Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07504263 | Phase 1/2a Study of RP-001 in Participants With Advanced Malignancies | not yet recruiting | Phase 1 / Phase 2 | 66 | Recurv Pharma IncINDUSTRY | 0 | Mar 31, 2026 | clinicaltrials |
| NCT07502014 | A Clinical Study of Iparomlimab and Tuvonralimab Combined With Fruquintinib and Heterogeneous Radiotherapy Versus Fruquintinib as Third-Line and Subsequent-Line Treatment for Metastatic Colorectal Cancer | not yet recruiting | Phase 2 | 60 | Huazhong University of Science and TechnologyOTHER | 0 | Mar 30, 2026 |
| clinicaltrials |
| NCT07489833 | Metabolomic Pathways and Traditional Chinese Medicine Body Constitution in Cancer-related Fatigue | not yet recruiting | — | 80 | Chang Gung Memorial HospitalOTHER | 0 | Mar 27, 2026 | clinicaltrials |
| NCT07089771 | Virtual Versus Dye-based Chromoendoscopy in Inflammatory Bowel Disease Surveillance Colonoscopy | not yet recruiting | N/A | 480 | Region StockholmOTHER_GOV | 1 | Mar 20, 2026 | clinicaltrials |
| NCT07486180 | The Application of a Novel Endoluminal Robotic System for Colorectal Endoscopic Submucosal Dissection | not yet recruiting | N/A | 10 | Chinese University of Hong KongOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT07483060 | Next Generation STAR-TREC (NG-ST) - Organ Preservation in Early Rectal Cancer(NG-ST) | not yet recruiting | Phase 4 | 90 | Vastra Gotaland RegionOTHER_GOV | 0 | Mar 19, 2026 | clinicaltrials |
| NCT07472868 | Neoadjuvant FOLFOXIRI and Chemoradiotherapy Versus Neoadjuvant CAPOX/FOLFOX and Chemoradiotherapy Followed by Surgery or a Watch-and-Wait Approach in High Risk Locally Advanced Rectal Cancer(MEND-IT II) | not yet recruiting | Phase 3 | 394 | J. W. A. BurgerOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT07474025 | Integrating Peritoneal Histological Growth Patterns Into Preoperative Decision-Making for Colorectal Peritoneal Metastses | not yet recruiting | — | 30 | Jules Bordet InstituteOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT07469306 | Short-Course RT Plus CAPOX and Tislelizumab vs Long-Course CRT Plus Tislelizumab for Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 130 | Fujian Cancer HospitalOTHER_GOV | 1 | Mar 13, 2026 | clinicaltrials |
| NCT07467590 | Combination of High and Low-Dose Radiotherapy With Immune Therapy and TKI in Advanced Colorectal Cancer: A Phase II Study(TRIUNITE-07) | not yet recruiting | Phase 2 | 33 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 0 | Mar 12, 2026 | clinicaltrials |
| NCT07463690 | Construction and Evaluation of a Flipped Discharge Model for Stomates With Colorectal Cancer | not yet recruiting | N/A | 200 | Sun Yat-sen UniversityOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT07453797 | A Prospective Study Assessing ActivSight Imaging for Intraoperative Perfusion Evaluation in Left-Sided Colectomy(VISION) | not yet recruiting | N/A | 150 | Activ SurgicalINDUSTRY | 0 | Mar 6, 2026 | clinicaltrials |
| NCT07453173 | ONCO-RET: Supervised Resistance Training During Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer(ONCO-RET) | not yet recruiting | N/A | 15 | Fundacion Arturo Lopez PerezOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT07446465 | FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion Therapy for Initially Unresectable pMMR/MSS Colorectal Cancer | not yet recruiting | Phase 4 | 42 | Ye XuOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT07435584 | Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE)(EVER-RECODE) | not yet recruiting | Phase 1 / Phase 2 | 38 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Feb 27, 2026 | clinicaltrials |
