Subtype
Malignant Anorectal Neoplasm
CI-CAN-00005864Explore in graph →
452 active trials1 approved drugs6 evidence items
- NCIt
- C215225
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Subtype
CI-CAN-00005864Explore in graph →
Clinical trials
1,783 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (174)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02928692 | Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium(MAPOCD) | unknown | Phase 3 | 750 | RenJi HospitalOTHER | 1 | Jan 28, 2020 | clinicaltrials |
| NCT02736942 | COLOR III Trial: Transanal vs Laparoscopic TME(COLORIII) | unknown | Phase 3 | 1,104 | Amsterdam UMC, location VUmcOTHER | 1 | Jun 6, 2019 | clinicaltrials |
| NCT03975049 | Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer | not yet recruiting | Phase 3 | 933 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Jun 5, 2019 | clinicaltrials |
| NCT03671252 | Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation | recruiting | Phase 3 | 776 | Sun Yat-sen UniversityOTHER | 1 | Jan 23, 2019 | clinicaltrials |
| NCT00068692 | Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer | completed | Phase 3 | 225 | National Cancer Institute (NCI)NIH | 1 | Dec 4, 2018 | clinicaltrials |
| NCT01651949 | Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) | completed | Phase 3 | 2,520 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Nov 27, 2018 | clinicaltrials |
| NCT00254436 | A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly Procrit Given to Gastric or Rectal Patients | terminated | Phase 3 | 50 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 25, 2018 | clinicaltrials |
| NCT02127645 | Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer(NERATEM) | completed | Phase 3 | 25 | European Association for Endoscopic SurgeryOTHER | 1 | Jul 26, 2018 | clinicaltrials |
| NCT02907385 | Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing | unknown | Phase 3 | 736 | LifeBond Ltd.INDUSTRY | 7 | Mar 30, 2018 | clinicaltrials |
| NCT03431428 | Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients | unknown | Phase 3 | 477 | Zhang RuiOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT02163187 | Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation | terminated | Phase 2 / Phase 3 | 4 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2018 | clinicaltrials |
| NCT00911170 | PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study | completed | Phase 3 | 847 | AmgenINDUSTRY | 17 | Dec 29, 2017 | clinicaltrials |
| NCT02369939 | Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy(HYCAN) | unknown | Phase 3 | 118 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 11, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT00509444 | Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial(CPTD) | completed | Phase 3 | 200 | Johns Hopkins Bloomberg School of Public HealthOTHER | 1 | Apr 20, 2017 | clinicaltrials |
| NCT03038217 | Investigation of the Value of ctDNA in Diagnosis, Treatment, and Surveillance of Surgically Resectable Colorectal Cancer | unknown | Phase 3 | 300 | Peking Union Medical College HospitalOTHER | 0 | Feb 3, 2017 | clinicaltrials |
| NCT01786694 | Feasibility of Microdialysis by Laparoscopy(MTM-COLON-I) | completed | Phase 3 | 11 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Feb 1, 2017 | clinicaltrials |
| NCT00003596 | Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer | completed | Phase 3 | 682 | Radiation Therapy Oncology GroupNETWORK | 2 | Jan 4, 2017 | clinicaltrials |
| NCT02266849 | Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study | terminated | Phase 3 | 12 | Odense University HospitalOTHER | 1 | Oct 11, 2016 | clinicaltrials |
| NCT01372007 | Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma | completed | Phase 3 | 24 | University Hospital, GhentOTHER | 1 | Oct 7, 2016 | clinicaltrials |
| NCT02905968 | Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | unknown | Phase 2 / Phase 3 | 520 | Fudan UniversityOTHER | 1 | Sep 19, 2016 | clinicaltrials |
| NCT02770911 | Laparoscopic Anterior Resection With or Without "Dog Ear" Double-stapled Anastomosis for Rectal Cancer | unknown | Phase 3 | 250 | Fujian Medical UniversityOTHER | 0 | May 12, 2016 | clinicaltrials |
| NCT00075868 | Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer | completed | Phase 3 | 233 | Radiation Therapy Oncology GroupNETWORK | 1 | Nov 17, 2015 | clinicaltrials |
| NCT01211210 | Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal Cancer(FOWARC) | unknown | Phase 2 / Phase 3 | 495 | Sun Yat-sen UniversityOTHER | 1 | May 22, 2015 | clinicaltrials |
| NCT01814969 | Preoperative Hyperfractionated Radiotherapy or Radiochemotherapy in Locally Advanced Rectal Cancer. | unknown | Phase 3 | 260 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | May 5, 2015 | clinicaltrials |
| NCT00782457 | Prospective Randomised Study Comparing Laparoscopic Versus Open Surgery in Patients With Rectal Cancer | completed | Phase 3 | 200 | Hospital Universitario Virgen de la ArrixacaOTHER | 0 | Mar 18, 2015 | clinicaltrials |
