting | Phase 4 | 756 | Fudan UniversityOTHER | 1 | May 7, 2025 | clinicaltrials |
| NCT02047994 | Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality(GISTAR) | recruiting | Phase 4 | 30,000 | International Agency for Research on CancerOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT06935708 | Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery | recruiting | Phase 4 | 98 | Meri MircetaOTHER | 1 | Apr 20, 2025 | clinicaltrials |
| NCT06931808 | Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer | enrolling by invitation | Phase 4 | 20 | First Affiliated Hospital of Ningbo UniversityNETWORK | 1 | Apr 17, 2025 | clinicaltrials |
| NCT06923176 | Effect of Biejia-Ruangan Compound on Survival Rate and Recurrence Rate of Hepatocellular Carcinoma After Radical Treatment(BRCSRRRHCCART) | not yet recruiting | Phase 4 | 704 | Zhiyun YangOTHER | 0 | Apr 11, 2025 | clinicaltrials |
| NCT06779318 | Maintenance Chemotherapy With S-1 vs. Observation After Adjuvant Therapy for Resected Pancreatic Cancer With High Risk of Recurrence/Metastasis | not yet recruiting | Phase 4 | 464 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Apr 3, 2025 | clinicaltrials |
| NCT05551299 | Treatment of Non-resectable Bile Duct Cancer with Radiofrequency Ablation or Photodynamic Therapy(CARP) | recruiting | Phase 4 | 258 | University of LeipzigOTHER | 1 | Mar 27, 2025 | clinicaltrials |
| NCT06881563 | Intrathecal Morphine Versus Epidural Analgesia for Laparoscopic Colon Surgery | not yet recruiting | Phase 4 | 98 | Meri MircetaOTHER | 1 | Mar 18, 2025 | clinicaltrials |
| NCT04731558 | Pre- Vs Postoperative Thromboprophylaxis for Liver Resection(PREPOSTEROUS) | recruiting | Phase 4 | 1,012 | Helsinki University Central HospitalOTHER | 2 | Feb 14, 2025 | clinicaltrials |
| NCT05245877 | Pre- Vs. Postoperative Thromboprophylaxis in Pancreatic Surgery(PREPOSTEROUS2) | recruiting | Phase 4 | 800 | Helsinki University Central HospitalOTHER | 3 | Feb 14, 2025 | clinicaltrials |
| NCT06594744 | Endoscopic Variceal Ligation vs Carvedilol for the Prevention of First Esophageal Variceal Bleeding in Patients With HCC(P-HCC-CVL) | recruiting | Phase 4 | 120 | Taipei Veterans General Hospital, TaiwanOTHER_GOV | 1 | Feb 13, 2025 | clinicaltrials |
| NCT06818773 | Inetetamab Plus Chemotherapy ± PD-1/PD-L1 in HER2+ Advanced Biliary Cancer | not yet recruiting | Phase 4 | 35 | Eastern Hepatobiliary Surgery HospitalOTHER | 0 | Feb 10, 2025 | clinicaltrials |
| NCT02853500 | Effect of Surefire Infusion Device on Tumor Response to Regional Intra-arterial Therapy for Primary Liver Malignancies | withdrawn | Phase 4 | 0 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 5, 2025 | clinicaltrials |
| NCT03298945 | Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens | completed | Phase 4 | 2,239 | VA Office of Research and DevelopmentFED | 1 | Feb 5, 2025 | clinicaltrials |
| NCT01804166 | A Research Study to Bank Samples for Future Evaluation to Identify Biomarkers That Predispose Crohn's Disease and Ulcerative Colitis Patients to Develop Hepatosplenic T-Cell Lymphoma (HSTCL) | completed | Phase 4 | 1 | Janssen Scientific Affairs, LLCINDUSTRY | 1 | Feb 4, 2025 | clinicaltrials |
| NCT05848947 | SIR-Spheres Study to Calculate the Radiation-Absorbed Dose of 99mTc-MAA(MAApping) | completed | Phase 4 | 5 | Sirtex MedicalINDUSTRY | 1 | Jan 29, 2025 | clinicaltrials |
