Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,846 active trials21 approved drugs383 evidence items
- NCIt
- C215201
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,846 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06919510 | A Phase ll Study of Neoadjuvant Short-course Radiotherapy Followed by Ivonescimab and Chemotherapy in pMMR/MSS Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 90 | Sun Yat-sen UniversityOTHER | 0 | Apr 9, 2025 | clinicaltrials |
| NCT04062721 | Local Immunomodulation After Radiofrequency of Unresectable Colorectal Liver Metastases(LICoRN-01) | not yet recruiting | Phase 1 | 12 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Apr 6, 2025 |
| clinicaltrials |
| NCT06901856 | Endoscopic Resection for Small Rectal Neuroendocrine Tumors | not yet recruiting | N/A | 120 | Guangdong Provincial People's HospitalOTHER | 0 | Mar 30, 2025 | clinicaltrials |
| NCT06899477 | Pre-Operative Treatment in REseCTable COlon CanceR | not yet recruiting | Phase 3 | 714 | Dominik Paul ModestOTHER | 1 | Mar 28, 2025 | clinicaltrials |
| NCT06887673 | Lipid Mediators & Cancer: Montelukast, SPM, and Almonds | not yet recruiting | Early Phase 1 | 56 | University of South FloridaOTHER | 1 | Mar 20, 2025 | clinicaltrials |
| NCT06881563 | Intrathecal Morphine Versus Epidural Analgesia for Laparoscopic Colon Surgery | not yet recruiting | Phase 4 | 98 | Meri MircetaOTHER | 1 | Mar 18, 2025 | clinicaltrials |
| NCT06790212 | Neoadjuvant CAPOX Plus Ivonescimab Versus CAPOX for Locally Advanced Colon Cancer | not yet recruiting | Phase 2 | 168 | Sun Yat-sen UniversityOTHER | 0 | Mar 17, 2025 | clinicaltrials |
| NCT06879873 | MRD-Guided Surveillance in Operable Colon Adenocarcinoma (I-III)(SURVEILLANCE-I)(SURI) | not yet recruiting | — | 390 | Fudan UniversityOTHER | 0 | Mar 17, 2025 | clinicaltrials |
| NCT06879886 | MRD-Guided Surveillance in Resectable Stage IV Metastatic Colorectal Cancer (SURVEILLANCE-II)(SURII) | not yet recruiting | — | 181 | Fudan UniversityOTHER | 0 | Mar 17, 2025 | clinicaltrials |
| NCT06879899 | MRD-Guided Surveillance in Locally Advanced Mid-Low Rectal Cancer (SURVEILLANCE-III)(SURIII) | not yet recruiting | — | 139 | Fudan UniversityOTHER | 0 | Mar 17, 2025 | clinicaltrials |
| NCT06872606 | Short-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal Cancer(SCRIPBOT) | not yet recruiting | Phase 2 | 33 | Sir Run Run Shaw HospitalOTHER | 1 | Mar 12, 2025 | clinicaltrials |
| NCT06863038 | Predictive Value of PREMM5, MMRpredict, and Universal Tumor Screening for Lynch Syndrome in Vietnam(Predict_LS_VN) | not yet recruiting | — | 572 | University of Medicine and Pharmacy at Ho Chi Minh CityOTHER | 1 | Mar 7, 2025 | clinicaltrials |
| NCT06860685 | Trial of Gum Chewing to Enhance the Restoration of Intestinal Motility in Colorectal Cancer Surgery | not yet recruiting | Phase 1 / Phase 2 | 292 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Mar 6, 2025 | clinicaltrials |
| NCT05636085 | Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced Adenoma(reconAAsense) | not yet recruiting | — | 15,000 | Mainz BiomedINDUSTRY | 0 | Mar 5, 2025 | clinicaltrials |
| NCT06858956 | Real-World Study of Chidamide Combined With PD-(L)1 Inhibitors and Anti-Angiogenic Therapy for Advanced MSS-Type Colorectal Cancer | not yet recruiting | — | 200 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 0 | Mar 5, 2025 | clinicaltrials |
| NCT06858969 | Chidamide in Combination With PD-1 Inhibitor, Bevacizumab, and XELOX for Metastatic Colorectal Cancer | not yet recruiting | Phase 2 | 130 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 0 | Mar 5, 2025 | clinicaltrials |