| NCT01423214 | A Trial to Assess Robot-assisted Surgery and Laparoscopy-assisted Surgery in Patients With Mid or Low Rectal Cancer(COLRAR) | unknown | Phase 3 | 540 | Kyungpook National University HospitalOTHER | 1 | Mar 11, 2015 | clinicaltrials |
| NCT01941979 | A Study Comparing Adjuvant Chemotherapy Versus Observation for Patients With Rectal Adenocarcinoma After Neoadjuvant Chemo-Radiotherapy Treatment. | unknown | Phase 3 | 309 | Instituto do Cancer do Estado de São PauloOTHER | 1 | Oct 30, 2014 | clinicaltrials |
| NCT00499369 | Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy | terminated | Phase 3 | 72 | National Cancer Institute (NCI)NIH | 1 | Jul 31, 2014 | clinicaltrials |
| NCT00025090 | Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer | completed | Phase 3 | 600 | University College London (UCL) Cancer InstituteOTHER | 1 | Aug 26, 2013 | clinicaltrials |
| NCT00145769 | A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum | completed | Phase 3 | 326 | Trans Tasman Radiation Oncology GroupOTHER | 2 | Aug 9, 2013 | clinicaltrials |
| NCT01861678 | Randomized Controlled Trial to Evaluate High Tie Versus Low Tie of the Inferior Mesenteric Artery in Anterior Resection | unknown | Phase 3 | 331 | Shoichi Fujii, MD, PhDOTHER | 1 | Aug 6, 2013 | clinicaltrials |
| NCT01872104 | Safety and Efficiency of Photodynamic Therapy for Rectal Cancer(PDT-R-01) | suspended | Phase 2 / Phase 3 | 100 | li xiongOTHER | 1 | Jun 7, 2013 | clinicaltrials |
| NCT00005036 | Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer | completed | Phase 3 | 560 | National Cancer Institute (NCI)NIH | 1 | May 3, 2013 | clinicaltrials |
| NCT00005094 | Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps | completed | Phase 3 | 1,170 | National Cancer Institute (NCI)NIH | 1 | Apr 12, 2013 | clinicaltrials |
| NCT00070122 | Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Colorectal Cancer | terminated | Phase 3 | 2,200 | National Cancer Institute (NCI)NIH | 1 | Jan 25, 2013 | clinicaltrials |
| NCT00003873 | Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer | completed | Phase 3 | 950 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00025337 | Combination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With Advanced or Metastatic Colorectal Cancer That Has Been Previously Treated | completed | Phase 3 | 880 | National Cancer Institute (NCI)NIH | 1 | Jan 24, 2013 | clinicaltrials |
| NCT00601549 | A Randomized Controlled Clinical Trial Comparing Oncological Results and Functional Recovery Between Laparoscopic and Open Method for the Treatment of Advanced Rectal Cancer After Concurrent Chemoradiation Therapy (CCRT) | unknown | Phase 3 | 600 | National Taiwan University HospitalOTHER | 1 | Dec 6, 2012 | clinicaltrials |
| NCT00068744 | Radiation Therapy, Mitomycin, and Either Fluorouracil or Cisplatin in Treating Patients With Locally Advanced Anal Cancer | terminated | Phase 2 / Phase 3 | 88 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 7 | Sep 24, 2012 | clinicaltrials |
| NCT00470951 | Randomized Prospective Trial for Laparoscopic vs Open Resection for Rectal Cancer(CTS-179) | unknown | Phase 3 | 340 | National Cancer Center, KoreaOTHER_GOV | 1 | Aug 17, 2012 | clinicaltrials |
| NCT01653301 | Preoperative Downstaging of Extraperitoneal T3 Rectal Cancer: XELOXRT Versus XELACRT. A Multicenter, Phase III Study(INTERACT) | unknown | Phase 3 | 616 | Catholic University of the Sacred HeartOTHER | 1 | Jul 31, 2012 | clinicaltrials |
| NCT01609504 | ELRR by TEM Versus Laparoscopic TME in iT2N0M0 SMALL LOW RECTAL CANCER(ELRRvsLTME) | completed | Phase 3 | 283 | University of Roma La SapienzaOTHER | 0 | Jun 1, 2012 | clinicaltrials |
| NCT01579591 | VSL#3 Versus Placebo in Increasing the Pathological Major Response Rate in Patients With Rectal Cancer | unknown | Phase 3 | 160 | Catholic University of the Sacred HeartOTHER | 1 | Apr 18, 2012 | clinicaltrials |
| NCT01064999 | A Trial of High Intensity Versus Low Intensity Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer | unknown | Phase 2 / Phase 3 | 240 | Fudan UniversityOTHER | 1 | Mar 14, 2012 | clinicaltrials |
| NCT01459328 | Resource-Sparing Curative Treatment for Rectal Cancer | unknown | Phase 3 | 350 | International Atomic Energy AgencyOTHER_GOV | 11 | Oct 25, 2011 | clinicaltrials |
| NCT00606983 | Prevention of Acute Voiding Difficulty After Radical Proctectomy | completed | Phase 3 | 100 | Seoul National University HospitalOTHER | 1 | Jul 20, 2011 | clinicaltrials |
| NCT00230646 | Promoting Physical Activity After Colorectal Cancer | completed | Phase 3 | 46 | The Miriam HospitalOTHER | 1 | Oct 5, 2010 | clinicaltrials |
| NCT01186081 | Comparison of Preoperative and Postoperative Radiotherapy and Capecitabine in Locally Advanced Rectal Cancer | completed | Phase 3 | 240 | Asan Medical CenterOTHER | 1 | Aug 23, 2010 | clinicaltrials |
| NCT01130233 | Randomized Trial on Robotic Assisted Resection for Rectal Cancer | unknown | Phase 3 | 98 | The University of Hong KongOTHER | 1 | May 25, 2010 | clinicaltrials |
Data updated 22 days agoSource updated Jan 28, 2020source: clinicaltrials