Subtype
Intracranial Neoplasm
CI-CAN-00001030Explore in graph →
Non-malignant521 active trials34 evidence items
- NCIt
- C4953
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Subtype
CI-CAN-00001030Explore in graph →
Clinical trials
2,177 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04525014 | RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors(PIRATE) | terminated | Phase 1 | 2 | EpicentRx, Inc.INDUSTRY | 1 | Oct 31, 2024 | clinicaltrials |
| NCT01246869 | Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water | terminated | Phase 1 | 2 | University of UtahOTHER | 1 | Oct 1, 2024 |
| clinicaltrials |
| NCT03539731 | [18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers | terminated | Phase 1 | 27 | Guido A. Davidzon, MD, SMOTHER | 1 | Aug 12, 2024 | clinicaltrials |
| NCT01483820 | Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma | terminated | Phase 1 / Phase 2 | 8 | Giselle ShollerOTHER | 1 | Aug 6, 2024 | clinicaltrials |
| NCT03189381 | Pilot Phase 2 Study Whole Brain Radiation Therapy With Simultaneous Integrated Boost for Patients With Brain Metastases | terminated | N/A | 20 | Indiana UniversityOTHER | 1 | Jun 28, 2024 | clinicaltrials |
| NCT02621515 | Nivo/Ipi Combination Therapy in Symptomatic Brain Metastases(CA209-322) | terminated | Phase 2 | 7 | University Medical Center GroningenOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT02624388 | Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)(UVA-Gen001) | terminated | Phase 2 | 4 | University of VirginiaOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT05518942 | Effects of SMR Neurofeedback on Insomnia in Patients With Benign Brain Tumors | terminated | N/A | 5 | Taipei Medical UniversityOTHER | 1 | Apr 22, 2024 | clinicaltrials |
| NCT04610684 | Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases | terminated | Phase 2 | 3 | Jeffrey ClarkeOTHER | 1 | Mar 13, 2024 | clinicaltrials |
| NCT03705351 | Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM | terminated | Phase 1 | 7 | Providence Health & ServicesOTHER | 1 | Mar 4, 2024 | clinicaltrials |
| NCT03403361 | Dual-Energy CT on Plan Quality, Dose-delivery Accuracy, and Simulated Outcomes of Patients Treated With Proton or Photon Therapy | terminated | N/A | 36 | Washington University School of MedicineOTHER | 1 | Mar 1, 2024 | clinicaltrials |
| NCT04341311 | Phase I Study of Marizomib + Panobinostat for Children With DIPG(DIPG) | terminated | Phase 1 | 4 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 15, 2024 | clinicaltrials |
| NCT02768337 | Cambridge Brain Mets Trial 1(CamBMT1) | terminated | Phase 1 / Phase 2 | 26 | Cambridge University Hospitals NHS Foundation TrustOTHER | 1 | Jan 31, 2024 | clinicaltrials |
| NCT01894633 | Study of Whole-brain Irradiation With Chloroquine for Brain Metastases(CLQ) | terminated | Phase 2 | 73 | Instituto Nacional de Cancerologia de MexicoOTHER | 1 | Jan 24, 2024 | clinicaltrials |
| NCT03451123 | FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors | terminated | Early Phase 1 | 1 | University of Alabama at BirminghamOTHER | 1 | Dec 19, 2023 | clinicaltrials |
| NCT04040400 | Study of Intraoperative Radiotherapy for Patients With Large Brain Metastases Treated With Neurosurgical Resection | terminated | N/A | 5 | University of LouisvilleOTHER | 1 | Oct 12, 2023 | clinicaltrials |
| NCT03190967 | T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery | terminated | Phase 1 / Phase 2 | 12 | National Cancer Institute (NCI)NIH | 1 | Oct 11, 2023 | clinicaltrials |
| NCT04167618 | 177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma | terminated | Phase 1 / Phase 2 | 2 | Y-mAbs TherapeuticsINDUSTRY | 5 | Oct 6, 2023 | clinicaltrials |
| NCT03430947 | Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain Metastases(RadioCoBRIM) | terminated | Phase 2 | 20 | Technische Universität DresdenOTHER | 1 | Sep 14, 2023 | clinicaltrials |
| NCT00659126 | Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors | terminated | Phase 2 | 40 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 7, 2023 | clinicaltrials |
| NCT04644315 | A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors(ALpha-T) | terminated | Phase 2 | 1 | Hoffmann-La RocheINDUSTRY | 1 | Aug 7, 2023 | clinicaltrials |
| NCT02774291 | Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes | terminated | Early Phase 1 | 3 | Albert Einstein College of MedicineOTHER | 1 | Aug 4, 2023 | clinicaltrials |
| NCT04422639 | Preoperative SRS/SRT vs Postoperative SRS/SRT for Brain Metastases | terminated | N/A | 3 | University of ArkansasOTHER | 1 | Jul 28, 2023 | clinicaltrials |
| NCT03515603 | Endocrine Outcome of Surgery for Pituitary Adenoma | terminated | N/A | 36 | University of UlmOTHER | 1 | May 17, 2023 | clinicaltrials |
| NCT03488472 | Radiosurgery Plus NovoTTF-200A for Metastatic Small Cell Lung Cancer to the Brain(RAD 1704) | terminated | N/A | 1 | Drexell Hunter BoggsOTHER | 1 | May 6, 2023 | clinicaltrials |
