- NCIt
- C3512
- OncoTree
- LUAD
- DOID
- 3910
- UMLS CUI
- C0152013
- MeSH
- D000077192
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Genomics
20 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
915 cases with simple somatic mutation data · 915 cases total · 2026-04-07 · mapped to Lung Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 485 |
| 915 |
| 53% |
| cbioportal |
| 2 | EGFR | Ssm | 268 | 915 | 29.3% | cbioportal |
| 3 | KRAS | Ssm | 241 | 915 | 26.3% | cbioportal |
| 4 | STK11 | Ssm | 157 | 915 | 17.2% | cbioportal |
| 5 | KEAP1 | Ssm | 153 | 915 | 16.7% | cbioportal |
| 6 | SMARCA4 | Ssm | 92 | 915 | 10.1% | cbioportal |
| 7 | PTPRD | Ssm | 89 | 915 | 9.7% | cbioportal |
| 8 | RBM10 | Ssm | 78 | 915 | 8.5% | cbioportal |
| 9 | FAT1 | Ssm | 71 | 915 | 7.8% | cbioportal |
| 10 | ARID1A | Ssm | 69 | 915 | 7.5% | cbioportal |
| 11 | NF1 | Ssm | 67 | 915 | 7.3% | cbioportal |
| 12 | PTPRT | Ssm | 67 | 915 | 7.3% | cbioportal |
| 13 | ATM | Ssm | 65 | 915 | 7.1% | cbioportal |
| 14 | PIK3CA | Ssm | 65 | 915 | 7.1% | cbioportal |
| 15 | EPHA3 | Ssm | 59 | 915 | 6.4% | cbioportal |
| 16 | KMT2D | Ssm | 58 | 915 | 6.3% | cbioportal |
| 17 | HGF | Ssm | 56 | 915 | 6.1% | cbioportal |
| 18 | SETD2 | Ssm | 56 | 915 | 6.1% | cbioportal |
| 19 | KMT2C | Ssm | 53 | 915 | 5.8% | cbioportal |
| 20 | ATRX | Ssm | 52 | 915 | 5.7% | cbioportal |
| 23 | RB1 | Ssm | 50 | 915 | 5.5% | cbioportal |
| 21 | BRAF | Ssm | 50 | 915 | 5.5% | cbioportal |
| 22 | EPHA5 | Ssm | 50 | 915 | 5.5% | cbioportal |
| 42 | ZFHX3 | Ssm | 34 | 623 | 5.5% | cbioportal |
| 24 | APC | Ssm | 49 | 915 | 5.4% | cbioportal |
| 25 | CDKN2A | Ssm | 49 | 915 | 5.4% | cbioportal |
| 50 | EPHA7 | Ssm | 31 | 623 | 5% | cbioportal |
| 26 | ARID2 | Ssm | 45 | 915 | 4.9% | cbioportal |
| 27 | NTRK3 | Ssm | 44 | 915 | 4.8% | cbioportal |
| 55 | MGA | Ssm | 29 | 623 | 4.7% | cbioportal |
Data updated 22 days agoSource updated 2026-04-07