| NCT07409844 | Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer(RESET C2) | not yet recruiting | Phase 2 | 152 | Ismail GögenurOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT07420010 | An Open-label, Single-arm Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of KT032 Cell Injection in Patients With Mesothelin-positive Advanced Solid Tumors. | not yet recruiting | Early Phase 1 | 24 | Weijia Fang, MDOTHER | 0 | Feb 19, 2026 | clinicaltrials |
| NCT07410767 | Advanced Endoscopic Resections for Rectal Neoplasms | not yet recruiting | — | 300 | Jagiellonian UniversityOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT07361575 | Study Comparing the Quality of Colon Cleanliness With Prepackaged LRD (Low-residue Diet) vs. Guided (POG).(POG) | not yet recruiting | N/A | 230 | Clinique Paris-BercyOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07411781 | PIN in Combination With Sintilimab in Previously Treated pMMR/MSS CRC With Hepatic Metastases | not yet recruiting | Phase 1 | 25 | Chinese PLA General HospitalOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07413146 | Neoadjuvant CAPEOX Versus Upfront Surgery for Locally Advanced Colon Cancer With Elevated CEA: A Single-Center, Open-Label, Randomized Controlled Trial | not yet recruiting | N/A | 100 | Sun Yat-sen UniversityOTHER | 0 | Feb 17, 2026 | clinicaltrials |
| NCT07414082 | Serum Talin-1 and Cripto-1 in Colorectal Cancer(Talin-1/CR-1) | not yet recruiting | N/A | 70 | Assiut UniversityOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07410546 | Quantitative Fecal Immunochemical Test for Detection of Colorectal Cancer and Precancerous Lesions in Sohag | not yet recruiting | — | 150 | Sohag UniversityOTHER | 0 | Feb 13, 2026 | clinicaltrials |
| NCT07398456 | Smartphone-enabled Hybrid Identification of Early CoLorectal Disease Using Blood-Based Cancer Testing Across TeXas(SHIELD-TX) | not yet recruiting | N/A | 5,500 | Baylor Research InstituteOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT07405736 | Lubiprostone Combined With Maintenance Therapy for Prevention of Postoperative Recurrence in Peritoneal Metastatic Colorectal Cancer | not yet recruiting | Phase 2 | 124 | Sun Yat-sen UniversityOTHER | 0 | Feb 12, 2026 | clinicaltrials |
| NCT07406958 | Advanced Classification of Colon Tumors From CT Scans Using Deep Learning for Optimized Treatment Decision-making.(DeepColScan) | not yet recruiting | — | 1,000 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT07397442 | Short-Course Radiotherapy Combined With Chemotherapy and Immunotherapy in Mid-Low Locally Advanced Rectal Cancer | not yet recruiting | Phase 2 | 19 | Beijing Friendship HospitalOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT07402486 | A Phase II Prospective Study of Maastro Applicator Brachytherapy for Rectal Cancer | not yet recruiting | Phase 2 | 20 | Siriraj HospitalOTHER | 0 | Feb 11, 2026 | clinicaltrials |
| NCT07403877 | Neoadjuvant Immunotherapy ± Radiotherapy in MSI-H/dMMR Locally Advanced Colorectal Cancer(TORCH-OPTIMA) | not yet recruiting | Phase 2 | 114 | Fudan UniversityOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT07395063 | A Clinical Study on the Treatment of Metastatic Colorectal Cancer at the Second-line or Beyond. | not yet recruiting | Phase 2 | 68 | The Fourth Affiliated Hospital of Zhejiang University School of MedicineOTHER | 0 | Feb 9, 2026 | clinicaltrials |
| NCT07386431 | The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma | not yet recruiting | — | 30 | University Medical Centre LjubljanaOTHER | 0 | Feb 6, 2026 | clinicaltrials |
| NCT07391566 | LPM6690176 in Combination With Chemotherapy and Bevacizumab in Metastatic Colorectal Cancer Patients With RAS Mutation | not yet recruiting | Phase 1 / Phase 2 | 99 | Luye Pharma Group Ltd.INDUSTRY | 1 | Feb 6, 2026 | clinicaltrials |
| NCT07394192 | Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer(PKUCH- R11) | not yet recruiting | Phase 2 | 44 | Peking University Cancer Hospital & InstituteOTHER | 0 | Feb 6, 2026 | clinicaltrials |