| NCT06838546 | A Multicenter, Open Phase IIb Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Colorectal Cancer | not yet recruiting | Phase 2 | 80 | Tasly Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | Feb 20, 2025 | clinicaltrials |
| NCT06105203 | RATME Vs LATME in Middle and Low Rectal Cancer | not yet recruiting | N/A | 1,026 | The First Hospital of Jilin UniversityOTHER | 1 | Feb 19, 2025 | clinicaltrials |
| NCT06835179 | SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer. | not yet recruiting | Phase 2 | 28 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 0 | Feb 19, 2025 | clinicaltrials |
| NCT06823323 | The Study on the Efficacy and Safety of Lactobacillus Johnsonii in Combination with CapeOX and Pembrolizumab for the Treatment of MSS/pMMR Metastatic Colorectal Cancer.(MSSpMMRCapeOX) | not yet recruiting | N/A | 150 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Feb 12, 2025 | clinicaltrials |
| NCT06791616 | Surveillance Intervals After Piecemeal Resection of Non-pedunculated Colorectal Lesions ≥20mm | not yet recruiting | N/A | 746 | Asociación Española de GastroenterologíaOTHER | 0 | Jan 24, 2025 | clinicaltrials |
| NCT06792292 | Artificial Intelligence-Assisted Colonoscopy in Colorectal Cancer Screening in a General Hospital(Delta-AI) | not yet recruiting | N/A | 765 | ChirecOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT06787807 | Proteomic Analysis of Patients Undergoing Bariatric Surgery | not yet recruiting | N/A | 103 | Universidade Federal de PernambucoOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06783153 | Efficacy and Safety of Adjunctive Use of Rifaximin In Preventing Radiotherapy-induced Diarrhea in Cancer Patients | not yet recruiting | Phase 1 / Phase 2 | 80 | Mansoura UniversityOTHER | 1 | Jan 20, 2025 | clinicaltrials |
| NCT06776120 | Fecal Immunochemical Test in Diagnosing Colorectal Cancer Among Vietnamese Patients with Lower Gastrointestinal Symptoms | not yet recruiting | N/A | 1,575 | Luu Ngoc MaiOTHER | 1 | Jan 15, 2025 | clinicaltrials |
| NCT06760520 | Short-course Radiotherapy Followed by CAPOX and Ivonescimab for Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 40 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 0 | Jan 8, 2025 | clinicaltrials |
| NCT06738225 | Serum MicroRNAs as Diagnostic Biomarkers of Colorectal Cancer | not yet recruiting | — | 80 | Bishoy ShehataOTHER | 0 | Dec 27, 2024 | clinicaltrials |
| NCT06751394 | Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal Cancer(TRACER) | not yet recruiting | Phase 2 | 44 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT06746298 | A Prospective Study of Expression Profiling-based Assessment of the Efficacy of Neoadjuvant Therapy for Rectal Cancer | not yet recruiting | — | 118 | Shanghai Minimally Invasive Surgery CenterOTHER | 0 | Dec 24, 2024 | clinicaltrials |
| NCT06746545 | A Prospective, Open-label, Single-arm Phase II Clinical Study of Fruquintinib Combined With S-1 for the Treatment of Metastatic Colorectal Cancer. | not yet recruiting | Phase 2 | 30 | Fujian Cancer HospitalOTHER_GOV | 0 | Dec 24, 2024 | clinicaltrials |
| NCT06745700 | Impact of Behavioral Activation on Depression and Quality of Life in Patients with Colon Cancer(BAdepCa) | not yet recruiting | N/A | 400 | Region VästmanlandOTHER | 1 | Dec 20, 2024 | clinicaltrials |
| NCT06724263 | A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid Tumors | not yet recruiting | Phase 2 | 120 | Tasly Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | Dec 9, 2024 | clinicaltrials |
