Clinical trial · Interventional
Feasibility of Microdialysis by Laparoscopy
NCT01786694CI-TRIAL-00025748MTM-COLON-IcompletedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this pilot study is to evaluate the feasibility of microdialysis by laparoscopy in order to identify anastomotic leaks after rectal surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cma microdialysis catheter placement | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- cma microdialysis catheter placement
- description
- At the end of the surgery the cma microdialysis catheter is placed near the anastomosis
- interventionNames
- Device: cma microdialysis catheter placement
Primary outcomes (1)
- measure
- functional success of microdialysis
- timeFrame
- postoperative day 5
- description
- the functional success of microdialysis is defined as abnormal values localised at the microdialysis catheter
Secondary outcomes (4)
- measure
- anastomotic leaks rate
- timeFrame
- postoperative day 30
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * rectal disease requiring proctectomy with anastomosis and stomy * proctectomy by laparoscopy * written consent Exclusion Criteria: * history of colorectal surgery * rectal surgery without anastomosis * breastfeeding or pregnancy * ASA score IV
References
Publications (3)
- BACKGROUNDHogberg N, Carlsson PO, Hillered L, Meurling S, Stenback A. Intestinal ischemia measured by intraluminal microdialysis. Scand J Clin Lab Invest. 2012 Feb;72(1):59-66. doi: 10.3109/00365513.2011.629307. Epub 2011 Nov 21. PMID 22103734
- BACKGROUNDDeeba S, Corcoles EP, Hanna GB, Pareskevas P, Aziz O, Boutelle MG, Darzi A. Use of rapid sampling microdialysis for intraoperative monitoring of bowel ischemia. Dis Colon Rectum. 2008 Sep;51(9):1408-13. doi: 10.1007/s10350-008-9375-4. Epub 2008 May 24. PMID 18500500
- BACKGROUNDVerdant CL, Chierego M, De Moor V, Chamlou R, Creteur J, de Dieu Mutijima J, Loi P, Gelin M, Gullo A, Vincent JL, De Backer D. Prediction of postoperative complications after urgent laparotomy by intraperitoneal microdialysis: A pilot study. Ann Surg. 2006 Dec;244(6):994-1002. doi: 10.1097/01.sla.0000225092.45734.e6. PMID 17122625