Cancer
Malignant Central Nervous System Neoplasm
CI-CAN-00001115Explore in graph →
Top-level822 active trials5 approved drugs103 evidence items
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Cancer
CI-CAN-00001115Explore in graph →
Clinical trials
2,864 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (419)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01642823 | Cancer Biology of Retinoblastoma | terminated | — | 8 | Stanford UniversityOTHER | 2 | Mar 6, 2017 | clinicaltrials |
| NCT00582608 | Tumor Detection Using Iodine-131-Labeled Monoclonal Antibody 8H9 | terminated | N/A | 12 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 1, 2017 | clinicaltrials |
| NCT00171938 |
| Open-label Trial of Imatinib Mesylate in Patients With Unresectable Recurrent Glioblastoma Multiforme Expressing PDGFR (Platelet Derived Growth Factor Receptors) |
| terminated |
| Phase 2 |
| 30 |
| NovartisINDUSTRY |
| 1 |
| Feb 24, 2017 |
| clinicaltrials |
| NCT01148966 | Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors | terminated | Phase 1 | 6 | University of WashingtonOTHER | 1 | Feb 15, 2017 | clinicaltrials |
| NCT02025231 | Image Guided Reirradiation of High-grade Glioma | terminated | Phase 1 / Phase 2 | 31 | Rigshospitalet, DenmarkOTHER | 2 | Feb 8, 2017 | clinicaltrials |
| NCT02113007 | Study of High-Dose Rituximab With Temozolomide as Treatment for Primary Central Nervous System (CNS) Lymphoma | terminated | Phase 2 | 2 | SCRI Development Innovations, LLCOTHER | 1 | Feb 7, 2017 | clinicaltrials |
| NCT01857752 | Phase II Study Temozolomide for Retinoblastoma Metastatic to the Central Nervous System for Patients From Guatemala | terminated | Phase 2 | 3 | Stanford UniversityOTHER | 1 | Jan 30, 2017 | clinicaltrials |
| NCT02394665 | Dose Escalated MRSI Guided Radiation Therapy in Glioblastoma | terminated | Phase 2 | 1 | University of MiamiOTHER | 1 | Jan 5, 2017 | clinicaltrials |
| NCT02841332 | Multimodal Imaging Analysis During Treatment With Bevacizumab in Patients With Recurrent Glioblastoma(IMAGLIO) | terminated | N/A | 6 | University Hospital, ToulouseOTHER | 1 | Dec 20, 2016 | clinicaltrials |
| NCT00473408 | The Effect of Radiotherapy and Temozolomide on the Tumor Vasculature and Stem Cells in Human High-grade Astrocytomas(Gliomstudien) | terminated | — | 1 | Haukeland University HospitalOTHER | 1 | Dec 6, 2016 | clinicaltrials |
| NCT02371031 | FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas | terminated | Phase 1 | 11 | Washington University School of MedicineOTHER | 1 | Nov 30, 2016 | clinicaltrials |
| NCT01113463 | TPI 287 in Patients With Recurrent Glioblastoma Multiforme | terminated | Phase 2 | 17 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 31, 2016 | clinicaltrials |
| NCT00574964 | Gliadel Wafers and Temodar in the Treatment of Glioblastoma Multiforme(Temodar) | terminated | Phase 2 | 50 | University of IowaOTHER | 1 | Oct 27, 2016 | clinicaltrials |
| NCT02047747 | A Phase II Study of Dacomitinib in Progressive Brain Metastases | terminated | Phase 2 | 4 | David Piccioni, M.D., Ph.DOTHER | 1 | Sep 22, 2016 | clinicaltrials |
| NCT02370563 | PET Imaging of Intracranial Cancers With 18F-FSPG | terminated | Phase 1 | 26 | Lantheus Biosciences Ltd.INDUSTRY | 1 | Sep 2, 2016 | clinicaltrials |
| NCT01105702 | Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma | terminated | Phase 2 | 28 | NYU Langone HealthOTHER | 1 | Aug 4, 2016 | clinicaltrials |
| NCT01989052 | Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma | terminated | Phase 1 | 9 | Annick DesjardinsOTHER | 1 | Aug 4, 2016 | clinicaltrials |
| NCT01393769 | Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular Stage | terminated | Phase 2 | 5 | Hospital Sant Joan de DeuOTHER | 1 | Aug 2, 2016 | clinicaltrials |
| NCT01163539 | Cyberknife Radiosurgery and Quality of Life | terminated | — | 15 | Stanford UniversityOTHER | 1 | Jul 1, 2016 | clinicaltrials |
| NCT02060955 | Randomized Phase 2 Study to Investigate Efficacy of ALECSAT in Patients With GBM Measured Compared to Avastin/Irinotecan | terminated | Phase 2 | 25 | CytoVac A/SINDUSTRY | 1 | Jun 6, 2016 | clinicaltrials |
| NCT02031965 | Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery | terminated | Phase 1 | 2 | Pediatric Brain Tumor ConsortiumNETWORK | 1 | May 30, 2016 | clinicaltrials |
| NCT01499251 | Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma | terminated | Phase 1 | 75 | ActelionINDUSTRY | 1 | May 5, 2016 | clinicaltrials |
| NCT01351519 | A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors | terminated | Phase 2 | 16 | MultiCare Health System Research InstituteOTHER | 1 | Mar 17, 2016 | clinicaltrials |
| NCT01756729 | Post-approval Study of NovoTTF-100A in Recurrent GBM Patients | terminated | Phase 4 | 13 | NovoCure Ltd.INDUSTRY | 1 | Mar 2, 2016 | clinicaltrials |
