Clinical trial · Interventional
Electrophysiology of the Human Pituitary Gland
Identification of the Posterior Lobe of the Human Pituitary Gland During Surgery Using Its Electrophysiological, Neural Signature
NCT05338125CI-TRIAL-00064644terminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): too busy for recruitment
Summary
Brief summary (as posted)
Measurment of electrophysiological properties of the human pituitary gland during removal of a pituitary adenoma. Assessment if these properties are sufficient for intra-operative identification of different tissues.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Diabetes Insipidus Cranial Type | — | UNRESOLVED | — |
| Endocrine; Deficiency | — | UNRESOLVED | — |
| Pituitary Adenoma | Pituitary Neuroendocrine Tumor | ALIAS | 0.90 |
| Pituitary Tumor | Pituitary Gland Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Micro-electrode measurement | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Intervention arm
- description
- Patients undergoing the extra intra-operative electrophysiological measurement
- interventionNames
- Procedure: Micro-electrode measurement
Primary outcomes (1)
- measure
- Electrophysiological properties
- timeFrame
- Day 0
- description
- Electrophysiological properties of the human pituitary gland
Secondary outcomes (2)
- measure
- Endocrine remission
- timeFrame
- 6 months postoperative
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Male and female patients undergoing transsphenoidal surgery for pituitary adenoma. * Identification of the posterior lobe on preoperative MRI. This is most common in patients with micro-adenomas or small macroadenomas. * Age \>18 years Exclusion Criteria: * Emergency surgery * Cognitive impairments * Pregnancy * Pre-existing diabetes insipidus
References
Publications (0)
Data not yet available
No reference posted for this study.