| NCT05717400 | Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-Acting Antiviral Therapy | terminated | Phase 4 | 2 | M.D. Anderson Cancer CenterOTHER | 1 | Dec 31, 2024 | clinicaltrials |
| NCT05894694 | Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer | recruiting | Phase 4 | 320 | Guang'anmen Hospital of China Academy of Chinese Medical SciencesOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT03564938 | Regorafenib in Indian Patients With Metastatic Colorectal Cancer (mCRC). | completed | Phase 4 | 100 | BayerINDUSTRY | 1 | Dec 3, 2024 | clinicaltrials |
| NCT03024684 | Statin for Preventing Hepatocellular Carcinoma Recurrence After Curative Treatment(SHOT) | active not recruiting | Phase 4 | 240 | Chiayi Christian HospitalOTHER | 1 | Nov 12, 2024 | clinicaltrials |
| NCT06665334 | To Explore the Effect of Huaier Granule on the Negative Conversion Rate After the CEA Level Increases Again After Colorectal Cancer Surgery | not yet recruiting | Phase 4 | 134 | Fudan UniversityOTHER | 0 | Oct 31, 2024 | clinicaltrials |
| NCT05784311 | Standard Versus Prolonged Antibiotic Prophylaxis After Pancreatoduodenectomy (SPARROW)(SPARROW) | recruiting | Phase 4 | 344 | Leiden University Medical CenterOTHER | 1 | Oct 21, 2024 | clinicaltrials |
| NCT06353126 | DEB-TACE Prior to Liver Transplantation in the Treatment of HCC | recruiting | Phase 4 | 40 | RenJi HospitalOTHER | 1 | Oct 18, 2024 | clinicaltrials |
| NCT05250648 | Clinical Trial on HIPEC With Mitomycin C in Colon Cancer Peritoneal Metastases (GECOP-MMC)(GECOP-MMC) | recruiting | Phase 4 | 216 | Hospital Universitario de FuenlabradaOTHER | 1 | Oct 9, 2024 | clinicaltrials |
| NCT06464380 | Anti-cancer Potentiality of Saffron Against Hepatocellular Carcinoma | not yet recruiting | Phase 4 | 40 | Ain Shams UniversityOTHER | 1 | Sep 23, 2024 | clinicaltrials |
| NCT06590844 | "cindilizumab + Bevacizumab + Coenzyme I for Injection" in Unresectable Hepatocellular Carcinoma | unknown | Phase 4 | 37 | Anhui Provincial HospitalOTHER_GOV | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06499610 | Clinical Study of Irinotecan Liposome Combination Therapy for Advanced Gastric Cancer | not yet recruiting | Phase 4 | 44 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Jul 12, 2024 | clinicaltrials |
| NCT06496815 | Donafenib Combined With Immunotherapy and Local Therapy for Unresectable Hepatocellular Carcinoma That Has Failed in Previous Therapy | not yet recruiting | Phase 4 | 32 | Tongji HospitalOTHER | 0 | Jul 11, 2024 | clinicaltrials |
| NCT05410535 | To Evaluate Efficacy of Ursodeoxycholic Acid (UDCA) for the Prevention of Gallstone Formation After Gasterectomy | completed | Phase 4 | 431 | Daewoong Pharmaceutical Co. LTD.INDUSTRY | 1 | Jun 28, 2024 | clinicaltrials |
| NCT05498766 | Effect and Safety of Huaier Granule Versus SOX Regimen in Gastric Cancer Patients | not yet recruiting | Phase 4 | 702 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jun 24, 2024 | clinicaltrials |
| NCT05518929 | Hypoxia During Gastroenterological Endoscope Procedures Sedated With Ciprofol In Overweight Or Obesity Patients(SpO2) | completed | Phase 4 | 1,090 | RenJi HospitalOTHER | 1 | Jun 7, 2024 | clinicaltrials |
| NCT06417606 | Lenvatinib and Adebrelimab Combined With GEMOX in the Perioperative Treatment of Potentially Resectable Intrahepatic Cholangiocarcinoma | unknown | Phase 4 | 20 | Zhiyong HuangOTHER | 1 | May 22, 2024 | clinicaltrials |