| NCT05590273 | Forgotten Voices: Addressing Unmet Needs in Brain Tumor Caregivers(AIM 2) | terminated | N/A | 1 | Virginia Commonwealth UniversityOTHER | 1 | May 3, 2023 | clinicaltrials |
| NCT03089749 | Characterization of Human Autoantibody Titers After Central Nervous System Insult(CHAT CNS) | terminated | — | 63 | University of UtahOTHER | 1 | Apr 14, 2023 | clinicaltrials |
| NCT03436433 | Seizure Prophylaxis in Patients With Glioma or Brain Metastasis | terminated | Phase 2 | 4 | Duke UniversityOTHER | 1 | Apr 13, 2023 | clinicaltrials |
| NCT04730349 | A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer(PIVOT IO 020) | terminated | Phase 1 / Phase 2 | 15 | Bristol-Myers SquibbINDUSTRY | 6 | Mar 24, 2023 | clinicaltrials |
| NCT02490878 | Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases | terminated | Phase 2 | 19 | Alliance for Clinical Trials in OncologyOTHER | 2 | Mar 23, 2023 | clinicaltrials |
| NCT05338125 | Electrophysiology of the Human Pituitary Gland | terminated | N/A | 1 | Leiden University Medical CenterOTHER | 1 | Mar 13, 2023 | clinicaltrials |
| NCT02654340 | Biomarkers for Tuberous Sclerosis Complex (BioTuScCom)(TuScCom) | terminated | — | 20 | CENTOGENE GmbH RostockINDUSTRY | 8 | Feb 10, 2023 | clinicaltrials |
| NCT00659334 | Imaging of Intravenous (IV) Combidex to Brain, Intra-cerebral Tumors and in Central Nervous System (CNS) Inflammation | terminated | Phase 2 | 116 | OHSU Knight Cancer InstituteOTHER | 1 | Dec 21, 2022 | clinicaltrials |
| NCT03591861 | Therapeutic Targeting of Sex Differences in Pediatric Brain Tumor Glycolysis | terminated | N/A | 2 | Washington University School of MedicineOTHER | 1 | Dec 12, 2022 | clinicaltrials |
| NCT01954576 | NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma Multiforme | terminated | N/A | 21 | University of FloridaOTHER | 1 | Oct 31, 2022 | clinicaltrials |
| NCT02880111 | Rates DMBT1 ( Glycoprotein) in Sputum of CF Patients With Pseudomonas Aeruginosa(DMBT1) | terminated | — | 1 | University Hospital, LilleOTHER | 1 | Oct 18, 2022 | clinicaltrials |
| NCT02885324 | Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children | terminated | Phase 2 | 4 | Indiana UniversityOTHER | 1 | Oct 6, 2022 | clinicaltrials |
| NCT03352427 | Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations | terminated | Phase 2 | 3 | University of Michigan Rogel Cancer CenterOTHER | 1 | Oct 5, 2022 | clinicaltrials |
| NCT01884740 | Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22 | terminated | Phase 1 / Phase 2 | 13 | Weill Medical College of Cornell UniversityOTHER | 1 | Aug 9, 2022 | clinicaltrials |
| NCT03930771 | Capecitabine and Temozolomide for Treatment of Recurrent Pituitary Adenomas(TMZ-Cap) | terminated | Phase 2 | 1 | Weill Medical College of Cornell UniversityOTHER | 1 | Aug 9, 2022 | clinicaltrials |
| NCT02674945 | Understanding and Improving Quality of Life Through a Wireless Activity Tracker: Observational Phase | terminated | — | 29 | University of MinnesotaOTHER | 1 | Jun 28, 2022 | clinicaltrials |
| NCT00479765 | A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma | terminated | Phase 1 / Phase 2 | 4 | Boston Scientific CorporationINDUSTRY | 1 | Jun 22, 2022 | clinicaltrials |
| NCT03332589 | E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS) | terminated | Phase 1 | 4 | Spirita Oncology, LLCINDUSTRY | 1 | May 20, 2022 | clinicaltrials |
| NCT04460495 | Quantifying Oxygen Utilization of Tumors Using Oxygen-Enhanced Molecular MRI | terminated | N/A | 8 | Jonsson Comprehensive Cancer CenterOTHER | 1 | May 10, 2022 | clinicaltrials |
| NCT02419664 | Ga-68-DOTATOC -PET in the Management of Pituitary Tumours | terminated | Phase 3 | 22 | Göteborg UniversityOTHER | 1 | Mar 31, 2022 | clinicaltrials |
| NCT01925573 | Optune(NOVOTTF-100A)+ Bevacizumab+ Hypofractionated Stereotactic Irradiation Bevacizumab-Naive Recurrent Glioblastoma (GCC 1344) | terminated | N/A | 7 | University of Maryland, BaltimoreOTHER | 1 | Feb 3, 2022 | clinicaltrials |
| NCT05167370 | High Dose Chemotherapy With Amifostine and Autologous Stem Cell Transplantation for High Risk Relapsed Pediatric Solid Tumors and Brain Tumors | terminated | Phase 2 | 2 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Jan 25, 2022 | clinicaltrials |
| NCT02608307 | Medical Treatment Decision Making Using Adaptive Conjoint Analysis | terminated | — | 25 | St. Jude Children's Research HospitalOTHER | 1 | Dec 21, 2021 | clinicaltrials |
| NCT00972335 | Trial of the Combination of Bevacizumab and Everolimus in Patients With Refractory, Progressive Intracranial Meningioma | terminated | Phase 2 | 18 | SCRI Development Innovations, LLCOTHER | 1 | Nov 10, 2021 | clinicaltrials |
| NCT02212574 | Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma | terminated | Early Phase 1 | 6 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Nov 5, 2021 | clinicaltrials |
Data updated 23 days agoSource updated Oct 31, 2024source: clinicaltrials