| NCT06710561 | The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Injectable SPN01 in Phase I. | not yet recruiting | Phase 1 | 32 | Beijing SonoPhotoNano Medical Technology Co., Ltd.OTHER | 0 | Dec 3, 2024 | clinicaltrials |
| NCT06711939 | Vocorder Device Validation in Clinical Settings - Continuous Monitoring of Individuals (Vocorder Clinical Validation-VCV)(VCV) | not yet recruiting | — | 515 | Mitera HospitalOTHER | 1 | Dec 2, 2024 | clinicaltrials |
| NCT06710639 | Effects of Cognitive Training on Chemotherapy-Induced Cognitive Impairment in Colon Cancer Patients Undergoing Treatment(Chemobrain) in Oncology Patients With Colon Cancer Undergoing Active Treatment | not yet recruiting | N/A | 50 | University of SalamancaOTHER | 0 | Nov 29, 2024 | clinicaltrials |
| NCT06700317 | Intraoperative Hyperspectral Imaging for Laparoscopic Surgery(LapHSI) | not yet recruiting | N/A | 40 | King's College LondonOTHER | 0 | Nov 21, 2024 | clinicaltrials |
| NCT06690606 | EOCRCPred: an AI Model to Predict Survival in EOCRC Patients After Surgery | not yet recruiting | — | 250 | Shanghai University of Traditional Chinese MedicineOTHER | 1 | Nov 15, 2024 | clinicaltrials |
| NCT06688110 | Evaluation of Gixam's Efficacy Predicting Pre-cancerous Colorectal Polyps and Colorectal Cancer | not yet recruiting | N/A | 800 | Jubaan Ltd.INDUSTRY | 1 | Nov 14, 2024 | clinicaltrials |
| NCT06652529 | Phase 1 Dose Escalation and Expansion to Evaluate AROG4-01 in Patients With Advanced Solid Tumors(AROG4-01-01) | not yet recruiting | Phase 1 | 35 | Aromics TherapeuticsINDUSTRY | 0 | Nov 7, 2024 | clinicaltrials |
| NCT06669923 | Understanding Sugar-Sweetened Beverages (SSB) and Colorectal Cancer (CRC)(SSB and CRC) | not yet recruiting | N/A | 120 | University of VirginiaOTHER | 0 | Nov 1, 2024 | clinicaltrials |
| NCT06665334 | To Explore the Effect of Huaier Granule on the Negative Conversion Rate After the CEA Level Increases Again After Colorectal Cancer Surgery | not yet recruiting | Phase 4 | 134 | Fudan UniversityOTHER | 0 | Oct 31, 2024 | clinicaltrials |
| NCT06665087 | CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC | not yet recruiting | Phase 2 | 110 | Fudan UniversityOTHER | 0 | Oct 30, 2024 | clinicaltrials |
| NCT06666166 | SHR-A1811 Combined with Apatinib in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer | not yet recruiting | Phase 2 | 28 | Yunpeng LiuOTHER | 1 | Oct 30, 2024 | clinicaltrials |
| NCT06652412 | CGA Guided Ultrafractionated RT and Systemic Treatment in Elderly or Frail Patients with Inoperable Localized CRC | not yet recruiting | Phase 2 | 124 | Fudan UniversityOTHER | 0 | Oct 28, 2024 | clinicaltrials |
| NCT06645301 | BGT007 Treatment for Recurrent/refractory Gastrointestinal Malignancies | not yet recruiting | Early Phase 1 | 15 | BioSyngen Pte LtdINDUSTRY | 0 | Oct 16, 2024 | clinicaltrials |
| NCT06619743 | HPV Infection and Vaginal Microecology in Immunosuppressed Women | not yet recruiting | — | 10,000 | Lan ZhuOTHER | 0 | Oct 1, 2024 | clinicaltrials |
| NCT06619886 | TP53 R248Q TCR-T Cell Therapy for Advanced Solid Tumor | not yet recruiting | Early Phase 1 | 9 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Oct 1, 2024 | clinicaltrials |
| NCT06614751 | A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway | not yet recruiting | Phase 1 | 112 | Danatlas Pharmaceuticals Co., LtdINDUSTRY | 1 | Sep 27, 2024 | clinicaltrials |
| NCT06616259 | First-line Treatment of MCapOX + Cetuximab Vs. MFOLFOX6 + Cetuximab for RAS/BRAF Wild-type, MSS, Unresectable Left-Sided MCRC: a Multicenter, Randomized, Controlled, Phase III Study(CAPCET-III) | not yet recruiting | Phase 3 | 452 | Meng QiuOTHER | 1 | Sep 27, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Apr 9, 2025source: clinicaltrials