| NCT04562428 | The Safety and Efficacy Evaluation of XSLJZ in Advanced Hepatocellular Carcinoma Patients With Multiple Protein Kinase Inhibitor Therapy: A Randomized, Double-Blind, Controlled Trial | completed | Phase 4 | 10 | China Medical University HospitalOTHER | 1 | May 16, 2024 | clinicaltrials |
| NCT06398028 | The Preoperative Administration of ICG Improves Tumor Detection in Patients Undergoing Minimally Invasive Hepatic Resection Guided by Conventional Intraoperative Ultrasound. | recruiting | Phase 4 | 173 | Hospital Universitari Vall d'Hebron Research InstituteOTHER | 1 | May 3, 2024 | clinicaltrials |
| NCT05354856 | The Effect of Chemoradiotherapy on Gastric Perfusion in Patients With Gastric Cancer. | terminated | Phase 4 | 11 | Rigshospitalet, DenmarkOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06388135 | Serplulimab Combined With Nab-paclitaxel and Cisplatin in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma | not yet recruiting | Phase 4 | 80 | Yang Jianjun, PhDOTHER | 0 | Apr 29, 2024 | clinicaltrials |
| NCT05661357 | Disitamab Vedotin Combined With Fruquintinib for mCRC With HER2 Expression(HCCSC-C03) | unknown | Phase 4 | 51 | Zhongnan HospitalOTHER | 1 | Apr 17, 2024 | clinicaltrials |
| NCT06316908 | Permanent Celiac Plexus Block: Comparison of Pain Score in Unilateral and Bilateral Posterior Percutaneous Approach | completed | Phase 4 | 30 | Sindh Institute of Urology and TransplantationOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06311916 | Efficacy and Safety of Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model. | not yet recruiting | Phase 4 | 312 | Chen XiaopingOTHER | 0 | Mar 15, 2024 | clinicaltrials |
| NCT05124002 | Recombinant Human Adenovirus Type 5 Plus HAIC of FOLFOX for Intrahepatic Cholangiocarcinoma | unknown | Phase 4 | 66 | Beijing Tsinghua Chang Gung HospitalOTHER | 1 | Mar 4, 2024 | clinicaltrials |
| NCT06041425 | The Effects of Oxycodone Versus Sufentanil on Pain and Inflammatory Response After TACE | completed | Phase 4 | 40 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT06269445 | The Efficacy and Safety of Lcaritin Combined With Bevacizumab and FOLFIRI in Treatment of Liver Metastases From Colorectal Cancer | unknown | Phase 4 | 20 | Sir Run Run Shaw HospitalOTHER | 1 | Feb 21, 2024 | clinicaltrials |
| NCT06169410 | Ramucirumab Combined With Nab-paclitaxel, Lobaplatin, and S-1 in Neoadjuvant Transformation Therapy for Advanced Gastric Cancer | unknown | Phase 4 | 140 | Yang Jianjun, PhDOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT03700411 | Influence of Opioid Analgesia on Circulating Tumor Cells in Open Colorectal Cancer Surgery(POACC-1) | completed | Phase 4 | 125 | The Institute of Molecular and Translational Medicine, Czech RepublicOTHER | 1 | Dec 7, 2023 | clinicaltrials |
| NCT03700541 | Influence of Opioid Analgesia on Circulating Tumor Cells in Laparoscopic Colorectal Cancer Surgery(POACC-2) | completed | Phase 4 | 71 | The Institute of Molecular and Translational Medicine, Czech RepublicOTHER | 1 | Dec 7, 2023 | clinicaltrials |
| NCT01416077 | Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection | completed | Phase 4 | 64 | University Hospital, LinkoepingOTHER | 1 | Dec 4, 2023 | clinicaltrials |
Data updated 22 days agoSource updated Jun 26, 2025source: clinicaltrials