Histology
Invasive Carcinoma
CI-CAN-00001040Explore in graph →
603 active trials9 approved drugs37 evidence items
- NCIt
- C9480
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Histology
CI-CAN-00001040Explore in graph →
Genomics
65 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
379 cases with simple somatic mutation data · 379 cases total · 2026-01-05 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 113 |
| 379 |
| 29.8% |
| cbioportal |
| 2 | TTN | Ssm | 82 | 379 | 21.6% | cbioportal |
| 3 | PIK3CA | Ssm | 76 | 379 | 20.1% | cbioportal |
| 4 | CDH1 | Ssm | 55 | 379 | 14.5% | cbioportal |
| 5 | IGDCC4 | Ssm | 50 | 379 | 13.2% | cbioportal |
| 6 | ESR1 | Ssm | 43 | 379 | 11.3% | cbioportal |
| 7 | MUC16 | Ssm | 43 | 379 | 11.3% | cbioportal |
| 8 | HMCN1 | Ssm | 38 | 379 | 10% | cbioportal |
| 9 | ZKSCAN1 | Ssm | 37 | 379 | 9.8% | cbioportal |
| 10 | GIMAP6 | Ssm | 36 | 379 | 9.5% | cbioportal |
| 11 | SYNE1 | Ssm | 32 | 379 | 8.4% | cbioportal |
| 12 | RYR2 | Ssm | 31 | 379 | 8.2% | cbioportal |
| 13 | GATA3 | Ssm | 30 | 379 | 7.9% | cbioportal |
| 14 | RYR1 | Ssm | 29 | 379 | 7.7% | cbioportal |
| 15 | ZNF208 | Ssm | 28 | 379 | 7.4% | cbioportal |
| 17 | KMT2C | Ssm | 27 | 379 | 7.1% | cbioportal |
| 18 | OBSCN | Ssm | 27 | 379 | 7.1% | cbioportal |
| 16 | CSMD3 | Ssm | 27 | 379 | 7.1% | cbioportal |
| 19 | PTEN | Ssm | 24 | 379 | 6.3% | cbioportal |
| 20 | ANK2 | Ssm | 23 | 379 | 6.1% | cbioportal |
| 23 | RGPD4 | Ssm | 23 | 379 | 6.1% | cbioportal |
| 22 | LPIN1 | Ssm | 23 | 379 | 6.1% | cbioportal |
| 21 | DNAH5 | Ssm | 23 | 379 | 6.1% | cbioportal |
| 24 | SPTBN4 | Ssm | 23 | 379 | 6.1% | cbioportal |
| 30 | ZNF195 | Ssm | 22 | 379 | 5.8% | cbioportal |
| 25 | ABCA13 | Ssm | 22 | 379 | 5.8% | cbioportal |
| 28 | LCN9 | Ssm | 22 | 379 | 5.8% | cbioportal |
| 26 | ANO6 | Ssm | 22 | 379 | 5.8% | cbioportal |
| 27 | CHD9 | Ssm | 22 | 379 | 5.8% | cbioportal |
| 29 | PKD1 | Ssm | 22 | 379 | 5.8% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05