Clinical trial · Interventional
Safety and Efficiency of Photodynamic Therapy for Rectal Cancer
Longterm Outcome of Photodynamic Therapy Compared With Chemotherapy Alone in Patients With Advanced Rectal Cancer
NCT01872104CI-TRIAL-00010658PDT-R-01suspendedPhase 2 / Phase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Modifying the clinnicaltrials
Summary
Brief summary (as posted)
This research is a prospective randomized controlled trial.It aimed to determine longterm outcomes and factors associated with increased survival after photodynamic therapy (PDT) through colonscopy compared with chemotherapy alone in patients presenting with advanced rectal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Rectal Cancer | Malignant Rectal Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Photodynamic therapy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Chemotherapy alone
- description
- Group that be scheduled to undergo chemothrapy only using FOLFOX4 protocol.
- type
- EXPERIMENTAL
- label
- PDT and Chemotherapy
- description
- Group that not only be scheduled to undergo chemothrapy using FOLFOX4 protocol,but also receive colonscopy-assisted PDT.
- interventionNames
- Procedure: Photodynamic therapy
Primary outcomes (1)
- measure
- Survival rate
- timeFrame
- one month
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 25 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * 1.Patients with advanced rectal cancer 2.Patients are willing to join in this clinical trial. Exclusion Criteria: * 1.Patients with advanced rectal cancer can not suffer PDT procedure. 2.Allergy to photosensitizer
References
Publications (1)
- RESULTAllison RR, Sheng C, Cuenca R, Bagnato VS, Austerlitz C, Sibata CH. Photodynamic therapy for anal cancer. Photodiagnosis Photodyn Ther. 2010 Jun;7(2):115-9. doi: 10.1016/j.pdpdt.2010.04.002. Epub 2010 May 7. PMID 20510306