Clinical trial · Observational
The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma. The study will include patients for whom surgical treatment of bowel endometriosis is clinically indicated. This research would represent a significant advancement in evaluating the necessity of surgical intervention in asymptomatic patients or those with mild symptoms. Furthermore, it would provide a broader insight into the systemic impact of endometriosis on other organ systems, ultimately improving risk assessment and preventive measures.
Conditions
Conditions (10)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bowel Endometriosis | — | UNRESOLVED | — |
| Carcinogenesis | — | UNRESOLVED | — |
| Colon Resection | — | UNRESOLVED | — |
| Colorectal Carcinoma | Colorectal Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Deep Endometriosis | — | UNRESOLVED | — |
| Endometriosis | — | UNRESOLVED | — |
| Endometriosis Pelvic | — | UNRESOLVED | — |
| Endometriosis Rectum | — | UNRESOLVED | — |
| Genetic Change | — | UNRESOLVED | — |
| Infertility | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Comparison of gene expression in healthy and with endometriosis affected bowel.
- timeFrame
- 3 years
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Female patients aged 18 and over, treated at the Department of Reproduction for diagnosed deep endometriosis, including bowel endometriosis, for whom surgical treatment is indicated. Exclusion Criteria: * Patients with known inflammatory bowel disease (IBD), patients with a personal history of gynecological or gastrointestinal malignancy
References
Publications (0)
Data not yet available