| NCT07376668 | Effects of a WhatsApp-assisted Prehabilitation for Patient Undergoing Elective Colorectal Cancer Surgery | not yet recruiting | N/A | 100 | Tseung Kwan O Hospital, Hong KongOTHER | 1 | Feb 3, 2026 | clinicaltrials |
| NCT07381400 | Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study) | not yet recruiting | Phase 2 | 128 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 0 | Feb 3, 2026 | clinicaltrials |
| NCT07382635 | Clinical Trial Protocol for Evaluating the Efficacy and Safety of Thoracoabdominal Endoscopic Surgery System in Remote Laparoscopic Surgery for Urology, General Surgery, Gynecology and Thoracic Surgery | not yet recruiting | — | 98 | Cornerstone RoboticsINDUSTRY | 0 | Feb 3, 2026 | clinicaltrials |
| NCT07384377 | JSKN003 Versus Physician Choiced Treatment in Patients With HER2-positive and Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-Fu, and Irinotecan | not yet recruiting | Phase 3 | 123 | Shanghai JMT-Bio Inc.INDUSTRY | 0 | Feb 3, 2026 | clinicaltrials |
| NCT02448173 | A Multicenter Study of Active Specific Immunotherapy With OncoVax® in Patients With Stage II Colon Cancer | not yet recruiting | Phase 3 | 550 | Vaccinogen IncINDUSTRY | 1 | Feb 2, 2026 | clinicaltrials |
| NCT07381777 | XELOX Plus DoSTARlimab Versus XELOX Alone as Consolidation Treatment After Standard Chemoradiation in pMMR/MSS or MSI-Low Locally Advanced Rectal Cancer (LARC) Patients(IMMUNOSTAR) | not yet recruiting | Phase 2 | 270 | Gruppo Oncologico Italiano di Ricerca ClinicaOTHER | 1 | Feb 2, 2026 | clinicaltrials |
| NCT07373015 | Modified Double Snare Assisted EMR (mDS-EMR) VS ESD for Rectal Neuroendocrine Tumors Smaller Than 1cm | not yet recruiting | N/A | 118 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 0 | Jan 28, 2026 | clinicaltrials |
| NCT07366554 | Epigenetic Factors of Colorectal Adenoma in Korean | not yet recruiting | — | 32 | Bundang CHA HospitalOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT07366047 | Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer | not yet recruiting | N/A | 40 | Peking University Cancer Hospital & InstituteOTHER | 0 | Jan 26, 2026 | clinicaltrials |
| NCT06811454 | Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET) | not yet recruiting | N/A | 76 | Case Comprehensive Cancer CenterOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT07362836 | Fruquintinib Versus Bevacizumab Plus Chemotherapy in Second-Line RAS-Mutant Metastatic Colorectal Cancer (FRU-RAS) | not yet recruiting | Phase 3 | 224 | Fudan UniversityOTHER | 0 | Jan 23, 2026 | clinicaltrials |
| NCT07363863 | Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma | not yet recruiting | — | 100 | Sohag UniversityOTHER | 0 | Jan 23, 2026 | clinicaltrials |
| NCT07364656 | Analysis of the Presence and Cardiac Functional Effects of Anti-NaV1.5 Autoantibodies in Patients With Metastatic Tumors | not yet recruiting | N/A | 196 | IRCCS Policlinico S. DonatoOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT07358585 | A Phase Ib/II Study to Evaluate HLX43 Combined With HLX07 or Serplulimab in Patients With Advanced or Metastatic Colorectal Cancer | not yet recruiting | Phase 1 / Phase 2 | 126 | Shanghai Henlius BiotechINDUSTRY | 1 | Jan 22, 2026 | clinicaltrials |
| NCT07358884 | First in Human Study of QLS5316 in Solid Tumors | not yet recruiting | Phase 1 | 300 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 0 | Jan 22, 2026 | clinicaltrials |
| NCT07361016 | Comparison of Laparoscopic and Open Total Mesocolic Excision With Central Vascular Ligation for Right Colon Carcinoma | not yet recruiting | N/A | 22 | Kafrelsheikh UniversityOTHER | 1 | Jan 22, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Mar 31, 2026source: clinicaltrials