Clinical trial · Observational
Advanced Endoscopic Resections for Rectal Neoplasms
Adoption of Advanced Endoscopic Resection Methods in the Treatment of Rectal Neoplasms
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study evaluates how advanced endoscopic resection techniques affect treatment outcomes in adults with rectal cancer. Rectal cancer has traditionally been treated with standard abdominal surgery. Newer endoscopic techniques allow removal of selected early tumors and may reduce treatment-related complications. However, their effectiveness and safety in tumors with deeper invasion are not yet fully established. This multicenter retrospective observational study uses existing medical records from adults who underwent endoscopic or surgical resection of rectal tumors between 2015 and 2025. Researchers will analyze anonymized information on procedures performed and treatment outcomes to assess the safety and effectiveness of advanced endoscopic approaches. The results of this study may help guide treatment selection and improve care for people with rectal cancer.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Adenocarcinoma | Rectal Adenocarcinoma | ONTOLOGY_EXACT | 0.98 |
| Rectal Adenoma | Rectal Adenoma | ONTOLOGY_EXACT | 0.98 |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
| Rectal Neuroendocrine Neoplasm | Rectal Neuroendocrine Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Recurrent Rectal Adenocarcinoma | Rectal Adenocarcinoma | CURATED_BROADER | 0.78 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic intramuscular dissection | Procedure | — | UNRESOLVED |
| Endoscopic submucosal dissection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- ESD
- description
- Patients who underwent endoscopic submucosal dissection for rectal neoplasm
- interventionNames
- Procedure: Endoscopic submucosal dissection
- label
- EID
- description
- Patients who underwent endoscopic intermuscular dissection for rectal neoplasm
- interventionNames
- Procedure: Endoscopic intramuscular dissection
Primary outcomes (7)
- measure
- Major intraprocedural bleeding rate
- timeFrame
- During the procedure
- description
- Bleeding occurring during the procedure that required advanced endoscopic hemostatic interventions beyond standard coagulation with the tip of the knife of coagulation forceps, resulted in hemodynamic instability, caused a significant prolongation of the procedure over 15 minutes (based on video), or led to procedure interruption or conversion
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with rectal neoplasms treated by advanced endoscopic resection Exclusion Criteria: * hybrid resection performed * full-thickness resection performed * essential procedural or outcome data were unavailable
References
Publications (0)
Data not yet available