| NCT01954030 | Phase 1/2 CTO + Bevacizumab for Recurrent Glioma Post-Bevacizumab Failure | terminated | Phase 1 | 17 | Annick DesjardinsOTHER | 1 | Feb 19, 2016 | clinicaltrials |
| NCT01189240 | RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma | terminated | Phase 1 / Phase 2 | 13 | National Cancer Institute (NCI)NIH | 1 | Dec 14, 2015 | clinicaltrials |
| NCT01260467 | Memantine for Recurrent Glioblastoma | terminated | Phase 2 | 4 | University of RochesterOTHER | 1 | Dec 10, 2015 | clinicaltrials |
| NCT01778530 | TRC105 for Recurrent Glioblastoma | terminated | Phase 2 | 2 | National Cancer Institute (NCI)NIH | 1 | Oct 7, 2015 | clinicaltrials |
| NCT00923117 | Sunitinib to Treat Recurrent Brain Cancer | terminated | Phase 2 | 87 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2015 | clinicaltrials |
| NCT01898273 | Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma | terminated | Phase 2 | 7 | Cellectar Biosciences, Inc.INDUSTRY | 1 | Sep 9, 2015 | clinicaltrials |
| NCT01558960 | Intravitreal Injections of Melphalan for Retinoblastoma | terminated | N/A | 10 | Hadassah Medical OrganizationOTHER | 1 | Aug 20, 2015 | clinicaltrials |
| NCT01227434 | A Study of PD 0332991 in Patients With Recurrent Rb Positive Glioblastoma(PD0332991) | terminated | Phase 2 | 23 | University of California, San FranciscoOTHER | 1 | Jul 17, 2015 | clinicaltrials |
| NCT01122888 | Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme | terminated | Phase 1 | 41 | National Cancer Institute (NCI)NIH | 1 | Apr 28, 2015 | clinicaltrials |
| NCT01100658 | Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors | terminated | N/A | 1 | University of MinnesotaOTHER | 1 | Mar 27, 2015 | clinicaltrials |
| NCT00432445 | Proton Beam Radiation Therapy for Intraocular and Periocular Retinoblastoma | terminated | Phase 2 | 2 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 27, 2015 | clinicaltrials |
| NCT02128373 | A Computer-Based Intervention for Distance Caregivers of Parents With Advanced Cancer | terminated | N/A | 7 | Case Comprehensive Cancer CenterOTHER | 1 | Feb 18, 2015 | clinicaltrials |
| NCT01378481 | High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma | terminated | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Dec 23, 2014 | clinicaltrials |
| NCT00761280 | Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma(SAPPHIRE) | terminated | Phase 3 | 27 | Isarna Therapeutics GmbHINDUSTRY | 16 | Nov 14, 2014 | clinicaltrials |
| NCT01088763 | Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia | terminated | Phase 1 | 129 | National Cancer Institute (NCI)NIH | 2 | Nov 5, 2014 | clinicaltrials |
| NCT00589095 | Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities | terminated | — | 5 | Yale UniversityOTHER | 1 | Jul 2, 2014 | clinicaltrials |
| NCT00387426 | Sunitinib in Treating Patients With Idiopathic Myelofibrosis | terminated | Phase 2 | 14 | National Cancer Institute (NCI)NIH | 1 | May 28, 2014 | clinicaltrials |
| NCT01515085 | MRI-Guided Laser Induced Thermal Therapy(LITT) | terminated | — | 1 | Rutgers, The State University of New JerseyOTHER | 1 | May 22, 2014 | clinicaltrials |
| NCT01403285 | Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma | terminated | Phase 1 | 6 | Immatics Biotechnologies GmbHINDUSTRY | 1 | May 19, 2014 | clinicaltrials |
| NCT00636805 | Aloxi for Prevention of Chemotherapy Induced Nausea and Vomiting in Malignant Glioma Patients Receiving Irinotecan With Bevacizumab | terminated | Phase 2 | 63 | Duke UniversityOTHER | 1 | Apr 1, 2014 | clinicaltrials |
| NCT01400958 | Nuvigil or Placebo in Newly Diagnosed Malignant Glioma | terminated | Phase 2 | 6 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 16, 2013 | clinicaltrials |
| NCT00003292 | S9624 Ifosfamide in Treating Patients With Meningeal Tumors | terminated | Phase 2 | 7 | SWOG Cancer Research NetworkNETWORK | 4 | Nov 8, 2013 | clinicaltrials |
| NCT01652768 | PRESENCE Project: An Early Palliative Care Intervention in Brain Tumors | terminated | N/A | 1 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 29, 2013 | clinicaltrials |
| NCT01205334 | Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme(COGLI) | terminated | Phase 1 / Phase 2 | 2 | Baylor College of MedicineOTHER | 1 | Aug 26, 2013 | clinicaltrials |
| NCT01095094 | Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma | terminated | Phase 2 | 19 | Case Comprehensive Cancer CenterOTHER | 1 | Jun 10, 2013 | clinicaltrials |
| NCT00005812 | Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma | terminated | Phase 2 | 12 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | May 14, 2013 | clinicaltrials |
Data updated 22 days agoSource updated Mar 6, 2017source: clinicaltrials